Boston College Eagles vs Clemson Tigers Picks and Predictions October 11th 2025

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Clemson vs Boston College – Week 7 ACC Betting Preview

The Clemson Tigers continue their so-called “Patriots Tour” as they visit the Boston College Eagles in Chestnut Hill. Dabo Swinney’s team comes in at 2-3 (1-2 ACC) after a dominant 38-10 win over North Carolina, while Boston College sits at 1-4 (0-3) and reeling from a 48-7 loss at Pitt.

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Clemson has won 12 straight in the head-to-head series and hasn’t lost to a team with a losing record since 2010 — the last time Boston College beat them.

Clemson can win if

Cade Klubnik repeats his performance from last week. Against North Carolina, he went 22-for-24 for 254 yards and four touchdowns, easily his cleanest game of the year. The Tigers scored on their first four possessions, setting an early tone that erased recent offensive concerns.

The passing chemistry between Klubnik and Adam Randall, who caught two touchdowns, gives Clemson more balance alongside its ground game. The defense remains the foundation, holding opponents to under 290 yards per game and ranking top 20 nationally in sacks.

If Clemson plays clean football — no early turnovers and controlled tempo — the Tigers’ streak over the Eagles should extend to 13 straight.

Boston College can win if

They protect the quarterback and establish any semblance of a run game. Boston College managed only 27 rushing yards at Pitt and has been under 100 in four of five games this season. That imbalance forces Alabama transfer Dylan Lonergan into pressure-heavy passing downs, where he has taken multiple sacks.

The Eagles rank 11th nationally in passing offense (313.4 yards per game), but their offensive line must give Lonergan time. On defense, Boston College has been hit hard by injuries. Still, KP Price and Omar Thornton combined for 20 tackles last week, giving the Eagles some physicality at the second level.

If the Eagles can slow Clemson’s tempo early and hit explosive plays in the air, they have a shot to cover at home.

Line Movement and Odds

Opening: Clemson -13.5 / Boston College +13.5
Current: Clemson -14 / Boston College +14
Total: 50.5 points (Over -110 / Under -110)

Early action has leaned toward Clemson after their convincing win over North Carolina. Track live movement and splits on the college football odds page.

Matchup Breakdown

Clemson’s defense remains one of the ACC’s most efficient, ranking top 10 in yards allowed per play. Their front four, led by Peter Woods and TJ Parker, should dominate the trenches against a Boston College team that’s struggled to protect the quarterback.

Boston College has shown flashes through the air, but its defense ranks bottom 30 nationally in total yards allowed. The Eagles will need turnovers or special teams help to stay competitive.

Compare advanced stats and depth charts for both programs on the college football teams page. For betting guidance, visit the college football betting guide and strategy resources in the Bettors Handbook.

Injuries and Conditions

Clemson Tigers

  • WR Antonio Williams (ankle) – questionable
  • LB Barrett Carter (knee) – out

Boston College Eagles

  • DE Quintayvious Hutchins (ankle) – doubtful
  • LB Bryce Steele (knee) – out

Weather in Chestnut Hill should be clear with light winds and temperatures around 55°F — good conditions for passing.

Best Bets and Prediction

Clemson’s offense is finally clicking, and Boston College’s injuries on defense make this matchup difficult to manage. Expect Clemson to strike early again and control the pace through the air.

Prediction: Clemson 38, Boston College 17
Best Bet: Clemson -14 (-110)
Secondary Lean: Over 50.5 (-110)

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