New York Yankees vs Boston Red Sox Picks and Predictions August 21st 2025

New York Yankees vs Boston Red Sox Baseball Thu, Aug 21, 18:15 pm.
New York Yankees
ML: -150
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Boston Red Sox
ML: 120
Last Updated on

The Boston Red Sox will visit the New York Yankees at Yankee Stadium. The game is set for Thursday, August 21, 2025, at 7:15 PM. Fans can catch the action on FOX.

The Red Sox hold a record of 68-59 and are ranked third in the AL East. They have lost their last three games. On the other side, the Yankees have a record of 69-57 and are second in the division. They are on a five-game winning streak.

Red Sox vs Yankees Key Information

  • Sport: Baseball
  • Teams: Boston Red Sox vs. New York Yankees
  • Venue: Yankee Stadium, New York, NY
  • Date: Thursday, August 21, 2025
  • Betting Odds: Red Sox Moneyline +118, Yankees Moneyline -141

The Red Sox Can Win If…

The Boston Red Sox are looking to bounce back after a close 4-3 loss to the Baltimore Orioles. In that game, Nathaniel Lowe hit a home run and drove in two runs, showing his power at the plate. Romy Gonzalez and Connor Wong each contributed with two hits, highlighting the depth in Boston’s lineup.

Boston’s hitting stats show they can win games with strong offensive performances. They rank first in doubles with 257, which can lead to more scoring opportunities. With a team batting average of .252, they are consistent at getting on base and creating chances to score.

The Red Sox pitching staff also provides a solid foundation for winning. Their team ERA of 3.75 ranks sixth, showing they can limit opponents’ scoring. Lucas Giolito, with an ERA of 3.63, will start and aims to keep the Yankees’ hitters in check.

The Yankees Can Win If…

The New York Yankees are coming off a 6-4 win against the Tampa Bay Rays. Trent Grisham and Austin Wells each hit two home runs, adding to the team’s power display. Cam Schlittler was dominant on the mound, allowing just one hit over 6 2/3 innings.

The Yankees lead the league in slugging percentage and home runs. They have hit 209 home runs this season, which ranks them first. Their on-base percentage is also strong, standing at second in the league.

Aaron Judge is a key player with a .330 batting average and 40 home runs. Cody Bellinger and Giancarlo Stanton add depth with their consistent performances. With a lineup full of power hitters, the Yankees have the potential to score big against any team.

The Lean

The Yankees are favored on the moneyline at -141. The Red Sox’s moneyline is +118. With the Yankees having a stronger batting lineup, ranked first in slugging percentage and home runs, the recommendation is to pick the Yankees to win. The model projects the Yankees to win with a score of 5-4.

The total for the game is set at 8.5 runs. Both teams have strong offenses, with the Yankees leading in several hitting categories. The model projects a total score of 9 runs. The recommendation is to take the over at 8.5 (-103).

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Yankees, Red Sox Open Crucial 4-Game AL East Series

Rivalries don’t come bigger than this — and the stakes haven’t been higher all season.

The New York Yankees and Boston Red Sox will meet for the final regular-season series between the clubs starting Thursday night at Yankee Stadium. Both teams are locked in a fierce race for a playoff spot, with the Yankees currently clinging to a 1.5-game lead over Boston for the top AL wild-card position.

This four-game series has massive postseason implications. With both clubs trailing the Toronto Blue Jays in the American League East, these head-to-head contests could be season-defining.

Recent Trends

New York is red hot, having won five straight and nine of its last 12 to climb back into the postseason picture. Wednesday’s 6-4, 10-inning win over the Tampa Bay Rays completed a perfect five-game road trip and marked their fourth separate five-game win streak this year.

Boston, on the other hand, has lost four of five and is struggling with runners in scoring position (3-for-28 over its last three games).

“Obviously we’re kind of neck-and-neck with them,” Yankees manager Aaron Boone said. “This one, with your rival when you’re fighting for a lot, at this point in the season, I’m sure will have a big feel to it.”

AL East Standings

TeamWLGB
Blue Jays7549
Yankees71534.0
Red Sox69556.0

Projected Starting Pitchers – Thursday

TeamPitcherRecordERARecent Form
YankeesLuis Gil1-15.141.00 ERA in last start
Red SoxLucas Giolito8-23.632.84 ERA in August

Gil is rounding into form after returning from injury, giving up just one run over 5 1/3 innings in his last start. Meanwhile, Giolito has been steady for Boston in August, allowing one run across 6 1/3 frames in his last outing.

Key Performers to Watch

  • Giancarlo Stanton: Coming off a pinch-hit, two-run homer in extra innings on Wednesday.
  • Austin Wells & Trent Grisham: Both hit two homers in the final game vs. the Rays.
  • Red Sox Offense: 0-for-13 with RISP and 13 runners stranded in Tuesday’s loss.

What’s at Stake?

Both teams are jockeying not just for wild-card position but to stay within striking distance of the Blue Jays in the division. With Seattle and other contenders in the mix, every game counts.

For more expert insights and analysis, check the MLB Picks and dive into the MLB Expert Betting Guide for sharp predictions throughout the series.