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San Francisco is the favorite to win the NFC West at +144, and it is tied with Seattle at 2-0 after two weeks of the 2026 season. The Rams and Cardinals are both 1-1.
Both leaders have a division win already. The 49ers beat the Rams 27-7 at the Melbourne Cricket Ground in Week 1, and Seattle won 31-7 at Arizona on September 20.
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NFC West standings after Week 2
| Team | W-L | Points for | Points against | Home | Road | Streak |
|---|---|---|---|---|---|---|
| Seattle Seahawks | 2-0 | 44 | 17 | 1-0 | 1-0 | W2 |
| San Francisco 49ers | 2-0 | 62 | 20 | 1-0 | 1-0 | W2 |
| Los Angeles Rams | 1-1 | 35 | 33 | 1-1 | 0-0 | W1 |
| Arizona Cardinals | 1-1 | 33 | 45 | 0-1 | 1-0 | L1 |
Seattle has allowed 17 points in two games and San Francisco 20. The 49ers have the widest margin in the division, 42 points, after beating Miami 35-13 at Levi’s Stadium in Week 2.
How each team got here
Seattle won Super Bowl LX, 29-13 over New England, and opened this season against the same team. The Seahawks beat the Patriots 13-10 at Lumen Field on Wednesday, September 9, then won in Arizona.
ESPN lists the Rams as the home team for the Melbourne game, which is why their home record is 1-1. They beat the Giants 28-6 at SoFi Stadium on Monday night, September 21. Arizona won 26-14 at the Chargers in Week 1 before the loss to Seattle.
Last season Seattle went 14-3, San Francisco and the Rams 12-5, and Arizona 3-14. The Cardinals are the one NFC West team with a new head coach: Jonathan Gannon was fired on January 5 and Mike LaFleur, the Rams’ offensive coordinator, was hired on February 1. Mike Macdonald, Kyle Shanahan and Sean McVay are back in Seattle, San Francisco and Los Angeles. The full list of changes is on our NFL coaches fired page.
Each team page carries its schedule and next game: San Francisco 49ers, Seattle Seahawks, Los Angeles Rams and Arizona Cardinals.
Week 3 for the NFC West
- Seahawks at Commanders, Sunday, September 27, 1:00 pm ET: Seahawks -7, total 40
- Cardinals at 49ers, Sunday, September 27, 4:05 pm ET: 49ers -8.5, total 48
- Rams at Broncos, Sunday, September 27, 8:20 pm ET: Rams -2.5, total 44.5
Lines are the median of 11 sportsbooks as of September 24, 00:10 UTC. Cardinals at 49ers is the division’s third game inside the NFC West, and San Francisco is an 8.5-point favorite. The Rams play the Sunday night game in Denver, and the Sunday Night Football odds page has the full line.
NFC West division odds
| Team | Price to win the division | Chance implied by the price |
|---|---|---|
| San Francisco 49ers | +144 | 41.0% |
| Seattle Seahawks | +164 | 37.9% |
| Los Angeles Rams | +240 | 29.4% |
| Arizona Cardinals | +10000 | 1.0% |
These are DraftKings prices for the 2026 season, as ESPN listed them on September 24. At +144, a $100 bet returns $144 profit, and the price says San Francisco wins the division 41.0% of the time. The four chances add up to 109.3%, and the extra 9.3 points is the book’s margin.
Arizona is 1-1 and priced at +10000, a 1.0% chance. A futures bet is worth making only when you rate a team’s chance higher than the price does, and each team has 15 games left.
The week’s game-by-game predictions sit on our NFL predictions hub.
Picks from the site’s own handicappers are on the handicappers page.
