The New York Yankees and Cleveland Guardians continue their three-game series Tuesday night at Progressive Field. First pitch is scheduled for 6:40 PM ET, with coverage on TBS, Amazon Prime Video, and Cleveland’s local broadcast. New York enters at 39-26 and second in the AL East, while Cleveland is 37-31 and remains first in the AL Central.
The Yankees won Monday’s opener 7-5 in 10 innings after Cody Bellinger delivered a two-run single with the bases loaded. New York has won nine of its last 13 despite missing Aaron Judge, while Cleveland has dropped four of five and went 0-for-11 with runners in scoring position Monday.
Gerrit Cole starts for New York against Slade Cecconi. Cole is making his fourth start since returning from Tommy John surgery, while Cecconi gets another look at a Yankees lineup he held to one run across six innings last Thursday. New York is a moderate road favorite, with the total sitting at 8.5 runs.
New York Yankees vs Cleveland Guardians Odds
These are the current betting lines for New York vs Cleveland. Bettors should monitor the latest MLB odds because prices may move with the weather forecast and both bullpens coming off a 10-inning opener.
| Team | Moneyline | Run Line | Total |
|---|---|---|---|
| New York Yankees | -134 | -1.5 (+162) | O 8.5 (-107) |
| Cleveland Guardians | +113 | +1.5 (-200) | U 8.5 (-112) |
New York Yankees Betting Form
New York is finding ways to score without Judge, but the lineup is clearly less intimidating without its most dangerous hitter. Paul Goldschmidt homered and drove in three runs Monday, Ryan McMahon added a solo shot, and Bellinger produced the decisive hit in extra innings. Ben Rice remains the central threat with 18 home runs, while Bellinger, Jazz Chisholm Jr., Trent Grisham, Goldschmidt, and McMahon must continue sharing the missing production. Bettors tracking how the lineup adjusts can compare Tuesday’s matchup with the broader collection of Yankees betting previews and analysis.
The injury list remains significant. Judge is expected to miss an extended period with a stress fracture in his right rib, Austin Wells is out with cervical headaches, Giancarlo Stanton is recovering from a calf strain, and Jasson Domínguez is still completing a rehabilitation assignment for his shoulder. Wells’ MRI did not reveal a major problem, but his return date remains unclear.
Cole enters at 1-1 with a 2.00 ERA, 0.89 WHIP, 14 strikeouts, and four walks through 18 innings. His first two starts produced 12.2 scoreless innings, but Cleveland reached him for four runs and three homers across 5.1 innings last Wednesday. Cole recorded only two strikeouts in that outing after reaching double digits against Kansas City in his previous start.
That recent meeting makes the matchup more complicated than Cole’s ERA suggests. He reached approximately 80 pitches against Cleveland, so a normal six-inning workload is realistic if he works efficiently. The Yankees need that length after using seven relievers Monday. David Bednar recorded five outs, while Ryan Yarbrough, Tim Hill, Paul Blackburn, and several other arms were needed after Will Warren exited in the fifth.
Cleveland Guardians Betting Form
Cleveland generated 11 baserunners and scored five runs Monday, but its inability to produce a hit with runners in scoring position decided the game. Angel Martínez hit a two-run homer, while Steven Kwan, Patrick Bailey, Brayan Rocchio, José Ramírez, and Kyle Manzardo helped create repeated traffic. The Guardians have enough contact and patience to make Cole work, even though they lack New York’s overall home-run production. Bettors comparing Cleveland’s underdog price with the full slate can review the daily MLB picks and predictions.
The Guardians are averaging a little more than four runs per game while ranking near the bottom of MLB in batting average and home runs. Ramírez remains the hitter New York must avoid giving free opportunities, but Rocchio, Kwan, Travis Bazzana, Manzardo, and Martínez can extend innings around him. Cleveland’s lineup is more dangerous when it forces pitchers into the stretch rather than depending on isolated power.
Cecconi is 3-5 with a 4.92 ERA, 1.43 WHIP, 54 strikeouts, and 21 walks over 67.2 innings. He has allowed 76 hits and nine homers, which makes the full-season profile difficult to trust against a power lineup. Still, his most recent start came against these Yankees, and he held them to one run on four hits over six innings while walking one and striking out four.
