MLB Underdog Picks for Wednesday, June 22nd 2022

Major League Baseball returns for a full plate of midweek matchups, a majority of which have substantial consequences either in the division or postseason picture.

Top MLB Bookies

The New York teams have dominated thus far, while the Cleveland Guardians and San Diego Padres have made unexpected charges to their respective division titles.

Here are the top underdogs to consider on Wednesday.

Toronto Blue Jays vs. Chicago White Sox

Blue Jays vs. White Sox Prediction

Best Bet: White Sox ML (-101)

The White Sox went into game one of the ongoing series against the Blue Jays as sizable underdogs, but now that they have won two straight, each by one run, they have earned the respect of the oddsmakers as near-even favorites, though still slight underdogs.

Chicago has been able to overcome its suboptimal offense, which also lacks true sluggers, and has been without talisman Tim Anderson (now back to full health) and string together two highly impressive wins to remain alive and in contention for the American League Central.

Lucas Giolito (4-3, 4.78 ERA) will get the start after giving up eight earned runs in five innings against the Houston Astros in his last appearance.

The Blue Jays, meanwhile, have been one of the most disappointing teams in the league, not because of their record (38-30), but because this was the year that they were supposed to seriously contend for the World Series, and instead, they are 12 games behind the New York Yankees in the American League East and in a heated battle for second place.

Vladimir Guerrero Jr. has had an off-year, by his lofty standards, and the arrival of free-agent pitching talent has failed to make any sort of substantial impact.

Ross Stripling (3-2, 3.28 ERA) will get the start after giving up two earned runs in 3.2 innings against the Yankees his last time out.

MLB Odds

New York Mets vs. Houston Astros

Mets vs. Astros Prediction

Best Bet: Mets ML (+119)

Any time bettors can get the Mets for positive odds, it is seriously worth considering, whether that be on the moneyline or spread.

The Mets lost game one against the Astros 8-2 but have been so successful this season because of their ability to avoid long losing streaks, and now that they are under pressure from the resurgent Atlanta Braves, they will understand the importance of racking up wins before Max Scherzer and Jacob deGrom return from their respective injuries.

Carlos Carrasco (8-2, 3.96 ERA) will get the start after allowing three earned runs in6.1 innings against the Miami Marlins in his last bit of action.

The Astros are as solid of a team year-to-year as there is in the MLB, and they have won five of their last six games as they get ready to, in all likelihood, contend for another World Series.

Houston has a great balance between offense, defense, and pitching, which means that they will almost always be competitive in games, regardless of circumstance. Luis Garcia (4-5, 3.41 ERA) will get the start after giving up two earned runs in six innings against the Texas Rangers in his last start.

MLB Picks

St. Louis Cardinals vs. Milwaukee Brewers

Cardinals vs. Brewers Prediction

Best Bet: Cardinals ML (+101)

The Cardinals have been one of the most competitive teams in the National League Central division this season, and they have a great opportunity going against the Brewers— however, they could be without an injured Paul Goldschmidt, who is injured.

Nonetheless, they will have 40-year-old stud Adam Wainwright (5-5, 3.06 ERA) going for them, which should make their job much easier in the rubber match.

Milwaukee was expected to dominate the division but got a harsh reality check when they gave up the division lead, and they are now exactly tied with the Cards.

The Brew Crew relies on its pitching staff to carry it through games and does not have any menacing hitters, though they do get on base fairly consistently and tend to perform well in games that go down to the wire.

Eric Lauer (6-2, 3.57 ERA) will get the start after giving up four earned in 6.1 innings against the Cincinnati Reds.