Cincinnati Reds vs San Diego Padres Picks and Predictions June 27th 2025

Cincinnati Reds vs San Diego Padres June 27th 2025

The San Diego Padres will visit the Cincinnati Reds at Great American Ball Park on Friday, June 27, 2025. The game is set to start at 7:10 PM under the lights, with a forecast of a very hot day and a light breeze. Fans can catch the action on the SDPA channel.

The Padres, led by manager Mike Schildt, hold a record of 44-36 this season. They are currently 6 games back in the NL West. On the mound for the Padres will be Dylan Cease, who has an ERA of 4.43 and a WHIP of 1.29. The Reds, managed by Terry Francona, have a record of 42-39 and are also 6 games back in their division, the NL Central. Nick Martinez will start for the Reds, bringing an ERA of 4.39 and a WHIP of 1.23.

Padres vs Reds Key Information

• Sport: Baseball
• Teams: San Diego Padres vs. Cincinnati Reds
• Venue: Great American Ball Park in Cincinnati, OH
• Date: Friday, June 27, 2025
• Betting Odds: Padres MoneyLine -141, Reds MoneyLine +120

The Padres Can Win If…

The San Diego Padres recently won a tight 1-0 game against the Washington Nationals. Nick Pivetta led the way with an impressive performance, pitching seven innings with 10 strikeouts and no runs allowed. Luis Arraez contributed with three hits, including the game’s only RBI.

The Padres’ pitching has been strong this season, with a team ERA of 3.62, ranking 9th in the league. Their batting average against is .227, placing them 4th. This solid pitching foundation gives them a good chance to win their upcoming game.

Manny Machado is a key player for the Padres, with a batting average of .298 and 13 home runs. Fernando Tatis Jr. also adds power to the lineup with 15 home runs. With Dylan Cease on the mound, the Padres have a solid chance to secure another win.

The Reds Can Win If…

The Cincinnati Reds are looking to bounce back after a tough 7-1 loss to the New York Yankees. In that game, Elly De La Cruz was a bright spot, going 2-for-4 with a run scored. Despite the loss, the Reds have shown they can compete, with recent wins against the Yankees, including a 5-4 victory on June 24th.

The Reds’ offense ranks 9th in batting average at .247, showing they can hit consistently. They also have 135 doubles, ranking 6th, which helps them get into scoring positions. With Elly De La Cruz leading the team in home runs and RBIs, the Reds have the firepower to score runs.

Nick Martinez will start on the mound for the Reds, with an ERA of 4.39. Martinez aims to improve his record and help the team secure a win. The Reds’ pitching staff has a solid batting average against of .233, ranking 7th, which can limit the Padres’ offense.

The Lean

The Padres are favored to win with a MoneyLine of -141. They have a strong pitching staff with a 3.62 ERA, ranked 9th in the league. The Reds have a higher ERA of 3.85, ranked 13th. Given these stats, the Padres are likely to win. My model projects a score of Padres 5, Reds 4.

The over/under line is set at 9.0. Both teams have shown decent hitting capabilities, with the Padres ranked 8th in batting average and the Reds ranked 9th. The Reds have hit more home runs, ranked 13th compared to the Padres’ 23rd. With both teams capable of scoring, I recommend taking the over. The projected total is 9 runs.

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‘Battle-Tested’ Padres Visit Confident Reds in Series Opener

The San Diego Padres finally got to take a collective exhale. After completing a grueling stretch of 26 games in 27 days, the “battle-tested” San Diego Padres enjoyed a rare day off Thursday. They’ll get back to work on Friday night as they open a three-game series against a host Cincinnati Reds team whose confidence is soaring.

The “Battle-Tested” Padres

Padres manager Mike Shildt could not be prouder of his club. They navigated their brutal schedule and capped it with a 1-0 win over the Nationals on Wednesday, a game where their overworked bullpen stepped up to cover for a suspended closer.

“My admiration and appreciation and love for this team is even higher than it was,” Shildt said. “You talk about being battle tested, the season will do that… That’s what great teams have — guys that just get it done.”

A Playoff Mentality in Cincy

While the Padres are tough, the Reds are confident. Despite a loss in their last game, Cincinnati has won 12 of its last 17 and has started to carry itself differently. The belief in their clubhouse is growing.

“We’re a playoff team,” said Reds infielder Jonathan India. “I really believe that we are a playoff team, and we’ve just got to stay healthy and continuing to play team baseball. We have the talent in this room, too.” The impact of a team’s mid-season change in confidence is a key factor in our expert betting guide.

A Duel of Right-Handers

Friday’s pitching matchup features two right-handers looking to build on recent success. The Padres will start Dylan Cease (3-6, 4.43 ERA), who is coming off a stellar bounce-back performance where he allowed just one run over 6 2/3 innings.

The Reds will counter with Nick Martinez (4-8, 4.40 ERA). After struggling as a starter, Martinez has been lights-out in his last two appearances out of the bullpen, tossing three scoreless innings. He’ll look to carry that success into his start on Friday. This matchup will be a key focus on the scores and odds board.

Stars on a Streak

Both offenses are led by a star player on a hot streak. For the Padres, three-time batting champion Luis Arraez is riding a 12-game hitting streak. For the Reds, dynamic shortstop Elly De La Cruz has a six-game hitting streak of his own. The performance of these stars will be crucial for two MLB teams looking to start a new series with a win. To see who our experts are backing, check out our daily MLB picks.