NFL Previews 
MLB Previews 
NBA Previews 
NHL Previews 
Soccer Previews 
Prediction 
Odds 
Last Recap 
Game Picks 
Top Handicapper 
Milwaukee Brewers vs St. Louis Cardinals September 12th 2025
The St. Louis Cardinals will take on the Milwaukee Brewers at American Family Field. The Cardinals have a record of 72-75, placing them 4th in the NL Central. They are currently on a three-game losing streak and have gone 4-6 in their last 10 games. Manager Oliver Marmol and his team will look to improve their road record of 31-41.
Get 5,000 Expert Picks for Just $9
Today Only!
The Brewers hold the top spot in the NL Central with a record of 89-58. They also have a three-game losing streak and a recent 4-6 record. Under Manager Pat Murphy, the Brewers have been strong at home with a 46-26 record. The game will start at 8:10 PM on Friday, September 12, 2025, and will be televised on FDSWI.
Cardinals vs Brewers Key Information
- Sport: Baseball
- Teams: St. Louis Cardinals vs. Milwaukee Brewers
- Venue: American Family Field in Milwaukee, WI
- Date: Friday, September 12, 2025
- Betting Odds: Cardinals Moneyline +155, Brewers Moneyline -185, Cardinals Runline +1.5 (-136), Brewers Runline -1.5 (+114), Total Over 8.5 (-106), Total Under 8.5 (-114)
Cardinals vs Brewers Picks and Predictions
The St. Louis Cardinals travel to face the Milwaukee Brewers in a critical NL Central matchup. Milwaukee leads the division and looks to rebound after being swept by Texas, while the Cardinals aim to claw their way back into the Wild Card hunt.
How the Cardinals Can Win
The Cardinals’ offense has shown flashes, with Thomas Saggese going 4-for-5 and Iván Herrera blasting a home run in their recent loss to Seattle. St. Louis ranks 10th in doubles (234), giving them the ability to produce extra-base hits. Alec Burleson (.282) and Willson Contreras (20 HRs) remain reliable offensive threats.
On the mound, Andre Pallante must step up despite carrying a 5.28 ERA. If he can find consistency and limit Milwaukee’s patient hitters, St. Louis could steal a much-needed divisional win.
How the Brewers Can Win
The Brewers’ 6-3 loss to Texas showed both their offensive depth and pitching inconsistency. Brice Turang and Jackson Chourio each homered, while Freddy Peralta struck out nine. Milwaukee’s bats have been hot all year, ranking 2nd in batting average (.260) and 2nd in OBP (.331).
Quinn Priester is the key. The right-hander has been outstanding at 12-2 with a 3.25 ERA. Milwaukee has won 17 straight games he’s pitched in, showcasing how much confidence the team has when he takes the mound.
Cardinals vs Brewers: Key Stats
| Category | Cardinals | Brewers |
|---|---|---|
| Record | 72-75 | 89-58 |
| Team ERA | 4.38 (20th) | 3.63 (2nd) |
| Batting Avg. | .245 (17th) | .260 (2nd) |
| Home Runs | 174 (21st) | 190 (11th) |
| Doubles | 234 (10th) | 239 (8th) |
Betting Odds and Line Movement
According to the latest MLB odds:
| Team | Moneyline | Spread | Total |
|---|---|---|---|
| Cardinals | +155 | +1.5 (-120) | O 8.5 (-106) |
| Brewers | -185 | -1.5 (+100) | U 8.5 (-114) |
The Brewers are strong favorites, backed by their elite pitching and on-base skills.
Matchup Breakdown
- Pitching Edge: Quinn Priester has won 11 consecutive decisions, while Andre Pallante is 0-6 with a 7.64 ERA over his last seven starts.
- Offensive Depth: The Brewers rank top-10 in nearly every hitting metric, while the Cardinals continue to struggle with consistency.
- Division Impact: Milwaukee has a 5.5-game NL Central lead, while St. Louis is slipping further back in the Wild Card race.
For bettors, this projects as a Brewers -1.5 run line play with value on the under 8.5 given Milwaukee’s pitching dominance.
Cardinals vs Brewers Prediction
Milwaukee should bounce back quickly after the Rangers sweep. Priester’s dominance, combined with a patient and powerful lineup, puts the Brewers in position to handle Pallante and the Cardinals’ struggling bullpen.
For more expert breakdowns, visit our MLB picks page.
