Cincinnati Reds vs Milwaukee Brewers Picks and Predictions August 16th 2025

Cincinnati Reds vs Milwaukee Brewers August 16th 2025

The Milwaukee Brewers travel to Great American Ball Park to take on the Cincinnati Reds. The Brewers hold a strong record of 77-44 and sit at the top of the NL Central. They are on a 13-game winning streak and have won their last 10 games. Pat Murphy leads the team, with Quinn Priester as the starting pitcher for this game. Priester has an ERA of 3.49 and a record of 11-2.

The Cincinnati Reds, managed by Terry Francona, have a record of 64-59 and are third in the NL Central. They have a home record of 35-28 but are coming off a loss. Zack Littell will start for the Reds, with an ERA of 3.60 and a 9-8 record. The game is set for Saturday, August 16, 2025, at 6:40 PM, with weather conditions expected to be very hot and scattered clouds. Fans can watch the game on FDSWI.

Brewers vs Reds Key Information

• Sport: Baseball
• Teams: Milwaukee Brewers vs. Cincinnati Reds
• Venue: Great American Ball Park in Cincinnati, OH
• Date: Saturday, August 16, 2025 at 6:40 PM
• Betting Odds: Brewers Moneyline -132, Reds Moneyline +113, Brewers Runline -1.5 (+119), Reds Runline +1.5 (-143), Total Over 9.0 (-121), Total Under 9.0 (+100)

The Brewers Can Win If…

The Milwaukee Brewers are on a strong winning streak, coming off a 10-8 victory against the Cincinnati Reds. Christian Yelich was a standout player, going 4 for 5 with two home runs and five RBIs. Andrew Vaughn also contributed with a home run and three RBIs, showing the depth of the Brewers’ lineup.

Milwaukee’s hitting stats are impressive, with a team batting average of .260, ranked second in the league. Their on-base percentage is also second at .332, indicating their ability to get on base and create scoring opportunities. This offensive power is backed by players like Yelich, who has 25 home runs this season.

The Brewers’ pitching staff is also a key factor in their success, with an ERA of 3.63, which ranks third in the league. Quinn Priester, the starting pitcher for the next game, has a solid record of 11-2 with a 3.49 ERA. With strong hitting and pitching, the Brewers have a solid chance to continue their winning ways.

The Reds Can Win If…

The Cincinnati Reds are looking to bounce back after a 10-8 loss to the Milwaukee Brewers. Despite the loss, the Reds had strong performances from Elly De La Cruz and Gavin Lux. De La Cruz drove in two runs, while Lux had two hits and two RBIs, showing the depth in the lineup.

The Reds have a solid chance to win with their batting stats. They rank 10th in batting average and doubles this season. This consistent hitting can help them put runs on the board against any opponent.

Starting pitcher Zack Littell will take the mound for the Reds. Littell has a 3.60 ERA and a WHIP of 1.12, which shows he can keep the game close. With the Reds’ ability to hit and Littell’s pitching, they have a good shot at securing a win.

The Lean

The Brewers are favored with a moneyline of -132 against the Reds at +113. The Brewers have a strong pitching staff with a 3.63 ERA, ranked 3rd, which gives them an edge. My model projects the Brewers to win with a score of 5-4, making them the pick for this game.

The total for the game is set at 9.0 runs. The Brewers’ pitching strength and the Reds’ average hitting suggest a lower-scoring game. My model projects a total of 9 runs, so the recommendation is to take the under at 9.0 (+100).

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Brewers Aim for 14 Straight in Cincinnati

Fresh off a stunning comeback that erased an 8–1 hole in a 10–8 win, the Brewers head back to Great American Ball Park on Saturday with a chance to set a new franchise mark: 14 consecutive victories. The surge has Milwaukee 33 games over .500 and firmly in control of the league’s best record. For a broader snapshot of the matchup before first pitch, visit the MLB previews hub.

Friday’s Epic Rally Sets the Stage

Friday’s opener had everything. Christian Yelich delivered a four-hit, two-homer, five-RBI performance and came up a triple shy of another cycle. Milwaukee’s lineup kept grinding after the early deficit, flipping momentum and silencing the crowd. Cincinnati now has to regroup quickly after letting a seven-run lead vanish. Track how results are trending day to day across the league with the latest MLB game results.

Probable Pitching Matchup

Milwaukee turns to right-hander Quinn Priester (11–2, 3.49 ERA), who has been steady and effective deep into the summer. He’s shown poise against Cincinnati before and profiles to attack with a balanced mix that plays well early in counts.

Cincinnati counters with right-hander Zack Littell (9–8, 3.60), recently acquired at the deadline. Littell fills the zone, leans on weak contact, and typically works efficiently through the first two trips in the order. How he navigates Milwaukee’s left-handed bats the third time through could decide the night. For additional game-day context and angles, scan today’s board of MLB picks.

Series Trends and Context

The Brewers have dominated this matchup in recent years, including a strong record this season. Milwaukee’s approach has traveled: disciplined at-bats, opportunistic base running, and timely extra-base hits. Cincinnati must convert routine plays and strand traffic to avoid another momentum swing. If you’re building your own angles, the longform strategy hub, the MLB expert betting guide, is useful for weighing recent form, bullpen usage, and park effects.

Betting Outlook and How to Play It

Milwaukee’s combination of contact quality, late-inning resilience, and a settled leverage crew gives the Brewers a tangible edge if the game is close after five. Cincinnati’s path centers on striking early against Priester and protecting the middle innings, where the last game turned. Compare viewpoints and see where the market and experts align on today’s card, then consider upgrading with premium picks and checking who’s running hot on the best handicappers leaderboard.

Players’ Weekend Note

This series coincides with Players’ Weekend, and Christian Yelich honored Brewers legend Bob Uecker with a baby blue bat featuring Uecker’s likeness. It’s a small detail, but it captures the mood around the clubhouse: loose, motivated, and fully locked in.

Bottom Line

Milwaukee’s plate discipline and bullpen sequencing have been the difference during the streak, and Friday’s comeback only reinforced the Brewers’ ability to win in multiple ways. Cincinnati needs clean defense and early offense to flip the script, but if this one tightens late, Milwaukee’s recent blueprint again looks favorable. For a final pregame check on injuries, lineups, and any late steam, circle back to the MLB previews feed and the latest MLB picks.