San Francisco Giants vs Cleveland Guardians June 17th 2025

The Cleveland Guardians are set to take on the San Francisco Giants at Oracle Park. This night game on June 17, 2025, starts at 9:45 PM. Fans can catch the action on CLEG under clear skies and mild weather conditions.

Stephen Vogt’s Guardians have a balanced record of 35-35 this season. They will face Bob Melvin’s Giants, who hold a 41-31 record. On the mound, Slade Cecconi will pitch for the Guardians, while Robbie Ray starts for the Giants.

Guardians vs Giants Key Information

• Sport: Baseball
• Teams: Cleveland Guardians vs. San Francisco Giants
• Venue: Oracle Park in San Francisco, CA
• Date: Tuesday, June 17, 2025
• Betting Odds: Guardians MoneyLine +136, Giants MoneyLine -162

The Guardians Can Win If…

The Cleveland Guardians are looking to bounce back after a tough series against the Seattle Mariners. In their most recent game, they fell 0-6, but they have shown flashes of strong performances in recent games. José Ramírez continues to be a key player, hitting .324 with 13 home runs and 34 RBIs this season.

The Guardians have some strengths that could help them win the next game. They rank 10th in stolen bases with 56, and their pitchers have only blown six saves, which is the best in the league. Their pitching staff also has a respectable 3.99 ERA, which ranks 19th.

Slade Cecconi will start for the Guardians, and he has a 4.26 ERA and 1.34 WHIP. The team will rely on his ability to keep the game close against the Giants. With players like Steven Kwan and Carlos Santana in the lineup, the Guardians have the potential to put runs on the board.

The Giants Can Win If…

The San Francisco Giants are set to play the Cleveland Guardians, and they have strong reasons to believe in a win. In their recent game against the Dodgers, the Giants lost 4-5, but they showed offensive power with 7 hits and a home run by Daniel Johnson. Sean Hjelle pitched 3 2/3 innings, striking out 5 batters, showing potential for future games.

The Giants have solid team stats that can lead them to victory. They hold a 3.30 ERA, which ranks 3rd in the league, and their pitching staff has given up only 55 home runs, ranking 2nd. With Robbie Ray on the mound, boasting an impressive 2.54 ERA and an 8-1 record, the Giants have a reliable ace to lead them.

Offensively, the Giants have key players who can make a difference. Rafael Devers, with a .272 batting average and 15 home runs, is a threat in the lineup. Heliot Ramos, hitting .286, adds depth, while Dominic Smith’s .343 average provides consistency at the plate. These players, along with a strong pitching performance, give the Giants a good chance to secure a win against the Guardians.

The Lean

The Giants are favored with a moneyline of -162, while the Guardians are at +136. My model projects the Giants to win 4-3. The Giants have a strong pitching edge, ranking 3rd in ERA and 8th in batting average against, which supports picking them to win straight up.

The total for the game is set at 7.0. My model projects a total score of 7, which matches the line. With both teams having solid pitching, especially the Giants’ low ERA, the under 7.0 is a reasonable pick.

Score a Homerun!

With our Premium Handicapping Membership

Get Free Trial

Devers Set for San Francisco Debut as Giants Host Slumping Guardians

The San Francisco Giants could be welcoming a new face of the franchise Tuesday night as they open a three-game interleague series against the Cleveland Guardians. Three-time All-Star Rafael Devers, acquired Sunday in a blockbuster trade with Boston, is expected to make his home debut at Oracle Park.

While Devers’ arrival energizes the lineup, questions remain about where he will take the field. The Giants are currently dealing with injuries and shuffling pieces across the infield, and the addition of Devers only adds to that strategic puzzle.

Giants Weigh Defensive Options as Offense Gets a Boost

The Giants have been thin at first base since trading LaMonte Wade Jr. earlier this month. Dominic Smith has filled the void, starting 10 of the last 11 games. Meanwhile, Matt Chapman — the team’s defensive anchor at third base — is sidelined with a sprained hand. Casey Schmitt has stepped up recently, starting six straight games and delivering grand slams in back-to-back contests against the Dodgers.

With this evolving infield situation, Giants leadership — including manager Bob Melvin and president of baseball operations Buster Posey — will meet with Devers to evaluate how he fits into the on-field configuration.

Still, San Francisco ace Logan Webb sees only upside.

“He’s a guy you plug in there every day,” Webb said. “I don’t know where he’s going to hit, but I don’t think it really matters. The guy is a stud, plain and simple.”

For more expert evaluations and player trends, check out the full MLB picks and predictions section.

Offensive Momentum Arrives at the Right Time

San Francisco is showing signs of life offensively after a lengthy dry spell. The team scored four or more runs in each of its six road games through Colorado and Los Angeles, a stark contrast to the prior stretch when they failed to reach that number in 19 of 21 games. However, power at Oracle Park remains limited — the Giants hit just four home runs over their most recent six-game homestand.

That could change with Devers, who hit his 15th home run of the season in his Red Sox finale on Sunday. He brings immediate pop to a team that has struggled to generate consistent long-ball threats.

To dive deeper into matchup data and betting angles, explore our MLB game previews.

Tuesday’s Matchup: Ray vs. Cecconi

Veteran left-hander Robbie Ray (8-1, 2.55 ERA) gets the start for San Francisco. He’s been dominant against Cleveland in his career, compiling a 2-1 record with a 1.93 ERA over five starts. Ray will face Guardians slugger Jose Ramirez, who recently saw his 39-game on-base streak end in Sunday’s 6-0 loss to Seattle.

Ramirez has struggled against Ray, going hitless in his last 10 plate appearances versus the lefty after recording a single in their first matchup in 2021.

Cleveland counters with right-hander Slade Cecconi (1-3, 4.26 ERA), who will face Devers for the first time. Devers has a .335 career average against the Guardians and went 5-for-13 in their three-game April series, including two homers and a double.

The Guardians are reeling after being swept in Seattle, scoring just five runs over the three-game set. Offensively, they need Ramirez and the heart of the lineup to deliver to stop the skid.

Giants’ Lineup Shaping Into Contender Form

While Devers’ debut draws the headlines, San Francisco’s recent surge is a product of strong bullpen work and timely hitting. The team has climbed back to .500 and appears poised to challenge in the NL West with reinforcements arriving.

For bettors looking for premium selections and data-driven insights, check out our expert MLB betting guide and curated buy picks section.

What’s at Stake

This series serves as a temperature check for both clubs. The Guardians aim to reset after a tough series, while the Giants look to maintain momentum with their newest slugger in the fold. If Devers can anchor the offense and Ray continues his form, San Francisco could be positioned for a strong second-half push.

Track top performing MLB experts and their records at our handicappers leaderboard to stay ahead of the betting curve.