San Antonio Spurs vs Memphis Grizzlies Picks and Predictions November 18th 2025

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The San Antonio Spurs host the Memphis Grizzlies at Frost Bank Center in NBA Cup play. San Antonio enters at 7-7 after a win over Sacramento, while Memphis sits at 4-10 following a loss to Cleveland. Bettors will weigh the Spurs’ depth without Victor Wembanyama against the Grizzlies’ struggles without Ja Morant.

Line Movement and Odds

  • Spurs Spread: -6.5 (-110)
  • Grizzlies Spread: +6.5 (-110)
  • Spurs MoneyLine: -245
  • Grizzlies MoneyLine: +200
  • Total: 223.5

San Antonio opened as a moderate home favorite, reflecting Memphis’ injuries and recent skid. See full NBA odds for market movement.

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Matchup Breakdown

San Antonio Spurs Outlook

Victor Wembanyama (calf) is sidelined, removing the Spurs’ leading scorer and rebounder. Stephon Castle (hip) is questionable, leaving San Antonio reliant on depth. De’Aaron Fox scored 28 with 11 assists in the win over Sacramento, while Harrison Barnes added 20. The Spurs had seven players in double figures, showcasing balance. San Antonio ranks top-10 in rebounding and blocks, even without Wembanyama.

Memphis Grizzlies Outlook

Ja Morant (calf) is out for at least two weeks, joining multiple injured guards. Jaren Jackson Jr. scored 26 in the loss to Cleveland, while Santi Aldama added a double-double. Zach Edey debuted with 13 points, providing rim protection. Memphis has dropped four straight and eight of nine, struggling offensively without Morant’s playmaking. Their defense remains inconsistent, especially late in games.

Key Matchup / Path to Victory

The Spurs must rely on Fox and Barnes to drive offense while maintaining defensive intensity. The Grizzlies need Jackson Jr. to carry scoring and Edey to anchor the paint. Depth and late-game execution will determine whether Memphis can stay competitive.

Injuries / Availability

San Antonio lists Victor Wembanyama (calf) as out and Stephon Castle (hip) as questionable. For full player status, check the Spurs injury report.

Memphis lists Ja Morant (calf), Scotty Pippen Jr. (toe), Ty Jerome (calf), and Javon Small (toe) as out. See the Grizzlies injury page for latest updates.

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Environment

The game tips at Frost Bank Center, where San Antonio is 5-3 at home. Memphis is 1-6 on the road, struggling outside FedExForum. Expect San Antonio’s depth to thrive at home, while Memphis leans on Jackson Jr. to keep pace.

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Best Bets and Prediction

Projected Final Score: Spurs 115, Grizzlies 107

  • Best Bet: Spurs -6.5
    San Antonio’s depth and Memphis’ guard injuries give them value to cover at home.
  • Total: Under 223.5
    Our model projects 222 points, leaning under given both teams’ injury-related scoring limitations.

San Antonio’s balance should secure the win, but Memphis’ frontcourt gives them a chance to compete. Expect a slower-paced game that trends under the total.

Handicappers and Service Plays

For sharper betting insights on this Western Conference clash, explore our Best Handicappers, track performance on the Leaderboard, and check the Buy Picks section for expert-backed selections.

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