Miami Marlins vs Detroit Tigers Picks and Predictions September 12th 2025

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The Detroit Tigers, with a record of 84-63, are set to play against the Miami Marlins at loanDepot Park. The Tigers lead the AL Central, but they are coming off a loss. Their recent form shows a balanced 5-5 in their last ten games. Tarik Skubal will start on the mound for the Tigers. He has an ERA of 2.10 and a WHIP of 0.86, with a 13-4 win-loss record.

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The Miami Marlins hold a 68-79 record and are third in the NL East. They have won their last two games but have struggled recently, going 3-7 in their last ten. Sandy Alcantara will pitch for the Marlins. He has an ERA of 5.67 and a WHIP of 1.32, with an 8-12 win-loss record. The game will be played under a retractable roof, so weather conditions are unlikely to affect play.

Tigers vs Marlins Key Information

  • Sport: Baseball
  • Teams: Detroit Tigers vs. Miami Marlins
  • Venue: loanDepot Park in Miami, FL
  • Date: Friday, September 12, 2025
  • Betting Odds: Tigers Moneyline -206, Marlins Moneyline +174, Tigers Runline -1.5 (-115), Marlins Runline +1.5 (-105), Total Over 7.0 (+102), Total Under 7.0 (-123)

Detroit Tigers vs Miami Marlins Picks and Predictions

The Detroit Tigers head to Florida on Friday night to face the Miami Marlins in the opener of a three-game set. Detroit is closing in on its first AL Central title since 2014, while Miami is simply looking to play spoiler with a Cy Young showdown on the mound.

The Tigers Can Win If…

Detroit comes in looking to bounce back from a 9-3 loss to the Yankees, but this team has proven it can hit. With a .251 batting average (6th in MLB) and 185 home runs on the season, the Tigers bring both contact and power. Spencer Torkelson has delivered 28 homers, while Riley Greene leads the club with 33. Add Dillon Dingler’s recent power surge, and the Tigers can string runs together quickly.

The real edge, however, is Tarik Skubal. The 2024 AL Cy Young winner has only gotten better, entering this game with a sparkling 2.10 ERA and 0.86 WHIP. He threw seven shutout innings in his last start against the White Sox and continues to dominate with 222 strikeouts this year. Against a Marlins team that struggles to put runs on the board consistently, Skubal is positioned to take control of this matchup.

The Marlins Can Win If…

Miami just blanked Washington 5-0 and has quietly won back-to-back games, with its pitchers striking out 22 batters without issuing a walk. Eric Wagaman powered the lineup in that win, driving in three runs, while Jakob Marsee continues to shine with a .340 average. The Marlins rank 5th in doubles with 246 and 7th in batting average at .250, showing they can chip away with extra-base hits.

The concern is Sandy Alcantara. The 2022 NL Cy Young winner has struggled most of this season with a 5.67 ERA, but his experience remains valuable. He posted a 3.69 ERA in August, his best month of 2025, and if he can build on that progress, Miami has a chance. The bullpen also looks sharper of late, giving the Marlins an outside shot if they can scratch out early runs.

Key Stats Breakdown

CategoryTigersMarlins
Team Batting Avg.251 (6th).250 (7th)
Home Runs185 (12th)164 (18th)
Team ERA3.77 (9th)4.63 (24th)
Opponent Avg.228 (2nd).260 (26th)
Doubles219246 (5th)

Betting Lean and Projection

The Tigers are heavy favorites at -206, while the Marlins sit at +174. Detroit holds the edge in pitching and overall consistency, and Skubal’s presence on the mound tips the scale. Our model projects a Tigers 5, Marlins 3 final, making Detroit the recommended moneyline pick.

The total is set at 7 runs. With both teams ranking top 10 in batting average and doubles, there’s potential for more offense than expected. The projection calls for 8 combined runs, so the over 7 (+102) carries more value. For more updated numbers, check the MLB odds board.

Series Outlook

This matchup is a rare clash of Cy Young winners at very different stages. Skubal has emerged as one of the game’s best arms, while Alcantara is still searching for his old form after Tommy John surgery. Detroit’s magic number to clinch the AL Central is down to eight, and every win matters as they try to secure their first division crown in over a decade.

Miami, meanwhile, has nothing to lose. The Marlins can’t climb into contention, but they can play spoiler against a playoff-bound Tigers team. Expect a playoff-like intensity with both aces on the mound. For more coverage and daily breakdowns, visit the MLB picks hub.