Chicago Cubs vs Arizona Diamondbacks Picks and Predictions May 3rd 2026

Cubs eager to continue home dominance in clash vs. D-backs

The Chicago Cubs will turn to left-hander Matthew Boyd in an attempt to sweep the Arizona Diamondbacks on Sunday afternoon and bump their home winning streak to 11 games.

Winners of 14 of their last 17 games overall and 13-5 at home this season, the Cubs secured a series win with a 2-0 triumph on Saturday. Behind starter Shota Imanaga’s seven scoreless innings, Ben Brown became Chicago’s seventh reliever to record a save this season.

“You play the game in front of you and play with the guys you have and then you go from there,” Cubs manager Craig Counsell said about a series of injuries that have put pitchers into new roles.

“That builds resiliency, if anything.”

Boyd (1-1, 7.00 ERA) will oppose Diamondbacks right-hander Merrill Kelly (1-2, 9.20) in a matchup of rotation stalwarts who have yet to find their footing in a season disrupted by injury.

Boyd, the Cubs’ Opening Day starter, struck out 10 in a 6-2 victory over the Los Angeles Angels in his second start of the season on April 1. He reported slight arm discomfort, however, and the Cubs placed him on the injured list with a left biceps strain as a precaution.

He returned to the rotation on April 22 and since has made two starts, although he has not made it through five innings in either one. He notched a no-decision against both Philadelphia and San Diego in which he gave up seven runs on 13 hits in 8 2/3 innings.

Boyd was irked at himself for a failed ABS challenge in the first inning of his latest outing, the Cubs’ 9-7 loss at San Diego on Monday.

He called for a review on the fourth pitch of the first inning — a 2-1 fastball to leadoff hitter Ramon Laureano that was shown to be a ball. The Padres used two walks and three hits to score three runs that inning.

“It’s putting our hitters and our team in a hole when you do something like that in that situation, so early in the game,” Boyd said. “It was not a smart move on my part. I regretted it. I’ll do my best to not make that mistake again.”

The Cubs rallied to take a 5-3 lead into the last of the third inning but could not hold on.

Boyd is 0-2 with a 4.50 ERA in three career starts against the Diamondbacks, the most recent a no-decision in which he gave up four hits over five scoreless innings in a 10-6 loss in Arizona on March 30, 2025. Ketel Marte is 2-for-5 against him.

Kelly opened the season on the injured list with intercostal nerve irritation, which caused mid-back tightness. He has not shown his typical control in three starts since returning in a 4-3 victory at Baltimore on April 14. He has surrendered 13 runs on 16 hits in his two most recent starts while walking eight, ballooning his WHIP to 2.25.

Kelly was asked if command of his four-pitch repertoire might be the last thing to come after the injury-forced layoff.

“I think every comeback is different,” he said after walking five in a 13-2 loss at Milwaukee on Tuesday. “I think everybody’s different. The answer for me right now is ‘yes.’ I have to stop putting myself in bad situations.”

Kelly is 3-1 with a 3.25 ERA in eight career starts against the Cubs, the most recent an 8-1 victory in Arizona on March 28, 2025. Michael Busch is 2-for-6 with a homer against him.

–Field Level Media