Cecconi’s challenge is repeating that performance before New York adjusts. He located well enough to avoid the middle of the plate last week, but the Yankees now have a fresh scouting look at how he attacked Rice, Bellinger, Chisholm, and Goldschmidt. His lower strikeout rate also means Cleveland’s defense must convert a high number of balls in play.
Cleveland’s bullpen was also extended Monday. Hunter Gaddis allowed the tying run in the eighth, and Shawn Armstrong handled the tenth before surrendering Bellinger’s go-ahead single. Cade Smith remains Cleveland’s primary closing option, but the Guardians do not enter Tuesday with the same late-inning freshness they would have after a normal nine-inning game.
New York Yankees vs Cleveland Guardians Matchup Breakdown
The starting-pitcher edge belongs to New York, though Cole’s previous outing prevents this from being an automatic play. Cleveland hit three home runs against him less than a week ago, and the Guardians generally do a good job extending at-bats. Cole must avoid becoming too predictable with his fastball when behind in counts. His first two starts showed that the command and swing-and-miss ability are still present, but his workload remains more controlled than it would be later in the season.
Cecconi has the recent head-to-head edge, but his full-season numbers point toward regression from last Thursday’s outing. A 1.43 WHIP against a Yankees lineup that leads MLB in home-run rate creates obvious danger. New York is missing Judge, Stanton, and Wells, yet Rice, Bellinger, Chisholm, Goldschmidt, McMahon, and Grisham still provide more power than Cleveland can match from top to bottom.
The bullpen situation makes the first five innings worth considering. New York used seven relievers Monday and asked Bednar to record five outs. Cleveland also needed its primary setup options during the extra-inning loss. The Yankees have the stronger starter and offensive ceiling, but their full-game advantage becomes smaller if Cole exits after five innings. Understanding that starter-to-bullpen transition is an important part of a sound MLB betting guide.
The current weather forecast is not as severe around first pitch as the earlier outlook suggested. Thunderstorms are possible during the late afternoon, but conditions are expected to be cloudy and around 79 degrees at 6:40 PM, with temperatures slowly dropping through the evening. A delay remains possible if the earlier system lingers, though steady moderate rain is not the current base forecast during most of the game window.
Warm conditions can help the ball carry at Progressive Field, which adds some risk to an Under position. The matchup still leans toward moderate scoring because Cole can miss bats, Cecconi handled this lineup five days ago, and both offenses are missing important hitters. The tired bullpens are the main reason the total is more difficult than the starting matchup alone suggests.
New York Yankees vs Cleveland Guardians Predictions and Best Bets
I lean toward the Yankees on the moneyline. My projection makes New York approximately a -148 favorite, leaving value at the current -134 price. Cole is the better starter, the Yankees have the deeper power profile, and Cleveland has lost four of five despite remaining at the top of its division.
Cole’s recent performance against Cleveland creates real risk. The Guardians saw his fastball well and punished three mistakes for home runs. Still, one uneven start after Tommy John surgery does not erase the 12.2 scoreless innings he produced in his first two appearances. I expect a better mix of fastballs and breaking pitches in the rematch.
The total leans slightly Under 8.5. Cecconi’s recent six-inning performance suggests he can keep New York competitive early, while Cleveland has scored four or fewer runs in most of its recent games. The warm weather and bullpen fatigue prevent me from making the Under the primary wager. A 4-3 game can quickly become 6-4 once the starters leave.
New York’s first-five moneyline is another playable angle if offered around -120, but the straight moneyline provides more flexibility if Cecconi repeats his early success. The Yankees still have enough late power to win against Cleveland’s middle relief. Bettors comparing this position with other premium MLB picks should keep New York playable through approximately -145.
My projected score is Yankees 5, Guardians 3.
Best Bet: Yankees Moneyline -134.
MLB Picks and Handicappers on ScoresAndStats
A full MLB card creates betting opportunities across moneylines, run lines, totals, team totals, first-five markets, and pitcher props. ScoresAndStats allows bettors to compare different approaches through its top sports handicappers page rather than depending on one opinion for every matchup.
Long-term records, recent performance, and transparent profit can also be reviewed through the handicapper leaderboard. That context matters in rematches like Cole against Cleveland, where one recent result must be balanced against season-long pitching quality, lineup strength, bullpen availability, and the current market price.


