New York Yankees vs Baltimore Orioles Picks and Predictions September 28th 2025

New York Yankees vs Baltimore Orioles September 28th 2025

The Baltimore Orioles will take on the New York Yankees at Yankee Stadium. The Orioles have a record of 75-86 and are ranked fifth in the AL East. They are on a two-game losing streak, with a 4-6 record in their last ten games.

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The Yankees hold a strong record of 93-68, sitting at the top of the AL East. They are on a seven-game winning streak and have gone 9-1 in their last ten games. The game will start at 3:05 PM on Sunday, September 28, 2025, and will be aired on MASN.

Orioles vs Yankees Key Information

• Sport: Baseball
• Teams: Baltimore Orioles vs. New York Yankees
• Venue: Yankee Stadium in New York, NY
• Date: Sunday, September 28, 2025
• Betting Odds: Orioles Moneyline +157, Yankees Moneyline -191, Orioles Runline +1.5 (-127), Yankees Runline -1.5 (+105), Total Over 8.5 (-121), Total Under 8.5 (-101)

Orioles vs Yankees MLB Betting Preview

The New York Yankees (93-68) close their season against the Baltimore Orioles (75-86) with the AL East crown still hanging in the balance. For full season stats, check the Yankees team page and Orioles team page.

New York enters riding an eight-game win streak, while Baltimore continues to struggle at the plate. The Yankees and Blue Jays remain tied atop the division, with Toronto holding the tiebreaker.

The Orioles Can Win If…

Kyle Bradish pitches like an ace. Since returning from Tommy John surgery, Bradish has allowed two runs or fewer in all five starts, holding a 2.25 ERA and a 1.00 WHIP. Against a homer-heavy Yankees lineup, keeping runners off base will be critical.

Offensively, Baltimore must get Gunnar Henderson and Jackson Holliday going. The Orioles rank 12th in home runs with 189, but scoring droughts have cost them all September. If the middle of the lineup provides power, Baltimore has a chance to play spoiler.

The Yankees Can Win If…

Luis Gil delivers a quality start. Gil (4-1, 3.29 ERA) has been sharp in four career outings against Baltimore, posting a 3.66 ERA. If he can control his walks, the bullpen and bats can carry the rest.

New York leads MLB in home runs (272), slugging percentage (.455), and on-base percentage (.332). Aaron Judge (.331 AVG, 9 HR in his last 16 games) and Giancarlo Stanton are locked in at the plate. One or two big swings could be enough against Baltimore’s slumping offense.

Matchup Breakdown

• Orioles: Bradish is the X-factor, but Baltimore has been held to three hits or fewer 13 times since Sept. 1. Their lineup has struggled to generate runs consistently.
• Yankees: Their lineup is the most dangerous in baseball. Judge and Stanton both homered Saturday, and Ryan McMahon continues to provide key production.

Find live moneyline and total updates on the MLB odds page.

Best Bets and Prediction

The Yankees are favored at -191, with the Orioles listed at +157. The total is set at 8.5 runs.

• Projected Score: Yankees 5, Orioles 3
• Best Bet: Yankees moneyline -191
• Lean: Under 8.5 (-101) — New York’s pitching plus Baltimore’s struggles at the plate point toward fewer runs.

For more insights, check the MLB picks section and sharpen your postseason edge with the expert MLB betting guide.