Colorado Rockies vs Arizona Diamondbacks Picks and Predictions June 21st 2025

Colorado Rockies vs Arizona Diamondbacks MLB Sat, Jun 21, 20:10 pm.
Colorado Rockies
ML: 165
0
0
Arizona Diamondbacks
ML: -213
Last Updated on

The Arizona Diamondbacks enter the middle game of their three-game set in Denver having split their first four head-to-head matchups this season against the Rockies. After dropping the opening two contests of a nine-game road trip, Arizona has rebounded with consecutive wins, including a 14-8 victory on Friday night in which Eugenio Suarez launched his 300th career home run and the club tallied a season-high 21 hits. For deeper game-by-game breakdowns, see our MLB series previews.

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Pitching Matchup Breakdown

On the mound for Arizona is right-hander Merrill Kelly (6–3, 3.41 ERA), who has been dominant in June, allowing just two earned runs over his first 13 innings of the month. Kelly owns an 8–3 record with a 3.26 ERA in 16 career starts against Colorado and will aim for a third straight victory in this series. Opposing him is Rockies lefty Carson Palmquist (0–4, 7.76 ERA), still hunting his first big-league win. When analyzing pitching trends and wagering angles, consult our latest MLB picks.

Injury Report and Lineup Updates

Arizona’s depth has been tested by injuries. Catcher Gabriel Moreno was placed on the 10-day injured list retroactive to Monday with a hairline fracture in his right hand and is expected to miss time through the All-Star break. Outfielder Corbin Carroll, sidelined for the last two games with a left-hand contusion, is trending positively and could rejoin the lineup Saturday night if all goes well. Unfortunately, pitchers A.J. Puk, Christian Montes De Oca and Justin Martinez appear headed for season-ending stints on the injured list. To understand how injuries shift betting markets, check out our expert MLB betting guide.

Betting Outlook and Premium Picks

This matchup offers several wagering angles based on run lines, total runs and prop markets. For readers seeking top-tier selections, visit our Buy Picks page to access premium insights and projections tailored to this game.

Division Standings and Outlook

The Diamondbacks sit eight games back of the NL West–leading Dodgers, making each divisional contest critical. Colorado, meanwhile, has rallied to an 8–9 mark over its last 17 games after a discouraging 9–50 start. Both clubs will look to leverage home-field advantage and key pitching matchups as they jockey for position. Keep an eye on the Best Handicappers Leaderboard to see which analysts are excelling this season.

By Kody Miller | July 18, 2025
By Kody Miller | July 18, 2025
By T. Franklin Smith | July 17, 2025
spread
moneyline
over/under
Colorado Rockies
-
-
165
O 12.5
100
Arizona Diamondbacks
-
-
-213
U 12.5
-125
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Mike Williams | Handicapper

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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