The Chicago Cubs visit the Pittsburgh Pirates on Monday afternoon at PNC Park, with first pitch set for 1:35 PM ET. Chicago is trying to stop an eight-game losing streak, and the timing is not ideal. The Cubs just finished a miserable homestand and now begin a seven-game road trip with the pressure clearly building.
Pittsburgh comes in with a little more confidence after salvaging its weekend series in Toronto with a 4-1 win. The Pirates are not exactly rolling, but they have been more competitive inside the division than the market sometimes gives them credit for. That matters in a short-priced game like this, where the Cubs are still favored despite their current slide.
Ben Brown starts for Chicago, while Carmen Mlodzinski gets the ball for Pittsburgh. Light rain is in the forecast at PNC Park, and that could make conditions a little awkward, though it does not completely flip the handicap. This matchup belongs on the broader MLB previews board because Chicago has the better on-base profile, but Pittsburgh has the better recent mood and a starter with strong history against the Cubs.
Chicago Cubs vs Pittsburgh Pirates Odds
These are the current betting lines for Chicago vs Pittsburgh, and bettors should always monitor the latest MLB odds before locking in a number.
| Team | Moneyline | Run Line | Total |
|---|---|---|---|
| Chicago Cubs | -117 | -1.5 (+144) | O 8.0 (-107) |
| Pittsburgh Pirates | -101 | +1.5 (-173) | U 8.0 (-113) |
Chicago Cubs Betting Form
Chicago’s form is hard to ignore. The Cubs have dropped eight straight, and Sunday’s 8-5 loss to Houston was another game where they showed pieces of offense but still could not finish the job. Michael Busch homered, Pedro Ramirez added an RBI double, and the Cubs scored five runs after managing only seven total over their previous five games. So there was at least a little spark.
The bigger-picture offensive profile is still strong. The Cubs rank near the top of the league in on-base percentage and lead MLB in walks, which gives them a path against Mlodzinski if they stay patient. That is the part I like for Chicago. They do not need to chase hits early. They can work counts, force Pittsburgh into leverage spots, and try to make this a bullpen game.
Brown gives the Cubs a good chance to stabilize the first half. His 2.09 ERA and 40 strikeouts show the raw run-prevention profile, and he has been useful since moving into the rotation. The issue is workload and role adjustment. This is still a pitcher trying to prove he can hold a rotation spot, not a fully settled starter. If he gives Chicago five clean innings, the Cubs can absolutely win. If the bullpen gets exposed too early, the losing streak pressure gets heavier.
Pittsburgh Pirates Betting Form
Pittsburgh needed Sunday’s win in Toronto. The Pirates had dropped two straight in that series before beating the Blue Jays 4-1 behind a strong Mitch Keller outing and home runs from Esmerlyn Valdez, Spencer Horwitz, and Oneil Cruz. That win does not fix everything, but it gives the Pirates a better entry point into this home series.
The Pirates’ offensive profile is better than the casual record might suggest. They rank well in batting average and on-base percentage, and they have enough left-handed power to make Brown work. Oneil Cruz is always the obvious swing piece, but Pittsburgh has been getting contributions from younger bats too. Konnor Griffin, Nick Gonzales, and Horwitz have helped give the lineup a little more depth.
Mlodzinski is not overpowering, but he has handled the Cubs well. He threw 5 1/3 scoreless innings against them in April and has a strong career ERA in this matchup. His last start was also encouraging, with five scoreless innings against St. Louis. The strikeout ceiling is not huge, but if he keeps the ball on the ground and avoids walks, Pittsburgh has a real chance to drag this into a tight home game.
Chicago Cubs vs Pittsburgh Pirates Matchup Breakdown
The starting-pitcher matchup is tighter than the season ERAs suggest. Brown has the better overall number and better strikeout profile, but Mlodzinski has the better matchup history against Chicago. That matters because the Cubs are not just losing games. They are pressing, and pressure can make even disciplined lineups expand the zone when early chances do not cash.
Chicago’s best path is traffic. The Cubs lead the league in walks, and that is how they can beat Mlodzinski without needing a big power game. If they get runners on ahead of Busch, Pete Crow-Armstrong, or the middle of the order, Pittsburgh’s bullpen will have to work in uncomfortable spots.
Pittsburgh’s best path is contact and timing. The Pirates do not need to dominate Brown. They just need to make him throw enough pitches, get into the Cubs bullpen, and keep the game close. Chicago’s rotation depth has also taken hits, and when a team is on an eight-game skid, every defensive misplay or bullpen walk feels bigger than it should.
From an MLB betting guide perspective, this is a spot where form and price matter more than name value. Chicago is favored because Brown is the better current starter and the Cubs still have a strong offensive process. But Pittsburgh is not a bad underdog at essentially even money, especially with Mlodzinski’s recent form.
Chicago Cubs vs Pittsburgh Pirates Predictions and Best Bets
I lean Cubs to win, but it is not comfortable. Brown gives Chicago the better starter projection, and the Cubs’ plate discipline should create scoring chances. At some point, this lineup is too good at reaching base to stay completely stuck. The question is whether that correction starts here or whether the losing streak keeps feeding itself.
Pittsburgh is very live. Mlodzinski has handled Chicago before, the Pirates just got a good road win, and PNC Park in light rain can create a lower-tempo game where the underdog stays close. The Pirates +1.5 is logical, but the juice is too expensive for me to make it the best bet.
The total is the better angle. I know the model projection lands right on eight, but both offenses have enough on-base ability to push this over if either starter exits after five. The Cubs walk rate should create chances, and Pittsburgh’s contact profile can do damage against Chicago’s middle relief. It is not a pure slugfest handicap. It is more about traffic, bullpen exposure, and one crooked inning.
For bettors comparing this matchup with the full daily MLB picks board, the Cubs moneyline is playable, but the Over gives a slightly cleaner path if both teams generate baserunners. I would rather avoid guessing which struggling team handles late innings better.
Best Bet: Over 8.0 (-107).
MLB Picks and Handicappers on ScoresAndStats
MLB betting gets uncomfortable in spots like this because the obvious narrative can push bettors too far. The Cubs are due to win eventually, but that does not automatically mean the price is right. Pittsburgh has a starter who has matched up well with them, and divisional games can tighten fast.
The handicapper leaderboard helps bettors compare long-term records and profit instead of reacting to one hot streak or one ugly losing run. That matters in baseball because the daily board is deep, and good handicappers need to prove they can win across sides, totals, run lines, team totals, and first 5 innings markets.
Bettors looking for more daily baseball opinions can also compare premium MLB picks before first pitch. In a game like Cubs vs Pirates, the difference between taking a short road favorite and attacking the total is meaningful. The market matters as much as the matchup.


