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Dayton heads to Philadelphia to face La Salle on Wednesday, January 21, 2026 at 6:30 PM ET at John Glaser Arena. This Atlantic 10 conference game will be streamed on ESPN+. Dayton comes in at 14-4 and has looked like one of the steadier teams in the league, while La Salle is 6-13 but has been more competitive at home with a 5-3 record.
Dayton is laying 10.5 with a total of 135.5. That’s a pretty clear market opinion: Dayton’s offense and physicality should travel, but this isn’t expected to be a track meet. The handicap is really about whether La Salle’s home shooting and energy can keep this within two possessions, or whether Dayton’s pressure at the line and overall efficiency eventually stretches it.
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Dayton Flyers vs La Salle Explorers Odds
These are the current betting lines, and bettors should always monitor updated numbers and shop for the best number on the latest college basketball odds.
| Team | Moneyline | Spread | Total |
|---|---|---|---|
| Dayton Flyers | -625 | -10.5 (-105) | O 135.5 |
| La Salle Explorers | +455 | +10.5 (-115) | U 135.5 |
Grand Canyon Antelopes
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San Diego St Aztecs
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Jan 21, 2026 23:00 EST
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+1.00 -106
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-1.00 -106
o+143.50-108
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u+143.50-108
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USC Trojans
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Northwestern Wildcats
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Jan 21, 2026 23:00 EST
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o+154.00-108
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u+154.00-108
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Saint Mary’s Gaels
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Oregon St Beavers
Open
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Jan 21, 2026 23:00 EST
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-17.50 -106
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+17.50 -106
o+142.00-108
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u+142.00-108
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Dayton Flyers Betting Form
Dayton is coming off a 78-51 win over Loyola Chicago, and it was the kind of game you like to see from a road favorite profile. They defended, they didn’t give away possessions, and the offense got contributions from multiple spots. Javon Bennett and De’Shayne Montgomery combining for 40 is a good sign because it means Dayton didn’t need a one-man show to create separation.
The biggest betting lever for Dayton is free throws. They rank 7th nationally in free throws made per game and they hit 75.6% at the stripe, which is huge when you’re laying numbers like -10.5. It gives Dayton a way to keep scoring even when the half-court offense goes quiet for a few minutes. It also tends to travel well, because getting to the line is often about physicality and shot selection more than shooting luck. If you’re checking how Dayton has been trending in recent games and how they’ve performed in similar favorite spots, the Dayton schedule and stats hub keeps it organized.
La Salle Explorers Betting Form
La Salle just beat St. Bonaventure 78-74 and shot 58.1% from the field, which is not something you can bank on, but it’s still meaningful. Jerome Brewer Jr. going for 27 on a perfect shooting night is the type of performance that can flip a spread outcome even if the matchup is bad on paper. Jaeden Marshall adding 23 matters too, because for La Salle to stay inside +10.5, it needs multiple scoring options to hit.
The home record is the real reason this line isn’t larger. La Salle is 5-3 at John Glaser Arena and they tend to play with better pace and confidence there. If they can get early offense and avoid long empty stretches, the crowd and energy can keep the game uncomfortable. The problem is that La Salle’s offensive floor is low. When the jumpers don’t go, it can be a grind to reach the high 60s, and that’s tough against a team like Dayton that can score without needing to shoot great.
Dayton Flyers vs La Salle Explorers Matchup Breakdown
This matchup shapes up like a favorite side that can win the possession battle. Dayton’s ability to get to the free-throw line is a problem for an underdog that wants to keep things slow and controlled. Fouls extend games and they create points without the clock moving, which is the opposite of what La Salle needs when it’s catching double digits.
The other key is shot quality. Dayton doesn’t need to run to score, but it can punish bad possessions quickly if La Salle starts forcing contested shots. That’s usually how these spreads break. The underdog hangs around, then there’s a five-minute stretch of empty trips, and suddenly it’s 12 instead of 4. La Salle’s best shot is to keep its shot selection disciplined, keep Dayton out of transition, and make Dayton play in the half court without free points at the line.
The total at 135.5 is interesting because it’s relatively modest compared to most of the other games you’ve sent. That suggests the market expects a slower game, maybe a lower La Salle output. If Dayton is in control, you can get a second half where they’re managing the game and living at the stripe, which can still cash an Under if La Salle’s offense stalls. Thinking about those scripts matters more than points per game averages. The sports betting strategy guide has a useful framework for that, especially for large spread games where the end of the game can play differently than the first 30 minutes.
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Dayton Flyers vs La Salle Explorers Predictions and Best Bets
I lean Dayton -10.5. Dayton is the better team, and more importantly, it has a style that tends to cover when it’s locked in. Free throws travel. Defense travels. And Dayton has been winning as a favorite all year. La Salle’s home edge is real, but it’s not the type of edge that consistently holds up when the opponent can generate points at the line and can defend without fouling.
On the total, I lean Under 135.5. La Salle needs a good shooting night to push this into the 140s, and that’s a tough ask against a disciplined defense. Dayton can still score enough to cover while the game stays under if La Salle lands in the mid 60s. The main risk is if La Salle’s home shooting shows up again and Dayton’s free throws extend the scoring late.
Best Bet: Under 135.5.
NCAAB Picks and Handicappers on ScoresAndStats
A-10 games are often priced tightly because familiarity is high and the styles can clash, which is where bettors can find better numbers if they’re willing to focus on matchups rather than resumes. The best approach is usually building a card, comparing angles, and staying disciplined about price.
ScoresAndStats makes that easier with today’s college basketball picks, so you can compare spread and total leans across the slate and see where different betting styles line up. If you’re moving between games and want a quick place to track teams while you shop numbers, the NCAAB teams page is a clean hub for schedules and results.
