San Francisco Giants vs Colorado Rockies Picks and Predictions May 4th 2025

Logan Webb, Giants Eye Series Win Against MLB-Worst Rockies

The San Francisco Giants are looking to secure another home series victory and keep the Colorado Rockies buried at the bottom of the standings. On Sunday afternoon, the Giants will turn to ace Logan Webb to help close out the four-game set with a third consecutive win at Oracle Park.

At 6-27, the Rockies are already 17 games behind the first-place Dodgers in the NL West — and it’s only early May. As Colorado continues to search for traction, San Francisco is capitalizing on winnable matchups.

Check out the latest game odds and lines at the MLB Odds Page.

Giants Riding Webb, Timely Hitting into Finale

Logan Webb (3-2, 2.83 ERA) is set to make his eighth start of the season, and despite a rocky outing last time out in San Diego (5 ER in 5 IP), he’s been reliable overall — including strong performances at home.

Webb’s success against the Rockies has been well-documented. He owns an 8-3 record with a 3.23 ERA in 16 career appearances (15 starts) vs. Colorado — his most wins against any opponent.

For deeper pitcher-vs-team analytics, visit the MLB Expert Betting Guide.

Rockies Counter with Struggling Marquez

Opposing Webb is German Marquez (0-5, 9.82 ERA), who’s had a disastrous start to 2025. The veteran righty has allowed 6+ earned runs in four straight starts, and his most recent outing against the Braves saw him give up seven runs and 11 hits in just 5 1/3 innings.

Yet, Marquez remains optimistic.

“I changed my delivery a little bit and felt good,” Marquez said after his last start. “Every outing is a chance to turn things around.”

That’s going to be a tough ask in San Francisco. Marquez has struggled at Oracle Park, and his overall numbers against the Giants are rough: 5-10 with a 6.62 ERA in 17 career starts.

Track pitching breakdowns and ERA splits at the MLB Picks Hub.

Chapman Leads Timely Giants Offense

While the Giants haven’t been mashing the ball — just 12 hits over their last two games — they’ve been clutch when it counts.

Matt Chapman has emerged as the offensive spark plug, launching a solo homer Friday and delivering a grand slam Saturday that turned the tide in a 6-3 win.

“It’s not how many hits, it’s when they come,” manager Bob Melvin said. “Chapman’s been huge for us.”

Chapman is hitting just .205, but his 7 home runs and 21 RBIs have come at the right moments.

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Rockies Offense Fading Fast

Colorado’s bats have gone cold. In their two losses this series, the Rockies failed to produce a single extra-base hit and have just 16 hits over the first three games. Their seven runs this series? Four came in Thursday’s opener.

It’s no surprise that they rank at the bottom of the NL in batting average, OBP, and slugging percentage.

Get the full breakdown of struggling teams and top fade candidates on the MLB Leaderboard.

Key Stats and Series Snapshot

The Giants have won three of four series at home this year and are looking to add another to that resume. Meanwhile, the Rockies are reeling and hoping not to be swept out of yet another weekend set

Final Word

This game features two pitchers on very different trajectories. Webb has historically owned the Rockies, and with their offense slumping, he’ll look to bounce back from a rare subpar outing. Marquez, meanwhile, is trying to prevent his season from spiraling further.

San Francisco should have the edge in this one, but if Colorado can find a way to get to Webb early, they may be able to avoid another lost series.

Prediction: Giants 5, Rockies 2