Los Angeles Dodgers vs Arizona Diamondbacks Picks and Predictions May 21st 2025

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As the Los Angeles Dodgers fight to regain momentum following a rare four-game skid, all eyes turn to Dustin May, who faces a crucial test against the Arizona Diamondbacks. With a depleted starting rotation and limited options, the Dodgers are making a bold move: sending May to the mound on just four days’ rest — a first since his return from Tommy John surgery in 2023.


Dodgers Snap Losing Streak, Eye Series Win

After four consecutive losses, the Dodgers eked out a much-needed 4-3 victory in a ten-inning thriller Tuesday night. Thanks to seven dominant, scoreless innings by ace Yoshinobu Yamamoto, Los Angeles finally halted its losing skid. The offense came alive just in time, notching three runs in the 10th inning to clinch the win.

But the game wasn’t without drama. Arizona catcher Gabriel Moreno hit a game-tying homer in the 9th — his third home run of the season, all against the Dodgers — and Corbin Carroll launched a two-run shot in the 10th to temporarily put Arizona ahead.


Injuries Force Dodgers to Accelerate May’s Schedule

The win did little to solve Los Angeles’ larger issue: a battered rotation. With Roki Sasaki and two other starters sidelined, manager Dave Roberts is navigating rough waters.

Enter Dustin May, who last pitched just four days ago. Roberts addressed the decision candidly:

“I think it’s more the need of the rotation. I think he’s physically able to handle it… The progression is kind of fitting and the timing is good for this.”

May’s numbers haven’t inspired confidence lately. He’s 1-4 with a 4.43 ERA and is on a three-game losing streak. In his last start, he surrendered four runs over five innings in a loss to the Angels.

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May vs. Diamondbacks: A Familiar Matchup

This isn’t May’s first rodeo against Arizona. In six career appearances (five starts), he’s 1-2 with a 3.96 ERA. Just eleven days ago, he squared off with the D-backs and allowed two runs across 5 1/3 innings in a 3-0 loss.

Tonight’s rematch features the same foe on the mound: Corbin Burnes, who blanked the Dodgers for seven innings on May 10 and is on a 16-inning scoreless streak.

Burnes, who boasts a 3-1 record and 2.56 ERA, has quietly dominated in recent starts, most recently shutting down the Rockies over six scoreless frames. Against the Dodgers, he’s 3-3 with a 4.38 ERA in nine career outings. Check The latest Baseball Picks from MLB Expert Handicappers


Tuesday’s Thriller: A Microcosm of the Season

Tuesday night highlighted the unpredictable nature of the Dodgers’ season. They were no-hit through six innings, then surged back late with crucial hits and a walk-off sacrifice fly by Max Muncy.

Despite the loss, Arizona manager Torey Lovullo praised his team’s resilience:

“Our guys were fighting the whole day… It would have been kind of a steal win for us… but it wasn’t in the cards.”


What’s at Stake for Dustin May and the Dodgers?

This outing is pivotal for both May and the Dodgers:

  • For May, it’s a chance to snap his losing streak and prove he can handle high-leverage situations post-surgery.
  • For the Dodgers, it’s about keeping pace in a competitive division while juggling an injury-riddled rotation.

If May can deliver a solid performance on short rest, it may signal a turning point for both his comeback journey and the Dodgers’ pitching depth crisis.

By Taylor Smith | April 8, 2025
By Taylor Smith | April 1, 2025
By Taylor Smith | March 29, 2025
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Mike Williams
Mike Williams | Handicapper

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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