Oakland Athletics vs Chicago White Sox Picks and Predictions April 25th 2025

A’s and White Sox Clash After Momentum-Building Wins

Both the Oakland Athletics and Chicago White Sox are riding high after key victories as they meet for a three-game weekend series beginning Friday night. With newfound confidence, each club will aim to build on their latest success and shift the tone of their seasons.

Athletics Riding High After Walk-Off Milestone

The Athletics are entering the series on a high note after Jacob Wilson’s clutch two-out, ninth-inning single lifted them to a 4-3 walk-off victory over the Texas Rangers on Thursday. It marked Oakland’s first series win at their temporary home in West Sacramento, Calif., and a much-needed boost for a team battling in a crowded American League West.

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“It’s just a cool moment being able to walk off a game and obviously help your team win,” Wilson said. “A great series win, and take this momentum going into tomorrow.”

“Tonight was a great night for our ballclub,” A’s manager Mark Kotsay added. “It just felt great, from a team standpoint, to get a win and a series win against a team that’s leading our division.”

Veteran Luis Severino will get the ball for Oakland in the opener. Severino (1-3, 3.31 ERA) finally secured his first win with the A’s last Saturday, tossing a vintage eight-inning gem against Milwaukee. Despite recording only one strikeout, Severino was effective by pounding the strike zone and inducing soft contact.

“Only one strikeout in eight innings, that’s old-school baseball,” Kotsay said. “He didn’t have a walk. He was pounding the zone, and they were putting the ball in play.”

Severino’s ability to mix his fastball and sweeper effectively could be key as Oakland seeks another strong start to the series.

White Sox Snap Historic Skid with Rain-Shortened Victory

The White Sox arrive with momentum of their own after snapping a 14-game losing streak at Target Field by defeating the Minnesota Twins 3-0 in a rain-shortened, seven-inning contest Thursday.

“Really cool to get the first win,” said White Sox rookie pitcher Shane Smith after notching his first major league victory. “Not the way you picture it, but… nothing is.”

Smith delivered a standout performance, striking out seven over five innings. Lenyn Sosa and Miguel Vargas provided the offense with home runs, helping Chicago secure just its second road win in 13 tries this season.

However, the White Sox will have to contend with their recent struggles against Oakland. The A’s swept them earlier this season in Chicago, dominating by a combined 23-4 scoreline in the series.

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If you’re eyeing this matchup for MLB picks, both teams come into this series with renewed energy. For the latest insights and expert analysis, be sure to explore the newest MLB picks to stay ahead of the action.

Pitching Matchup: Severino vs. Burke

Friday’s opener will feature a battle between right-handers Luis Severino and Sean Burke. While Severino brings a wealth of experience and a recent dominant outing, Burke (1-3, 6.23 ERA) is still finding his footing. In two career starts against Oakland, Burke has struggled with a 7.56 ERA.

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The Athletics hope Severino can continue to build on his old-school outing, while the White Sox will need Burke to find some consistency to keep pace with Oakland’s resurging offense.

Series Outlook

Both the A’s and White Sox are eager to capitalize on their momentum. With each team hungry for consistency and confidence, this series could offer the kind of emotional spark that shifts a season’s narrative.