San Diego Padres vs Los Angeles Dodgers August 22nd 2025

The Los Angeles Dodgers will take on the San Diego Padres at PETCO Park. The game is set for Friday, August 22, 2025, at 9:40 PM. The Dodgers hold a record of 73-55 and are ranked first in the NL West. They are coming off a win and have split their last ten games.

The Padres are close behind with a 72-56 record, sitting second in the division. They are on a three-game winning streak and have won six of their last ten games. The weather forecast for the game predicts clear skies with a light breeze. Blake Snell will start for the Dodgers, while Yu Darvish will take the mound for the Padres.

Dodgers vs Padres Key Information

• Sport: Baseball
• Teams: Los Angeles Dodgers vs. San Diego Padres
• Venue: PETCO Park in San Diego, CA
• Date: Friday, August 22, 2025
• Betting Odds: Dodgers Moneyline -122, Padres Moneyline +103

The Dodgers Can Win If…

The Los Angeles Dodgers are coming off a strong win against the Colorado Rockies, taking the game 9-5. Clayton Kershaw pitched 5 2/3 innings, allowing three earned runs. Key hitters included Andy Pages, who went 2 for 4 with a home run, and Freddie Freeman, who added another homer and two RBIs.

The Dodgers have a solid lineup with Shohei Ohtani and Freddie Freeman leading the charge. Ohtani has 44 home runs, ranking third in the league, while Freeman holds a .303 batting average. The team ranks second in the league for slugging percentage and home runs, showing their power at the plate.

Pitching-wise, Blake Snell will start for the Dodgers with an impressive 1.80 ERA. The Dodgers’ pitching staff ranks fourth in strikeouts, which can challenge the Padres’ lineup. With these strengths, the Dodgers have a good chance to secure another win.

The Padres Can Win If…

The San Diego Padres are coming off a strong 8-4 win against the San Francisco Giants. In that game, Manny Machado led with 3 RBIs, while Fernando Tatis Jr. and Ramón Laureano each contributed with two hits. Starting pitcher Dylan Cease managed 7 strikeouts over 5 innings, allowing 4 earned runs.

The Padres have been solid at the plate, ranking 6th in batting average with .252. They have shown discipline, drawing 414 walks, which is 14th in the league. Their pitching has been even better, with a team ERA of 3.55, placing them 2nd, and they lead the league in batting average against at .224.

Key players like Manny Machado and Fernando Tatis Jr. are crucial for the Padres. Machado is hitting .294 with 21 home runs and 77 RBIs, while Tatis Jr. has a .268 average and 17 home runs. Yu Darvish will start on the mound, looking to improve his 5.97 ERA in this game against the Dodgers.

The Lean

The Dodgers are favored with a moneyline of -122 against the Padres at +103. The Dodgers have a strong pitching lineup, with a team ERA ranked 2nd in the league. My model projects a score of Dodgers 5, Padres 3. Based on these factors, the recommendation is to pick the Dodgers to win straight up.The total for the game is set at 8.0 runs, with both the over and under at -110. The Dodgers’ pitching staff has limited opponents’ batting average to .224, ranking 1st. Given the projected score of 5-3, the recommendation is to take the under for this game.

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Padres and Dodgers Battle in Final 2025 Regular-Season Series

The San Diego Padres and Los Angeles Dodgers are set for one final regular-season showdown this weekend, with the rivalry once again carrying major implications in the National League West race.

San Diego will host Los Angeles on Friday night in the opener of a three-game series at Petco Park, with both clubs fresh off victories and separated by just one game in the standings. Fans and bettors alike will have their eyes on this matchup, making it a prime spot for those following the latest MLB picks

Padres Enter with Renewed Momentum

The Padres arrive with confidence after taking three of four from the San Francisco Giants, including an 8-4 win on Thursday. The offense surged in the last three games of the series, outscoring San Francisco 21-6 to regain ground in the standings.

Manager Mike Shildt acknowledged the importance of rebounding after last weekend’s sweep in Los Angeles. “We competed well. Just couldn’t get on the good side of it,” Shildt said. “Really excited, can’t wait for Friday night. I wish it was tonight.”

For fans looking deeper into the matchup, the MLB previews section provides additional insights into pitching duels, team form, and betting angles.

Dodgers Maintain Slim Division Lead

The Dodgers enter the series holding a one-game lead over the Padres after salvaging a split against the Colorado Rockies. On Thursday, Los Angeles secured a 9-5 win by scoring in each of the first five innings, a reminder of their offensive depth.

Manager Dave Roberts was clear about his team’s mindset heading into San Diego. “We’ve obviously played well against those guys this year,” Roberts said. “They’re going to give us everything they have this weekend and we’ve got to be ready for it.”

Los Angeles already has the tiebreaker advantage secured, having won eight of the first ten meetings. For bettors evaluating the numbers, the MLB betting guide

highlights how season series records can impact playoff odds.

Pitching Matchup: Yu Darvish vs. Blake Snell

Friday’s opener features Yu Darvish (2-3, 5.97 ERA) for San Diego against Blake Snell (3-1, 1.80 ERA) for Los Angeles. Both starters faced off last weekend, with contrasting results.

Darvish allowed four runs over four innings in a 5-4 Padres loss and did not factor into the decision. Despite his struggles, he owns strong career numbers against the Dodgers, including a 2.55 ERA across 16 regular-season starts.

Snell, the 2023 NL Cy Young winner with San Diego, delivered six scoreless innings in a 6-0 Dodgers victory. His dominance against his former team has continued in 2025, posting a 0.82 ERA in two starts.

Fans looking to back expert selections on the pitching duel can explore premium options through buy picks from proven handicappers.

Rivalry Stakes in the NL West

Beyond the immediate standings, this weekend series represents a chance for the Padres to prove they can handle the Dodgers when it matters most. San Diego has fallen short in the head-to-head battle, but a strong showing would tighten the race and restore confidence.

The Dodgers, meanwhile, have a chance to extend their dominance while reinforcing their case as World Series contenders.

Handicapper performance has been a key factor for bettors tracking this rivalry all season long. The updated leaderboard shows which experts have been sharpest at identifying value in marquee matchups like Padres-Dodgers.

Series Outlook

With just one game separating the two teams, every inning will carry playoff implications. San Diego needs to protect home field, while Los Angeles looks to close out the season series with authority.

Baseball bettors and fans can follow live updates, recaps, and all the box score breakdowns on the MLB game results page