Houston Astros vs Boston Red Sox Picks and Predictions August 12th 2025

Houston Astros vs Boston Red Sox August 12th 2025

The Boston Red Sox will play against the Houston Astros at Daikin Park in Houston, TX. The game is set for Tuesday, August 12, 2025, at 8:10 PM. Fans can catch the action on SCHN.

Boston enters the game with a 65-55 record, holding the second spot in the AL East. They have lost their last three games. The Astros, leading the AL West with a 67-52 record, have won their last two games. The starting pitchers are Dustin May for Boston and Spencer Arrighetti for Houston.

Red Sox vs Astros Key Information

• Sport: Baseball
• Teams: Boston Red Sox vs. Houston Astros
• Venue: Daikin Park in Houston, TX
• Date: Tuesday, August 12, 2025
• Betting Odds: Red Sox Moneyline +100, Astros Moneyline -118

The Red Sox Can Win If…

The Boston Red Sox recently played against the Houston Astros and lost 7-6. Despite the loss, the Red Sox showed strong hitting with 10 hits and 3 home runs. Roman Anthony and Alex Bregman both had home runs, contributing to the team’s offensive efforts.

The Red Sox have a solid batting lineup, ranking 5th in slugging percentage at .429. They also lead the league in doubles with 247. This ability to hit for power and extra bases gives them a chance to score runs quickly.

On the mound, Dustin May is set to start for the Red Sox. He will face Spencer Arrighetti, who has an ERA of 7.42. This matchup gives Boston a good opportunity to capitalize on pitching struggles and secure a win.

The Astros Can Win If…

The Houston Astros are coming off a close 7-6 win against the Boston Red Sox. In that game, Ramón Urías had a standout performance with a home run and two RBIs. Cristian Javier pitched five innings, allowing only two earned runs, helping secure the victory.

Houston’s hitting stats show they are a strong offensive team. They have the second-best batting average in the league at .259. Their ability to get on base and score runs makes them a tough team to beat.

The Astros’ pitching is also a key factor in their success. They rank third in batting average against, holding opponents to a .230 average. With a strong bullpen and solid starters, they can control the game from the mound.

The Lean

The Astros are favored with a moneyline of -118 against the Red Sox at +100. The Astros have a strong pitching staff with a 3.71 ERA, ranked 7th, and their batting average against is .230, ranked 3rd. My model projects the Astros to win with a score of 5-3, making them the pick for the moneyline.

The total for the game is set at 8.5 runs. The Red Sox have a solid slugging percentage of .429, ranked 5th, and the Astros have given up 139 home runs, ranked 16th. My model projects a total of 8 runs, so the recommendation is to take the under at 8.5.

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Astros Seek More Impact From Deadline Additions in Rematch vs. Red Sox

The Houston Astros wasted no time showing their home crowd what their trade-deadline reinforcements could bring to the lineup. In Monday’s 7-6 victory over the Boston Red Sox, Carlos Correa delivered a key RBI single, Ramon Urias blasted a two-run homer, and Jesus Sanchez made an appearance as a pinch hitter late in the game. The offensive boost was a welcome sight for a club that has battled injuries to key hitters all season.

Still without Yordan Alvarez (hand) and Jake Meyers (calf), Houston found a way to break through against Boston ace Garrett Crochet. The Astros scored in bunches early, flashing what their lineup might look like at full strength. “Yes, and imagine when those guys get back,” Astros manager Joe Espada said. “But they’re not here right now, and I give credit to the guys who continue to battle every day. They’re giving quality at-bats, and we’re fighting through this.”

Bullpen Tested by Injuries

Houston’s injury concerns extended beyond the lineup in the opener. All-Star closer Josh Hader had his left shoulder examined pregame due to discomfort, and key setup relievers Bryan King and Bryan Abreu were also unavailable. That forced Espada to mix and match over the final four innings to hold off Boston’s rally. “That was kind of fun,” Espada said. “I trust this bullpen. These guys have been good for us all year, and we need them.”

Arrighetti Returns to Rotation

Right-hander Spencer Arrighetti (1-2, 7.43 ERA) will make his second start since returning from a four-month stint on the injured list with a fractured thumb. His comeback outing last Wednesday against the Miami Marlins was rocky — five runs allowed on 11 hits in 3 2/3 innings — but the Astros still value the upside he flashed as a rookie. One of his best career starts came against Boston last Aug. 10, when he struck out 13 over seven innings in a 5-4 win.

Red Sox Counter With May

Boston turns to right-hander Dustin May (6-8, 4.93 ERA), who will make just his second start since being acquired from the Los Angeles Dodgers at the trade deadline. May struggled in his debut for Boston, allowing three runs on six hits over 3 2/3 innings in a loss to the Kansas City Royals. Over his last seven starts overall, he is 3-3 with a 5.54 ERA. His lone career start against the Astros came back in 2020, when he allowed one run over 3 1/3 innings.

Probable Starters – 2025 Season

Notable Returns and Reunions

Monday also marked Carlos Correa’s first home game in Houston since being reacquired from the Minnesota Twins. The two-time All-Star, who helped the Astros win the 2017 World Series, received a warm reception before delivering an RBI that helped spark Houston’s early scoring burst.

On the other side, Alex Bregman — now playing third base for Boston after nine seasons in Houston — made a strong return to Minute Maid Park, going 2-for-4 with a home run. “I feel like we’re playing really good baseball,” Bregman said. “Everyone is getting better every single game, and I think we’ll be right where we want to be.”

The scores and odds page offers the latest betting lines for Tuesday’s rematch, while the expert betting guide provides a deeper dive into both starters’ recent form.