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Boston Red Sox vs New York Yankees Picks and Predictions April 22nd 2026
The Yankees and Red Sox are back at Fenway Park on Wednesday night, with first pitch set for 6:45 p.m. ET. New York comes in at 14-9, leading the AL East and riding a four-game winning streak, while Boston is 9-14, last in the division and five games back after dropping Tuesday’s opener. This is Game 2 of a three-game series, and it already feels important for Boston because the Red Sox are trying to keep this from turning into another stretch where the offense puts them in a hole early. Tuesday’s 4-0 Yankees win fit the broader trend. New York has won five of its last six, and Boston has now scored three runs or fewer in 12 of
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New York Mets vs Minnesota Twins Picks and Predictions April 22nd 2026
Minnesota heads to Citi Field on Wednesday night for the middle game of this series, with first pitch set for 7:10 p.m. ET on SNY. The Twins are 12-11 and second in the AL Central after Tuesday’s 5-3 comeback win, while the Mets have fallen to 7-16, fifth in the NL East, and are now carrying a 12-game losing streak into this matchup. That contrast is the whole handicap right now. One team has been uneven but competitive. The other keeps finding new ways to lose. The starter situation changed during the day. Minnesota is no longer listed with a TBD arm and will go with Connor Prielipp, while New York sticks with Clay Holmes. That matters because Holmes has
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Chicago Cubs vs Philadelphia Phillies Picks and Predictions April 22nd 2026
The Phillies head into Wrigley Field trying to stop a free fall. Philadelphia is 8-15, fourth in the NL East, just 2-8 over its last 10, and riding a seven-game losing streak. Chicago is moving the other direction at 14-9, second in the NL Central, 8-2 over its last 10, and on a seven-game winning streak. First pitch is set for 7:40 p.m. ET, with coverage listed on Marquee Sports Network and NBCSP+, and the weather around game time looks cool in the low 50s with light wind. That recent form matters here because the Cubs are not just squeaking by. They have a +37 run differential and have already taken the first two games of this series, winning 5-1
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Texas Rangers vs Pittsburgh Pirates Picks and Predictions April 22nd 2026
The Pirates and Rangers meet Wednesday night at Globe Life Field in Arlington, with first pitch set for 8:05 p.m. ET. Pittsburgh comes in at 13-10, fifth in the NL Central, while Texas is 12-11 and second in the AL West after opening the series with a 5-1 win on Tuesday. This is a pretty interesting early-season matchup because the records are close, the market is basically flat, and both teams have leaned on pitching more than explosive offense so far. Tuesday’s opener also gave this game a different feel. Texas held Pittsburgh to one run, got six solid innings from Kumar Rocker, and extended its home winning streak to four games, while the Pirates dropped to 5-5 on the
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Colorado Rockies vs San Diego Padres Picks and Predictions April 22nd 2026
The Padres and Rockies are back at Coors Field on Wednesday night, with first pitch set for 8:40 p.m. ET in Denver. San Diego comes in at 16-7 and second in the NL West, while Colorado is 9-15 and fifth after dropping Tuesday’s opener 1-0. The Padres have won three straight, and this is starting to feel like another spot where the better roster is trying to squeeze a divisional opponent before the market fully catches up. San Diego has been much steadier than Colorado in the early season sample, especially away from home. The Padres are 7-3 on the road, and even with an offense that has not fully clicked yet, they keep winning because the run prevention has

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Charlotte Hornets vs Sacramento Kings Picks and Predictions April 4th 2025

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Sacramento Nearing Must-Win Territory After three straight losses and defeats in seven of their past eight games, the Sacramento Kings (36-40) find … more

A hockey player in a blue jersey shoots the puck as the opposing goalie in red dives to block it, amidst an excited crowd.

Detroit Red Wings vs Carolina Hurricanes Picks and Predictions April 4th 2025

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Hurricanes Rolling In While Red Wings Face Must-Win Situation With just eight games left on the schedule, the Detroit Red Wings aren’t … more

Houston Players Celebration Huddle

Duke Blue Devils vs Houston Cougars Picks and Predictions April 5th 2025

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Building the Stage for a Historic Battle As Duke and Houston prepare to battle Saturday night in San Antonio, the story of … more

A coach engages with four Houston Rockets players, all in red uniforms, during a basketball game with fans in the background.

Houston Rockets vs Oklahoma City Thunder Picks and Predictions April 4th 2025

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Best of the West: Thunder Face Surging Rockets in Fifth Showdown With a dominant 143-105 victory over the Utah Jazz, the Houston … more

Two basketball players in dark uniforms celebrate on the court while another player in a light uniform looks on during a game.

La Clippers vs Dallas Mavericks Picks and Predictions April 4th 2025

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Anthony Davis Returns to LA as Mavericks Battle Clippers Friday night in Los Angeles brings a bit of drama — Anthony Davis … more