Memphis Tigers vs Vanderbilt Commodores Picks and Predictions December 17th 2025

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Vanderbilt Commodores vs Memphis Tigers Betting Preview

Vanderbilt puts its perfect 10-0 record on the line Wednesday night in Memphis as the Commodores revive an in-state rivalry that has been dormant for most of the past two decades. Mark Byington wanted this matchup, even agreeing to open the series on the road. You can track updated pricing and movement on the NCAA basketball odds page as tipoff approaches.

The Commodores are ranked No. 13 and have handled business so far, though Byington was not pleased with the overall effort in an 83-72 win over Central Arkansas. Tyler Nickel carried the offense with a career-high 30 points and eight made threes, but Vanderbilt knows that level of balance must improve against a more athletic opponent.

Memphis enters at 4-5 and looking to reset after a rough outing at Louisville. The Tigers surrendered 18 three-pointers and never found rhythm in a 99-73 loss. Penny Hardaway emphasized execution and discipline, two areas that have fluctuated this season. Protecting home court becomes the immediate focus.

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Line Movement and Odds

Vanderbilt opens as a modest favorite despite playing on the road, a reflection of its unbeaten start and defensive efficiency. Totals sit in a mid-range window, balancing Vanderbilt’s pace against Memphis’ athletic scoring potential. Bettors are weighing Vanderbilt’s consistency against Memphis’ urgency at home.

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Matchup Breakdown

Vanderbilt wins with spacing and shot discipline. Nickel’s breakout adds another perimeter weapon, but the Commodores rely on ball movement and defensive containment more than volume shooting. When they avoid extended scoring droughts, they control tempo.

Memphis must clean up defensive rotations. Miscommunication burned the Tigers at Louisville, especially on the perimeter. Hasan Abdul Hakim provided a bright spot with 18 points, but the offense stalled once possessions broke down into isolation. Memphis needs downhill pressure and cleaner execution to test Vanderbilt’s defense.

For market consensus and supporting angles, the free college basketball picks section helps frame expectations.

Injuries and Conditions

Vanderbilt

No new injuries reported.
Full details: Vanderbilt team page

Memphis

No new injuries reported.
Full details: Memphis team page

Indoor matchup, no weather considerations.

Best Bets and Prediction

Vanderbilt’s discipline and defensive structure give it an edge, but Memphis’ athleticism keeps this competitive, especially at home. Execution late will decide it.

Projected Score: Vanderbilt 76, Memphis 71
Best Bet: Vanderbilt ATS
Secondary Lean: Under, tied to Vanderbilt’s pace control

For matchup-based betting fundamentals and situational angles, use the Bettors Handbook.

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