Indiana Hoosiers vs Purdue Boilermakers Picks and Predictions January 27th 2026

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The No. 4 Purdue Boilermakers head to Bloomington to face the Indiana Hoosiers in a heated Big Ten rivalry. Purdue is looking to regain its shooting rhythm and rebounding dominance after consecutive losses, while Indiana snapped a four-game skid with a convincing win over Rutgers. With both teams motivated and the rivalry atmosphere in full swing, this matchup highlights a battle between Purdue’s efficiency and Indiana’s resurgent confidence.

Line Movement and Odds

Purdue enters as the favorite, but Indiana’s home-court energy makes this line worth monitoring. Current market:

  • Purdue Spread: -6.5 (-110)
  • Indiana Spread: +6.5 (-110)
  • Purdue MoneyLine: -250
  • Indiana MoneyLine: +200
  • Total: 150.5 (-110)

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Matchup Breakdown

Purdue Outlook

The Boilermakers average 79.2 points per game, with Braden Smith, Fletcher Loyer, Trey Kaufman-Renn, and Oscar Cluff leading the offense. Smith’s 27 points and 12 assists vs Illinois highlighted his playmaking, while Loyer and Kaufman-Renn provide balanced scoring. Purdue’s efficiency (17-3 overall record; 7-2 Big Ten; 38.3% three-point shooting on the season) underscores their strengths. Their ability to shoot from deep and dominate the boards makes them dangerous, though recent lapses have cost them.

Indiana Outlook

The Hoosiers average 74.1 points per game, with Lamar Wilkerson, Nick Dorn, and Tucker DeVries driving production. Wilkerson’s 27 points vs Rutgers highlighted his consistency, while Dorn’s six threes showcased his perimeter shooting. Indiana’s efficiency (13-7 overall record; 4-5 Big Ten; improved rebounding in last outing) underscores their strengths. Their ability to shoot from deep and defend better gives them a chance to stay competitive.

Key Factors

This matchup may hinge on three-point shooting and rebounding. Purdue must regain its perimeter accuracy and control the boards, while Indiana must rely on Wilkerson’s scoring and Dorn’s perimeter shooting to tilt the game. Execution in the final minutes will likely decide the margin.

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Injuries / Availability

Purdue: The Boilermakers report no fresh injury concerns heading into Tuesday’s contest.

Indiana: Tayton Conerway continues to play through an ankle injury but is expected to be available.

Environment

Simon Skjodt Assembly Hall has been a tough venue for visiting teams, and Indiana will look to use its home crowd to fuel momentum. Purdue, however, enters with top-five pedigree and motivation to bounce back, making this a clash of home resilience versus visiting firepower.

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Best Bets and Prediction

Projected Final Score: Purdue 82, Indiana 75

  • Purdue -6.5 → Best Bet. Their shooting depth and rebounding edge suggest they can cover the spread.
  • Over 150.5 → Total play. Both teams’ offensive pace points toward a combined score above the line.

Purdue’s depth and shooting should carry them to victory, while Indiana’s offense keeps the spread in play. Expect a high-scoring contest with totals landing just over the posted number.

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