Minnesota Twins vs Los Angeles Dodgers Picks and Predictions June 22nd 2026

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The Los Angeles Dodgers visit the Minnesota Twins on Monday night at Target Field, with first pitch set for 7:40 PM ET on SportsNet LA and Twins.TV. Los Angeles comes in at 49-29 and first in the NL West, while Minnesota is 38-41 and third in the AL Central. The Dodgers have dropped two straight, but they still bring one of the best offensive profiles in baseball into this series opener.

Minnesota has won two straight and five of its last six, so this is not a simple fade-the-home-dog spot. The Twins are coming off a 4-2 win over Arizona after also putting up 16 runs one day earlier. That current form matters, especially against a Dodgers starter who has been vulnerable to home runs.

Eric Lauer starts for Los Angeles with a 2-5 record and 5.37 ERA. Minnesota counters with Zebby Matthews, who is 3-4 with a 4.78 ERA. The weather should be warm and mostly cloudy around first pitch, but Target Field should not play like an extreme hitting environment. This handicap is more about two vulnerable starters and whether the Dodgers’ lineup edge is enough to justify the road favorite price on the Monday MLB previews board.

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Los Angeles Dodgers vs Minnesota Twins Odds

These are the current betting lines for Dodgers vs Twins, and bettors should always monitor the latest MLB odds before placing a wager.

TeamMoneylineRun LineTotal
Los Angeles Dodgers-156-1.5O 9.0
Minnesota Twins+132+1.5U 9.0

Los Angeles Dodgers Betting Form

The Dodgers are coming off an ugly 12-1 loss to Baltimore, and that followed a 3-2 loss one day earlier. It is still hard to panic over this lineup. Los Angeles leads or sits near the top of MLB in batting average, on-base percentage, home runs, and run creation, and it has too many impact bats to stay quiet for long. You can follow more of the Los Angeles Dodgers stats and results as they start this road trip.

Lauer’s surface numbers are the concern. A 5.37 ERA is not the profile most bettors want when laying a road favorite price, and the home run risk is real. The more positive angle is that he has pitched better since joining the Dodgers, giving Los Angeles competitive length in each of his first four starts with the club. That matters because this team can win if Lauer simply keeps the game manageable.

The Dodgers’ injury list is still heavy. Will Smith, Teoscar Hernández, Tyler Glasnow, Blake Snell, Edwin Díaz, Blake Treinen, Evan Phillips, Brusdar Graterol, Bobby Miller, and others are either out or dealing with availability concerns. Even so, Shohei Ohtani, Mookie Betts, Freddie Freeman, Max Muncy, Tommy Edman, Andy Pages, Kyle Tucker, and Dalton Rushing give Los Angeles a much deeper offensive group than Minnesota.

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Minnesota Twins

Minnesota Twins Betting Form

The Twins are playing better baseball right now. They beat Arizona 4-2 on Sunday, won 16-8 on Saturday, and have scored at least four runs in five straight games. That is a real offensive pulse, and it comes with enough power to make Lauer uncomfortable. The Minnesota Twins schedule and stats show a team still below .500, but the recent form is stronger than the season record.

Matthews has to be sharper than his ERA suggests. His 4.78 ERA and 1.18 WHIP are not disastrous, but this is one of the tougher lineups he can face. The Dodgers do not just hit for power. They also get on base, extend innings, and force pitchers into high-stress counts. If Matthews is behind early, Minnesota’s bullpen could be working before the sixth.

The Twins can win if their power carries over. Byron Buxton has been the biggest threat with 24 home runs, while Josh Bell, Trevor Larnach, Brooks Lee, Luke Keaschall, Royce Lewis, Alex Jackson, and Victor Caratini give Minnesota enough thump around him. The issue is run prevention. With Pablo López, Bailey Ober, Ryan Jeffers, Cole Sands, David Festa, and others unavailable, the Twins do not have much margin if Matthews struggles.

Los Angeles Dodgers vs Minnesota Twins Matchup Breakdown

The offensive edge belongs to Los Angeles. The Dodgers have the better lineup, more left-right balance, more proven power, and a better on-base foundation. That matters against Matthews, who has not shown enough dominance to make this a comfortable matchup for Minnesota.

The starting pitching comparison is closer than the team reputations suggest. Lauer’s ERA is worse than Matthews’ mark, and he already had a rough outing against Minnesota earlier in the season while pitching for Toronto. The Twins have seen him before, and their current lineup form gives them a path to early runs.

The total is interesting because the matchup points toward offense, but the market has already accounted for it. A number around 9.0 or 9.5 is not cheap. The Dodgers can clear a team total against Matthews, but Minnesota’s ability to contribute against Lauer is what determines whether the full-game Over gets there.

From an MLB betting guide perspective, this is a spot where side and total overlap. If Los Angeles wins, it likely does so by hitting Matthews and forcing Minnesota into middle relief. That makes the Dodgers moneyline playable, but the favorite price is not a bargain with Lauer on the mound.

Los Angeles Dodgers vs Minnesota Twins Predictions and Best Bets

I lean Dodgers moneyline at -156. Los Angeles has the better lineup, better overall pitching staff, better bullpen depth, and more ways to create runs. The two-game losing streak is not enough to move me off the Dodgers when the matchup still favors their bats.

Minnesota is dangerous at +132 because the Twins are swinging well and Lauer has home run risk. If Buxton or Larnach gets to him early, this game can flip. That said, Matthews against this Dodgers lineup is the bigger problem. Minnesota may need five or six runs to win, and that is a lot to ask against the better full-game roster.

The total leans Over 9.0, but it is not my favorite play. Both starters can give up traffic, and both offenses have enough power to make the bullpens matter. The risk is that the Dodgers jump ahead and the Twins go quiet late, or that the market has pushed the total high enough to create a push. My projection lands around Dodgers 6, Twins 4.

If you are comparing this matchup with the rest of today’s MLB picks, Dodgers moneyline is the best fit. It is not a cheap favorite, but the lineup gap is real, and Los Angeles should be able to respond after two poor offensive games.

Best Bet: Dodgers Moneyline -156.

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MLB Picks and Handicappers on ScoresAndStats

MLB betting is about knowing when a favorite is expensive but still justified. Dodgers vs Twins is a good example because Lauer creates some discomfort, but the Dodgers’ lineup and full-game depth still give them the better betting profile.

ScoresAndStats helps bettors compare top sports handicappers, check transparent results on the handicapper leaderboard, and see which experts are finding value across the full baseball board.

For bettors building a Monday card, premium MLB picks can help sort through moneylines, run lines, totals, props, and first five inning markets. Baseball creates plenty of spots where recent form points one way and roster quality points another, and this matchup still leans toward the better offense.

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