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Universidad Católica travel to face Barcelona SC in Copa Libertadores Group D on Wednesday, April 29, 2026, at Estadio Monumental Banco Pichincha in Guayaquil. Kickoff is set for 8:00 PM ET, and this is a pressure-heavy group-stage spot for both clubs, just in different ways. Barcelona SC are bottom of the group with zero points through two matches. They lost 1-0 at home to Cruzeiro and then 3-0 away to Boca Juniors, so this is already close to a must-win spot if they want to stay alive in the group. Universidad Católica are in a better position after beating Cruzeiro away, but they also lost to Boca Juniors, so a road point here would still carry real value. The market

Independiente Santa Fe travel to face Platense in Copa Libertadores Group E on Wednesday, April 29, 2026, at Estadio Ciudad de Vicente López in Buenos Aires. Kickoff is set for 6:00 PM ET, and the group table makes this a pretty uncomfortable spot for the visitors. Platense are sitting second in Group E and can strengthen their qualification position with a home win. Santa Fe are fourth, which puts more pressure on them to take something from this trip. A loss would leave them chasing the group, and that changes how aggressive they may need to be as the match moves into the second half. The market has Platense favored, and that makes sense at home. Still, this is not

Always Ready travel to face Mirassol in Copa Libertadores Group G on Wednesday, April 29, 2026, at Estádio José Maria de Campos Maia in Mirassol, Brazil. Kickoff is set for 6:00 PM ET, and this is a big early group-stage spot for both teams, even if the market is not treating it as especially close. Mirassol enter as the strong favorite at home and sit ahead of Always Ready in the group. Always Ready are still trying to find traction in this section, and this is not an easy place to do it. They need points, but they also cannot afford to open the match too much against a home side that should have more control. That is the tension

Atlético Mineiro travel to face Deportivo Cienciano in Copa Sudamericana Group B on Wednesday, April 29, 2026, at Estadio Inca Garcilaso de la Vega in Cusco. Kickoff is listed for 8:30 PM ET, and this is one of the more interesting group-stage spots because Cienciano are currently top of the section, while Atlético Mineiro are close behind and trying to avoid falling into a tougher chase. Cienciano have four points through two group matches, with three goals scored and one allowed. Atlético Mineiro have three points, but their 3-3 goal profile says a lot about the current risk. They have enough quality to win this match, but they have also looked open enough to make the road price hard to