Baltimore Orioles vs New York Yankees Picks and Predictions September 20th 2025

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Yankees vs Orioles Picks and Predictions — September 20, 2025

The New York Yankees continue their late-season push when they face the Baltimore Orioles on Saturday night at Camden Yards. New York (86-68) sits three games behind division-leading Toronto with just eight left to play. Baltimore (73-81), eliminated from postseason contention, has won four of its last five and will look to play spoiler. The Orioles claimed Friday’s opener 4-2 behind Trevor Rogers’ six shutout innings and clutch defense from rookie Dylan Beavers.

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Opening odds:

  • Moneyline: Yankees −198, Orioles +166
  • Runline: Yankees −1.5 (−120), Orioles +1.5 (−101)
  • Total (Over/Under): 9.0 runs

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Yankees Can Win If…

  • Carlos Rodón settles in. The lefty (16-9, 3.11 ERA) has been steady all season but is looking to snap a two-game losing streak. He limited Baltimore to just two hits in six innings back in April.
  • The bats wake up early. The Yankees lead MLB in home runs (259) and slugging percentage (.454), but managed only four hits Friday.
  • The stars carry the load. Aaron Judge and Cody Bellinger headline a lineup that has been one of the most dangerous in baseball down the stretch.

“We’re working to shake hands (after victories) and put ourselves in the best position heading down the stretch,” manager Aaron Boone said.

Orioles Can Win If…

  • Tomoyuki Sugano keeps the Yankees off balance. The rookie right-hander (10-8, 4.39 ERA) hasn’t won since August 14, but he pitched well in a no-decision against Toronto last weekend.
  • Their lineup provides timely power. Baltimore ranks 10th in home runs (181), with Ryan Mountcastle and Gunnar Henderson capable of game-changing swings.
  • Defense continues to shine. Beavers’ highlight-reel plays in left field helped preserve Friday’s win and could be key again against a power-heavy Yankees lineup.

“That team right there … they’ve been one of the best teams in baseball here recently,” interim manager Tony Mansolino said.


Before locking in your bets, review the trends. Get a clearer picture with the latest MLB outcomes

Key MLB Betting Trends

CategoryNew York YankeesBaltimore Orioles
Record86-68 (2nd AL East)73-81 (5th AL East)
Last 10 Games6-4 (lost last game)6-4 (won 4 of last 5)
Runs Per Game5.3 (Top 3 MLB)4.3
ERA / Opp Runs3.95 ERA (9th MLB)4.72 ERA (24th MLB)
Home/Away Record40-36 (Away)39-37 (Home)
Hitting EdgeMLB-best 259 HR181 HR (10th MLB)

The Lean

Pick: Yankees Moneyline (−198)
Projected Final Score: Yankees 6, Orioles 4
Total Lean: Over 9.0

Reasoning: The Yankees’ offensive ceiling remains too high for Baltimore’s inconsistent staff, even with Sugano’s recent form. Rodón has handled the Orioles before and should deliver enough quality innings. Baltimore’s power can keep it competitive, but New York’s need for a bounce-back win tips the balance.

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Best Bet Box

Best Bet CategorySelection
Best BetYankees Moneyline (−198)
Confidence Rating★★★★☆
Projected Final ScoreYankees 6, Orioles 4
Total LeanOver 9.0