Buffalo Sabres vs Montreal Canadiens Picks and Predictions May 6th 2026

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Game 1 of the Eastern Conference second round lands in Buffalo on Wednesday night, with puck drop set for 7:00 PM ET at KeyBank Center. The Sabres earned home ice as the No. 1 seed out of the Atlantic, while Montreal arrives after surviving a grinding seven-game series against Tampa Bay. This is a fresh best-of-7, but it does not feel like a mystery matchup. These teams know each other well, split the regular-season series 2-2, and both come in with real belief.

Montreal’s path here was dramatic. The Canadiens beat Tampa Bay 2-1 in Game 7 on Sunday despite managing only nine shots, with Nick Suzuki and Alex Newhook scoring and Jakub Dobes turning away 28 of 29 shots. Buffalo got here a little more comfortably, knocking out Boston in six games with a 4-1 road win in Game 6 behind goals from Alex Tuch, Mattias Samuelsson, Zach Benson, and Josh Norris. That difference in how each team arrived matters to me. Montreal showed resilience, but Buffalo looked fresher and more in control by the end of Round 1.

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Montreal Canadiens vs Buffalo Sabres Odds

These are the betting lines for this preview, and bettors should always monitor updated NHL odds before placing anything. Buffalo is a short home favorite, which feels about right for a top seed opening at home against a team that just emptied the tank in a seven-game series.

TeamMoneylinePuck LineTotal
Montreal Canadiens+108+1.5 (-230)O 5.5 (-123)
Buffalo Sabres-126-1.5 (+190)U 5.5 (+102)

Montreal Canadiens Betting Form

Montreal is not an easy team to price because the Canadiens can look almost overwhelmed territorially and still win the game anyway. That happened in Game 7 against Tampa Bay, and it speaks to how much trust this team now has in Dobes. He was strong throughout the first round, and NHL.com notes he posted a .923 save percentage against the Lightning after a strong finish to the regular season. That gives Montreal a very real underdog path, especially in lower-event games where one hot goalie can flip the board.

I still think there is some danger in leaning too hard into that formula. Playing from your own zone for long stretches is exhausting, and Buffalo has more pace and a little more offensive depth than the version of Tampa Bay Montreal just survived. Patrik Laine remains listed as injured in the official second-round series preview, so the Canadiens are still missing a scorer who could help punish Buffalo on the power play or in transition. Montreal can absolutely hang here, but the margin for error feels thin.

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Buffalo Sabres Betting Form

Buffalo looks like the steadier side coming into this opener. The Sabres won the Atlantic, handled Boston in six, and got excellent work from Alex Lyon after he took over the crease in the first round. NHL.com’s series preview notes Lyon went 3-1 with a 1.14 goals-against average and .955 save percentage after seizing the starting role, and Sabres team coverage said Tuesday that he is set to start Game 1 again. That is a big edge for Buffalo because the crease has stopped looking like a question mark and started looking like a strength.

The injury situation is not perfect, but it is manageable. Sam Carrick returned to practice and is considered day to day, though Sabres team coverage indicated he was not expected to play Wednesday. Noah Ostlund remains out through at least Round 2, and Jiri Kulich and Justin Danforth are still sidelined, but Buffalo has kept rolling anyway. Logan Stanley was back on the third pair at practice, which helps the blue line depth a bit. More importantly, the core is driving play. Tuch and Tage Thompson both had seven points against Boston, and that top-end creation is a major reason Buffalo deserves favorite status at home.

Montreal Canadiens vs Buffalo Sabres Matchup Breakdown

This series opener probably comes down to whether Montreal can keep it in that tight, uncomfortable playoff script it used against Tampa Bay. The Canadiens block shots, play hard around the net, and do not mind ugly hockey. If this becomes another one-goal game in the third period, Montreal is live. The problem is Buffalo is built to create more layered pressure than Tampa Bay managed in some of those games. The Sabres have enough skill up front to stretch coverage and enough confidence right now to keep pushing after the first wave gets turned away.

Goaltending is the swing factor, and it is a really interesting one. Lyon has been exceptional since taking over, but NHL.com’s goalie matchup breakdown also points out that his aggressive depth can leave him vulnerable on fast east-west looks and second-touch chances. Dobes, meanwhile, has been the more conservative, reactive type lately, and that fits playoff hockey pretty well. I think that makes the total tricky. A 5.5 looks low on paper, but both teams can justify it. Buffalo’s offensive ceiling says over, while the goalie form and the playoff style say under.

The other thing I keep circling back to is rest and game state. Buffalo has had a little more time to get ready after closing out Boston in six, while Montreal had to survive a Game 7 on Sunday. That does not always show up in the first ten minutes, but it can show up later in the game, especially if Buffalo is forcing the Canadiens to defend long sequences in their own end. That is one reason I trust Buffalo more on the side than I trust either total angle.

Montreal Canadiens vs Buffalo Sabres Predictions and Best Bets

My lean is Buffalo on the moneyline. It is not a runaway favorite spot, and I would not pretend Montreal is just happy to be here. The Canadiens have already shown they can win ugly, and Dobes gives them a chance every night. But this is still the top seed in the Atlantic, at home, with the better rest profile and the more stable overall team game entering the series. Buffalo also feels a little less dependent on one specific script. It can win a 3-2 game, but it can also turn this into a 4-2 type of night if the forecheck starts to tilt the ice.

As for the total, I get the over case because Buffalo can push pace and Montreal has enough finishing talent around Suzuki, Caufield, and Newhook to cash in on a few mistakes. Still, 5.5 is not a gift in playoff hockey, and both goalies are coming in hot. For me, that is more of a secondary lean than a primary bet. If you want action there, over 5.5 is defensible, but I would rather bet the Sabres than force a total.

Buffalo’s number is short enough that I still think it is playable. The Sabres have the better recent profile, the better rest spot, home ice, and a goaltending situation that looks much more trustworthy than it did a week ago. Montreal can absolutely make this tense, maybe even drag it to the wire, but Buffalo is the side I would back first.

Best Bet: Buffalo Sabres moneyline (-126).

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NHL Picks and Handicappers on ScoresAndStats

If you are building out a playoff card instead of betting just one game, it helps to compare this matchup with the rest of the NHL board and see where the strongest numbers line up. That is especially true in the postseason, where pricing gets tighter and one matchup edge can matter more than broad season-long trends.

ScoresAndStats is useful for that because you can compare daily NHL picks, track different handicapping styles, and see which cappers are finding value on sides, totals, and derivative markets. In the playoffs, that matters. Some bettors want a clean moneyline favorite like Buffalo. Others would rather attack goalie form, game flow, or series-adjustment spots from game to game.

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