New York Yankees vs Cleveland Guardians Picks and Predictions June 4th 2025

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The Cleveland Guardians will take on the New York Yankees at Yankee Stadium on Wednesday, June 4, 2025. The game is set to begin at 7:05 PM and will be broadcast on AMZP. The weather forecast for the game is currently unavailable.

The Guardians, managed by Stephen Vogt, have a season record of 32-27. They are 6 games back in the AL Central. The Yankees, led by Aaron Boone, hold a 37-22 record. They have been strong at home with a 19-9 record. Starting for the Guardians is Luis L. Ortiz, while Clarke Schmidt will pitch for the Yankees.

Guardians vs Yankees Key Information

  • Sport: Baseball
  • Teams: Cleveland Guardians vs. New York Yankees
  • Venue: Yankee Stadium in New York, NY
  • Date: Wednesday, June 4, 2025
  • Betting Odds: Yankees MoneyLine -185, Guardians MoneyLine +156

The Guardians Can Win If…

The Cleveland Guardians recently played against the New York Yankees and lost 3-2. Tanner Bibee pitched well, going 6 1/3 innings with six strikeouts. José Ramírez stood out with two hits in four at-bats, scoring one run.

Despite the loss, the Guardians have strong stats that suggest they can win. They rank 14th in home runs with 61 and are 8th in strikeouts with 470. Their pitching staff has given up the 10th fewest home runs, showing they can limit the long ball.

José Ramírez is a key player for the Guardians with a .330 batting average and 11 home runs. He ranks 10th in the league for home runs, showing his power. With Luis L. Ortiz on the mound, who has a 4.40 ERA, the Guardians have a chance to control the game.

The Yankees Can Win If…

The New York Yankees are coming off a 3-2 win against the Cleveland Guardians. Carlos Rodón pitched seven innings, allowing just one run and striking out eight. Jazz Chisholm Jr. and Anthony Volpe each hit home runs, providing the necessary offense to secure the win.

Offensively, the Yankees rank second in slugging percentage and home runs this season. Their ability to hit for power can turn any game in their favor. With Aaron Judge leading the team with a .387 average and 21 home runs, the Yankees have a strong lineup capable of producing runs.

On the mound, Clarke Schmidt will start for the Yankees with a 3.95 ERA. The Yankees’ pitching staff holds the best batting average against in the league at .216. This shows their effectiveness in limiting opposing hitters, giving them an edge in this game.

The Lean

The Yankees are the favorites with a moneyline of -185. Their strong hitting stats, including a .258 batting average and 97 home runs, give them an edge. The Guardians’ batting average is lower at .234. My model projects the Yankees to win with a score of 5-3.

The over/under line is set at 9.0. The Yankees have a solid pitching staff with a 3.58 ERA, ranking 8th. The Guardians’ ERA is higher at 4.05. My model predicts a total score of 8 runs. I recommend taking the under for this game.

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Yankees and Guardians Face Off in Crucial Series Showdown

Jazz Chisholm Jr. wasted no time making his mark.

After nearly a month on the injured list, Chisholm reintroduced himself to Yankees fans in the best way possible—by delivering the game-winning homer in a tight 3-2 win over the Cleveland Guardians. The 26-year-old’s return wasn’t just solid; it was impactful.

The crowd’s ovation before his first at-bat said it all. He answered with a single in the fifth, scored the game’s first run, and launched a decisive home run in the seventh. This wasn’t just a comeback—it was a statement.

Manager Aaron Boone was thrilled: “You miss a month and come back swinging like that? That’s exactly the kind of spark this team needed.”

Chisholm’s bat wasn’t the only highlight. Playing third base for the first time this season, he held his own defensively and showcased the versatility the New York Yankees were counting on.

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Yankees Are Dominating One-Run Games and Homestands

The Yankees are on fire at home. With Tuesday’s win, they’ve won five straight at Yankee Stadium and are now 18-6 over their last 24 games overall. They’re not just winning—they’re grinding out close games with poise and precision.

Clutch pitching, timely hitting, and elite bullpen performances have helped the Yankees go 8-3 in their last 11 one-run games. This resilience is turning close contests into consistent wins.

Wednesday offers a chance to lock up another series—what would be their eighth win in nine tries. They’ve been one of the league’s most consistent teams at both ends of the ball, and that consistency is translating into meaningful momentum in the standings.

Pitching for the Yankees will be Clarke Schmidt (2-2, 3.95 ERA). He’s thrown six innings in four of his past five starts, including a brilliant performance against the Angels in which he allowed just four hits over six scoreless frames. While he’s had trouble in the past against Cleveland, he’s showing signs of growth and reliability.

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Guardians Struggle to Capitalize Despite Bright Spots

Cleveland didn’t go down without a fight in Game 1, and they’ll be back swinging on Wednesday. But recent form has been shaky—they’ve now lost five of their last eight.

Jose Ramirez continues to be the heartbeat of the Guardians’ offense, extending his on-base streak to 29 games with a pair of singles. Veteran Carlos Santana also stayed hot, stretching his hitting streak to 12 games with a ninth-inning double.

Yet, the Guardians’ chances were undone by one misstep. After David Fry tied the game in the seventh, Gabriel Arias tried to stretch a single into a double and got gunned down. It was a gamble that didn’t pay off.

Cleveland skipper Stephen Vogt defended the aggressive play: “We want our guys to put pressure on defenses. It didn’t work out this time, but we’ll keep attacking.”

On the mound, Luis L. Ortiz (2-6, 4.40 ERA) will try to snap his personal seven-game winless skid. His ERA over that stretch is a respectable 3.79, but lack of run support and tough matchups have hurt his results. Against the Yankees, Ortiz is 0-2 in three starts with a rough 5.79 ERA.

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Jose Ramirez

Key Matchups and What to Watch For

The Yankees’ offense is getting healthy and dangerous again. With Chisholm back and Bryce Harper-style leadership emerging from multiple corners of the dugout, there’s a noticeable shift in the clubhouse tone—confident, composed, and hungry.

DJ LeMahieu’s bat is heating up at just the right time. Gleyber Torres and Anthony Volpe are stringing together quality at-bats. And behind the plate, the Yankees’ catching tandem continues to anchor the defense and handle the pitching staff with precision.

For Cleveland, they’ll need Ramirez and Santana to set the tone early. Fry and Barger have shown flashes, and if they can get timely contributions from their supporting cast, they’ll be right in the thick of it. Ortiz must limit walks—his five-walk outing against New York earlier this year cost them dearly.

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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