San Francisco Giants vs Los Angeles Dodgers Picks and Predictions September 12th 2025

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San Francisco Giants vs Los Angeles Dodgers September 12th 2025

The Los Angeles Dodgers will visit the San Francisco Giants at Oracle Park on Friday night. The Dodgers hold a record of 82-64 and are first in the NL West. They are on a four-game winning streak. The Giants, with a record of 74-72, rank third in the division and have won seven of their last ten games.

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Yoshinobu Yamamoto will start for the Dodgers with an ERA of 2.72. Justin Verlander will pitch for the Giants, holding an ERA of 4.09. The game will be broadcast on SN LA at 10:15 PM. The weather forecast predicts mild conditions with a light breeze and few clouds.

Dodgers vs Giants Key Information

  • Sport: Baseball
  • Teams: Los Angeles Dodgers vs. San Francisco Giants
  • Venue: Oracle Park in San Francisco, CA
  • Date: Friday, September 12, 2025
  • Betting Odds: Dodgers Moneyline -156, Giants Moneyline +132, Dodgers Runline -1.5 (+109), Giants Runline +1.5 (-131), Total Over 7.5 (-115), Total Under 7.5 (-105)

Los Angeles Dodgers vs San Francisco Giants Picks and Predictions

The Los Angeles Dodgers and San Francisco Giants renew their rivalry in a crucial three-game NL West set. The Dodgers are riding momentum after a four-game win streak, while the Giants remain alive in the wild-card race.

The Dodgers Can Win If…

Los Angeles crushed Colorado 9-0 in their last outing, with Blake Snell throwing six scoreless innings and Mookie Betts driving in five runs on a 4-for-5 night. The Dodgers rank second in MLB in slugging and home runs, with Betts, Shohei Ohtani, and Freddie Freeman anchoring a relentless lineup.

Yoshinobu Yamamoto (11-8, 2.72 ERA) gets the ball and has been dominant, nearly no-hitting Baltimore in his last outing. If Yamamoto commands the game early and the Dodgers’ offense continues to attack, Los Angeles is in prime position to extend its lead in the division.

Dodgers Snapshot

CategoryStatLeague Rank
Record86-591st in NL West
Slugging %.4562nd
Home Runs2422nd
SP Yamamoto2.72 ERA11-8 record

The Giants Can Win If…

San Francisco is coming off a 5-3 loss to Arizona but has gone 13-4 since late August to climb back into the playoff picture. Casey Schmitt and Rafael Devers have been catalysts, with Devers batting .333 and driving in 18 runs over his last 14 games.

Veteran ace Justin Verlander (3-10, 4.09 ERA) starts for the Giants. Though inconsistent this season, Verlander has pitched well historically against the Dodgers. Backed by a staff that ranks sixth in ERA, the Giants can make this a grinder if Verlander holds up against LA’s deep order.

Giants Snapshot

CategoryStatLeague Rank
Record78-672nd in NL West
Team ERA3.786th
HRs18014th
SP Verlander4.09 ERA3-10 record

Matchups and Betting Outlook

This game pits Yamamoto’s control and strikeout ability against Verlander’s veteran guile. The Dodgers’ slugging advantage is clear, but San Francisco’s bullpen and timely hitting could keep the game close.

Oddsmakers have the Dodgers at -156 and the Giants at +132, with a total of 7.5 runs. Bettors can monitor shifts on the live MLB odds board, as rivalry games often draw sharp action.

Series History and Context

The Dodgers lead the NL West by three games, with seven head-to-head matchups against the Giants still to come. Los Angeles has rebounded from a rocky road trip with four straight wins, while the Giants are chasing a wild-card berth. Expect playoff-like intensity, with Betts, Ohtani, and Freeman on one side and Devers and Adames on the other.

Picks and Predictions

Projection: Dodgers 5, Giants 3. Yamamoto’s form and the Dodgers’ offensive depth give Los Angeles the edge. The model also leans to the over 7.5 (-115), with both lineups capable of run bursts.

For more breakdowns and betting projections, check the expert MLB picks hub.