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Boston Red Sox vs New York Yankees Picks and Predictions April 22nd 2026
The Yankees and Red Sox are back at Fenway Park on Wednesday night, with first pitch set for 6:45 p.m. ET. New York comes in at 14-9, leading the AL East and riding a four-game winning streak, while Boston is 9-14, last in the division and five games back after dropping Tuesday’s opener. This is Game 2 of a three-game series, and it already feels important for Boston because the Red Sox are trying to keep this from turning into another stretch where the offense puts them in a hole early. Tuesday’s 4-0 Yankees win fit the broader trend. New York has won five of its last six, and Boston has now scored three runs or fewer in 12 of
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New York Mets vs Minnesota Twins Picks and Predictions April 22nd 2026
Minnesota heads to Citi Field on Wednesday night for the middle game of this series, with first pitch set for 7:10 p.m. ET on SNY. The Twins are 12-11 and second in the AL Central after Tuesday’s 5-3 comeback win, while the Mets have fallen to 7-16, fifth in the NL East, and are now carrying a 12-game losing streak into this matchup. That contrast is the whole handicap right now. One team has been uneven but competitive. The other keeps finding new ways to lose. The starter situation changed during the day. Minnesota is no longer listed with a TBD arm and will go with Connor Prielipp, while New York sticks with Clay Holmes. That matters because Holmes has
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Chicago Cubs vs Philadelphia Phillies Picks and Predictions April 22nd 2026
The Phillies head into Wrigley Field trying to stop a free fall. Philadelphia is 8-15, fourth in the NL East, just 2-8 over its last 10, and riding a seven-game losing streak. Chicago is moving the other direction at 14-9, second in the NL Central, 8-2 over its last 10, and on a seven-game winning streak. First pitch is set for 7:40 p.m. ET, with coverage listed on Marquee Sports Network and NBCSP+, and the weather around game time looks cool in the low 50s with light wind. That recent form matters here because the Cubs are not just squeaking by. They have a +37 run differential and have already taken the first two games of this series, winning 5-1
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Texas Rangers vs Pittsburgh Pirates Picks and Predictions April 22nd 2026
The Pirates and Rangers meet Wednesday night at Globe Life Field in Arlington, with first pitch set for 8:05 p.m. ET. Pittsburgh comes in at 13-10, fifth in the NL Central, while Texas is 12-11 and second in the AL West after opening the series with a 5-1 win on Tuesday. This is a pretty interesting early-season matchup because the records are close, the market is basically flat, and both teams have leaned on pitching more than explosive offense so far. Tuesday’s opener also gave this game a different feel. Texas held Pittsburgh to one run, got six solid innings from Kumar Rocker, and extended its home winning streak to four games, while the Pirates dropped to 5-5 on the
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Colorado Rockies vs San Diego Padres Picks and Predictions April 22nd 2026
The Padres and Rockies are back at Coors Field on Wednesday night, with first pitch set for 8:40 p.m. ET in Denver. San Diego comes in at 16-7 and second in the NL West, while Colorado is 9-15 and fifth after dropping Tuesday’s opener 1-0. The Padres have won three straight, and this is starting to feel like another spot where the better roster is trying to squeeze a divisional opponent before the market fully catches up. San Diego has been much steadier than Colorado in the early season sample, especially away from home. The Padres are 7-3 on the road, and even with an offense that has not fully clicked yet, they keep winning because the run prevention has

NHL Game Preview graphic featuring New Jersey Devils vs. Florida Panthers, with images of players from both teams.

New Jersey Devils vs Florida Panthers Picks and Predictions March 3rd 2026

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Desperation is the theme at the Prudential Center on Tuesday night as the Florida Panthers and New Jersey Devils meet in a … more

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Kansas State Wildcats vs West Virginia Mountaineers Picks and Predictions March 3rd 2026

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West Virginia Mountaineers vs Kansas State Wildcats Game Preview West Virginia heads to Bramlage Coliseum in Manhattan for a Big 12 road … more

NHL Game Preview: Blue Jackets vs Predators. Stay updated with the latest sports scores, picks, stats, odds, and analysis.

Columbus Blue Jackets vs Nashville Predators Picks and Predictions March 3rd 2026

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The Columbus Blue Jackets return home to Nationwide Arena on Tuesday night looking to build on a wild 5-4 overtime victory against … more

NHL game preview featuring the Capitals vs. Mammoth, with players in action on the ice.

Washington Capitals vs Utah Mammoth Picks and Predictions March 3rd 2026

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The Washington Capitals return to Capital One Arena on Tuesday night looking to protect a five-game home winning streak and wash away … more

NHL game preview with the Buffalo Sabres logo and the Vegas Golden Knights logo, featuring a player in a Sabres uniform and a goaltender in the background. Text reads "SABRES vs GOLDEN KNIGHTS" and "STAY UPDATED WITH THE LATEST SPORTS SCORES, PICKS, STATS, ODDS AND ANALYSIS!"

Buffalo Sabres vs Vegas Golden Knights Picks and Predictions March 3rd 2026

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The Buffalo Sabres finally return to KeyBank Center on Tuesday night after nearly a month away, and they couldn’t have asked for … more