D-backs vs Reds: Arizona Rolls into Cincinnati Hot

Cincinnati Reds vs Arizona Diamondbacks June 6th 2025

The Arizona Diamondbacks will visit the Cincinnati Reds at Great American Ball Park on Friday, June 6, 2025. The game is set to start at 7:10 PM under the lights. Fans can catch the action on APLTV, with weather conditions expected to be warm with a light breeze and broken clouds.

The Diamondbacks, managed by Torey Lovullo, come into the game with a 31-31 record. They have been solid on the road with a 16-14 record. The Reds, led by Terry Francona, hold a 30-33 record. At home, they have a record of 15-16. Eduardo Rodriguez will start for the Diamondbacks, while Nick Lodolo takes the mound for the Reds.

Diamondbacks vs Reds Key Information

Sport: Baseball
Teams: Arizona Diamondbacks vs. Cincinnati Reds
Venue: Great American Ball Park in Cincinnati, OH
Date: Friday, June 6, 2025
Betting Odds: Diamondbacks MoneyLine -110, Reds MoneyLine -109

The Diamondbacks Can Win If…

The Arizona Diamondbacks are coming off a high-scoring win against the Atlanta Braves, 11-10. Key players like Ketel Marte and Alek Thomas each hit a home run, contributing to the team’s 12 hits and 6 extra-base hits. Their offense is on a roll, with consistent performances over the past few games.

Arizona’s batting lineup is strong, ranking 3rd in slugging percentage at .448 and 4th in home runs with 87. The team also leads the league in doubles with 121. This potent offense can be a challenge for any opponent, making them a threat in every game.

Ketel Marte stands out with a .299 batting average and 11 home runs. Eugenio Suárez adds power with 16 home runs, leading the team. With these hitters in form, Arizona has the potential to outscore their opponents, even against strong pitching.

The Reds Can Win If…

The Cincinnati Reds are looking to bounce back after their recent 1-9 loss to the Milwaukee Brewers. Despite the defeat, Jose Trevino was a standout performer, going 3 for 4 with two doubles. The Reds have shown they can win, as seen in their 4-2 victory over the Brewers on June 3rd, where Tyler Stephenson and Will Benson each hit a home run.

The Reds’ offense is capable, ranking 7th in doubles and 4th in stolen bases this season. Elly De La Cruz is a key player with 12 home runs and 43 RBIs, leading the team in both categories. With a solid on-base percentage of .318, the Reds can put pressure on opposing pitchers and create scoring opportunities.

Nick Lodolo takes the mound for the Reds, bringing a 3.10 ERA and 1.10 WHIP to the game. His consistency gives the Reds a strong chance against the Diamondbacks’ starter, Eduardo Rodriguez, who has a 7.05 ERA. Lodolo’s ability to limit hits and keep runners off base will be crucial for the Reds to secure a win.

The Lean

The Diamondbacks are slight favorites with a MoneyLine of -110. The Reds have a MoneyLine of -109. Given the Diamondbacks’ stronger batting stats, including a higher slugging percentage and more home runs, the pick is for the Diamondbacks to win. The model projects a score of Diamondbacks 5, Reds 4.

The over/under is set at 9.0. With both teams having decent hitting and the Diamondbacks’ pitching having a high ERA, the game may see more runs. The model projects a total of 9 runs, so the recommendation is to take the over.

After Historic Comeback, D-backs Open Series vs. Slumping Reds

The Arizona Diamondbacks arrive in Cincinnati on a roll after a jaw-dropping 11-10 comeback win over Atlanta. Arizona scored seven runs in the ninth inning Thursday to complete a sweep of the Braves, marking their largest ninth-inning comeback in team history.

The D-backs have now won four straight — their best stretch since April — and will look to keep it going with the return of Eduardo Rodriguez (1-3, 7.05 ERA), activated from the IL. He last pitched on May 14 before missing time with shoulder inflammation.

Arizona swept Cincinnati last season and looks confident entering this three-game series.

Reds Reeling, Injuries Mounting

The Cincinnati Reds have lost four of their last five and just dropped a series to Milwaukee. They’re now 5-9 in their past 14 games, falling to fourth in the NL Central.

Hunter Greene is back on the IL with a recurring groin issue, adding more pressure to a rotation already leaning on Nick Lodolo (4-4, 3.10 ERA), who starts Friday. Lodolo pitched six scoreless innings in his last outing vs. the Cubs but received no run support.

Cincinnati’s pitching staff ranks 12th in team ERA (3.80), but the offense has struggled to string wins together.

A baseball pitcher in a bright red Cincinnati Reds jersey winds up to throw a baseball during a game, showcasing athleticism and focus.

Key Injuries and Rotations

Rodriguez makes his return from injury with hopes of recapturing form. In two career starts vs the Reds, he has a 2.77 ERA. Lodolo, meanwhile, has never faced Arizona but has been sharp in recent outings.

Designated hitter Josh Naylor is day-to-day for Arizona with shoulder and hand soreness. His status for the opener remains uncertain.

Stay sharp on this series and more with real-time MLB odds, expert picks, and full team analysis in the MLB expert guide and MLB team hub.

FAQs

Who is starting for the Diamondbacks Friday?

Eduardo Rodriguez will make his return from the IL.

Who pitches for the Reds in Game 1?

Nick Lodolo (4-4, 3.10 ERA) gets the start for Cincinnati.

What’s Arizona’s current win streak?

The Diamondbacks have won four straight games.

Is Josh Naylor playing Friday?

He is day-to-day due to shoulder and hand soreness.

How did the teams perform against each other last season?

Arizona went 5-1 vs Cincinnati, including a sweep in Ohio.

Cincinnati Reds vs Arizona Diamondbacks Picks and Predictions June 6th 2025