Kansas City Royals vs Chicago White Sox Picks and Predictions August 16th 2025

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The Chicago White Sox will visit the Kansas City Royals at Kauffman Stadium on Saturday, August 16, 2025. The game is set to start at 7:10 PM and will be broadcast on CHSN. The weather forecast predicts a very hot day with a light breeze and few clouds.

The White Sox are currently in a rough patch with a record of 44-78 and a two-game losing streak. They are fifth in the AL Central. On the other hand, the Royals have a balanced record of 61-61 and are third in the same division. Kansas City recently snapped a losing streak with a win, and they have been 5-5 in their last ten games.

White Sox vs Royals Key Information

  • Sport: Baseball
  • Teams: Chicago White Sox vs. Kansas City Royals
  • Venue: Kauffman Stadium in Kansas City, MO
  • Date: Saturday, August 16, 2025
  • Betting Odds: White Sox Moneyline +140, Royals Moneyline -166, White Sox Runline +1.5 (-146), Royals Runline -1.5 (+122), Total Over 9.5 (-107), Total Under 9.5 (-113)

The White Sox Can Win If…

The Chicago White Sox are coming off a recent game against the Kansas City Royals where they lost 3-1. Despite the loss, Lenyn Sosa hit a home run, showing his power at the plate. Miguel Vargas also had a solid performance with two hits, adding to the team’s offensive efforts.

The White Sox have some key stats that can help them win their next game. They rank 19th in home runs with 119, which shows they can hit for power. Their pitching staff has given up the 9th fewest home runs, which could keep the opposing team’s score low.

Starting pitcher Sean Burke will take the mound with an ERA of 4.26. He will aim to improve his record and keep the Royals’ hitters in check. With hitters like Edgar Quero and Lenyn Sosa in the lineup, the White Sox have the potential to put runs on the board.

The Royals Can Win If…

The Kansas City Royals are coming off a 3-1 win against the Chicago White Sox. In that game, Salvador Perez hit a home run and scored two runs. Noah Cameron pitched 5 1/3 innings, giving up just one run and striking out two batters.

The Royals have shown strong hitting stats this season. They rank third in doubles with 217 and tenth in stolen bases with 95. Their pitching has also been effective, with a team ERA of 3.64, ranking fourth in the league.

Key players like Bobby Witt Jr. and Vinnie Pasquantino are crucial for the Royals. Witt Jr. has a batting average of .290 and has scored 76 runs. Pasquantino leads the team with 22 home runs and 80 RBIs, making him a key player in today’s game.

The Lean

The Royals are favored with a moneyline of -166 against the White Sox at +140. The Royals have a stronger batting average and a better earned run average this season. My model projects the Royals to win with a score of 5-4, making them the pick for the moneyline.

The total for the game is set at 9.5 runs, with the over at -107 and the under at -113. Both teams have shown moderate hitting power, but the Royals’ pitching has been more effective. My model projects a total of 9 runs, so the recommendation is to take the under.

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Royals’ Historic Home Grip on Chicago

The Kansas City Royals’ dominance over the Chicago White Sox at Kauffman Stadium has reached rare territory. After Friday’s 3-1 win behind a Salvador Perez tiebreaking home run and rookie Noah Cameron’s strong outing into the sixth, Kansas City has outscored Chicago 59-13 during a 12-game home winning streak. The White Sox haven’t won in Kansas City since Sept. 6, 2023 and are 2-20 there since Aug. 10, 2022. As the Royals chase an American League wild-card spot, they’ve also won five of their past six at home overall. For a broader matchup breakdown and daily capsules, see the latest MLB previews at ScoresAndStats’ MLB game previews.

Pitching Matchup: Lorenzen Returns vs. Burke

Michael Lorenzen (5-8, 4.61 ERA) is slated for his first start since July 6 after a 15-day injured list stint for an oblique strain. In that last outing, he struck out seven over seven scoreless frames in a 4-0 win at Arizona. Following two rehab assignments, he says he feels back to full strength and will try to deepen a rotation that could manage his pitch count early.

Lorenzen’s track record against Chicago is strong: 2-0 with a 2.68 ERA in 10 career appearances (seven starts). Earlier this season, he worked six innings against the White Sox, allowing only a first-inning two-run homer with two walks and seven strikeouts in a 7-5 Kansas City win.

Chicago counters with Sean Burke (4-9, 4.26 ERA). In his lone career meeting with the Royals on May 6, he allowed only a solo shot by Kyle Isbel across 6 1/3 innings of a 4-3 loss in Kansas City. Recent form has been shakier: Burke is 0-2 with a 5.00 ERA over his last five starts and was limited to 3 1/3 innings last weekend despite throwing 88 pitches. He noted he “didn’t execute some pitches” and needs to work deeper into games.

Trends and Hot Bats to Watch

Bobby Witt Jr. is 0-for-3 against Burke but has been devastating against the White Sox overall, batting .531 (34-for-64) with 16 RBIs during a 16-game hitting streak versus Chicago. Isbel continues to trend up, hitting .395 in 12 games this month. For the White Sox, Lenyn Sosa has provided a jolt, batting .322 with six homers and 12 RBIs in his last 16 games; he has yet to face Lorenzen.

What It Means for Bettors

The combination of Kansas City’s sustained home edge, Lorenzen’s history against Chicago, and Burke’s recent efficiency concerns tilts the matchup toward the Royals, with the caveat of Lorenzen’s post-IL workload. If Burke finds early command, Chicago can keep it tight; otherwise, Kansas City’s contact-and-pressure profile plays well at home.

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Recent Form and How to Track It

Kansas City’s bullpen usage will be worth monitoring if Lorenzen’s pitch count is capped, while Chicago’s path hinges on Burke’s strike-throwing and run prevention early. Track how these trends evolve and verify outcomes with the most recent MLB game results.

Outlook

Given the Royals’ extreme home splits against the White Sox and Lorenzen’s favorable history, Kansas City holds the situational edge. Chicago’s route to an upset likely requires Burke repeating his May efficiency at Kauffman and Sosa sustaining his hot streak to provide timely power.

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