The Houston Astros will play against the Athletics at Sutter Health Park in West Sacramento, CA. The game is set for Tuesday, September 23, 2025, at 10:05 PM. The Astros have an 84-72 record and are second in the AL West. However, they are on a three-game losing streak and are 5-5 in their last ten games.

The Athletics, with a 73-83 record, sit fourth in the AL West. They have lost their last two games but have gone 7-3 in their last ten. The weather forecast predicts a very hot day with clear skies and a light crosswind. Fans can catch the game on SCHN.

Astros vs Athletics Key Information

• Sport: Baseball
• Teams: Houston Astros vs. Athletics
• Venue: Sutter Health Park in West Sacramento, CA
• Date: Tuesday, September 23, 2025
• Betting Odds: Astros Moneyline -112, Athletics Moneyline -106, Astros Runline -1.5 (+141), Athletics Runline +1.5 (-170), Total Over 10.0 (-117), Total Under 10.0 (-103)

The Astros Can Win If…

The Houston Astros are coming off a recent 7-3 loss to the Seattle Mariners. Despite the loss, key players like Jose Altuve and Zach Cole showed strong performances. Altuve went 2-for-3 with a double and an RBI, while Cole hit a home run, contributing to the Astros’ seven hits in the game.

The Astros have several stats that show why they can win. They rank 8th in the league with a .251 batting average and have hit 172 home runs this season. Their pitching also stands out, with a batting average against of .232, ranking them 5th in the league.

Key players for the Astros include Jeremy Peña and Christian Walker. Peña boasts a .304 batting average, while Walker leads the team with 23 home runs. With Cristian Javier on the mound, who has a WHIP of 1.24, the Astros have a solid chance to secure a win against the Athletics.

The Athletics Can Win If…

The Athletics recently struggled against the Pirates, losing 11-0. Despite the loss, Brent Rooker and Brett Harris showed some promise at the plate. Rooker went 2-for-4, while Harris hit a double in his only at-bat.

The Athletics have some strong stats that show they can win. They rank 4th in slugging percentage at .432 and 3rd in doubles with 281 this season. Their ability to hit for power gives them a chance to score runs quickly.

In their upcoming game, Jeffrey Springs will start for the Athletics. Springs has a solid ERA of 4.17 and a WHIP of 1.22, which gives them a good chance on the mound. With a lineup featuring Nick Kurtz and Tyler Soderstrom, the team has the firepower to support Springs and secure a win.

Latest Betting Trends

• Houston is 2-5 in its last seven games overall.
• The Astros are 6-3 in their last nine road games against the Athletics.
• Oakland has won seven of its last 10 games but is just 3-6 in its last nine home contests.
• The Athletics are 4-1 in their last five series openers.
• The Under has hit in five of Houston’s last seven games.
• The Over is 6-2 in the last eight head-to-head matchups between Houston and Oakland.

The Lean

The Astros are slightly favored with a moneyline of -112. The Athletics have a moneyline of -106, making this a close call. The Astros have a better pitching staff, ranking 11th in ERA and 5th in batting average against. Our model projects the Astros to win 6-4. Therefore, the recommendation is to pick the Astros to win straight up.

The total for the game is set at 10.0 runs. The Astros’ strong pitching and the Athletics’ lower batting average suggest a lower scoring game. Our model projects a total score of 10 runs. Given this, the recommendation is to take the under at 10.0 (-103).

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Reeling Astros Must Recover Against Athletics

The Houston Astros were 20 games above .500 on July 6 and looked destined for their ninth consecutive playoff berth. Now, with just six games left in the regular season, Houston finds itself in a desperate fight to keep that streak alive.

The Astros (84-72) open a critical six-game West Coast road trip on Tuesday night against the Oakland Athletics in West Sacramento, before heading to Anaheim for three games with the Angels. Both Oakland and Los Angeles have been eliminated from postseason contention, but Houston cannot afford any slip-ups with so much at stake.

Astros Fighting for Playoff Survival

Houston was just swept at home by the Seattle Mariners, a series in which they were outscored 17-7. The Mariners not only lead the Astros by three games in the American League West, but they also hold the all-important tiebreaker. That means Houston’s most realistic path to October runs through the AL wild card.

Competition is tight, with the Boston Red Sox, Cleveland Guardians, and Detroit Tigers also battling for the final two wild-card spots. Either Cleveland or Detroit will secure the AL Central crown, making Houston’s margin for error even thinner.

Manager Joe Espada emphasized his team’s urgency after the sweep. “We’ve got six to go, six big ones. We played really well on the West Coast. We need to bring it, man. This is crunch time. This is when you play your best,” Espada said.

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Key Players and Injuries

Shortstop Jeremy Peña’s status is uncertain due to an oblique injury that forced him to miss Sunday’s game. The Astros will need contributions from stars like Peña, along with veteran leadership to steady the lineup.

Infielder Carlos Correa summed up the team’s approach heading into the final week. “We have to go out there and figure out a way to win, no matter if it’s pretty or ugly,” he said. “At the end of the day, it’s about the W at the end.”

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Oakland Looking to Play Spoiler

The Athletics (73-83) may be out of the postseason picture, but they have the pieces to disrupt Houston’s plans. Oakland recently won seven of eight before dropping back-to-back shutouts to the Pittsburgh Pirates.

The A’s feature a trio of power hitters, with rookie Nick Kurtz slugging 33 home runs, Shea Langeliers adding 30, and All-Star Brent Rooker posting 30 homers, 40 doubles, and 87 RBIs. Rooker is also chasing a 162-game season, which would place him in rare company in franchise history.

Find more team-by-team analysis on the MLB game results page

Pitching Matchup

Houston hands the ball to Cristian Javier (2-3, 4.45 ERA), who recently ended a five-game winless stretch by defeating the Texas Rangers. Javier has a 3.92 ERA across 14 career appearances against Oakland, making him a steady option in this must-win spot.

For the Athletics, left-hander Jeffrey Springs (10-11, 4.17 ERA) will take the mound. Springs is winless in his last eight starts but has had success against Houston, beating them earlier this season and owning a 2-0 career record against the Astros.