Colorado Avalanche vs Buffalo Sabres Picks and Predictions November 13th 2025

Colorado Avalanche vs Buffalo Sabres Week 11 Betting Preview

The Colorado Avalanche host the Buffalo Sabres on Thursday at Ball Arena. Puck-drop is set for 9:00 PM on ESPN+. Colorado enters 11-1-5 and sits atop the NHL. Buffalo is 5-7-4 and still searching for its first road win.

Nathan MacKinnon drives this matchup. He owns a 10-game point streak and leads the league with 32 points. Cale Makar and Martin Necas have pushed Colorado’s pace as well. Buffalo dropped its fourth straight on Wednesday and has struggled to generate consistent offense without key forwards.

If you want a broader slate view, check today’s NHL odds page

Line Movement and Odds

Colorado opened as a heavy favourite. Current market has the Avalanche around -312 on the moneyline with Buffalo at +248. Total sits at 6.5. Openers leaned under and early sharp action backed that direction. Public money leans hard toward Colorado, which is no surprise given the Sabres’ 0-4-2 road mark.

Matchup Breakdown

Avalanche outlook:
Colorado leads the league in goals and assists, driven by MacKinnon’s surge. Even without Valeri Nichushkin, their depth keeps pressure high. Colorado’s puck-possession edge and shot volume tilt this matchup toward long stretches of zone time. For more on how Colorado profiles, check their team page inside the NHL previews section

Sabres outlook:
Buffalo’s power play is a strength, but injuries have gutted their top six. Alex Tuch and Tage Thompson carry the scoring load. Transition defense remains the biggest concern against a Colorado team that punishes slow resets. Buffalo needs an efficient night from its second and third lines to stay close.

Injuries and Conditions

Colorado Injuries

• Valeri Nichushkin, lower body, doubtful
• Samuel Girard, upper body, out
• Joel Kiviranta, lower body, out
• Jacob MacDonald, hip, out
• Logan O’Connor, hip, out
  Visit the full Colorado Avalanche injury report for updates.

Buffalo Injuries

• Jiri Kulich, blood issues, out
• Jason Zucker, illness, out
• Zach Benson, lower body, possible return
• Justin Danforth, lower body, out
• Rasmus Dahlin, personal, out
  Check the Buffalo Sabres injury report before placing bets.
• Ball Arena is indoors, so no weather variables.

Best Bets and Prediction

Buffalo is 0-3 straight up in its last three. Colorado is 3-0 in its last three and has covered in four of five. Avalanche games have gone under in eight of their last ten.

Projected score: Avalanche 4, Sabres 2
Best bet: Avalanche moneyline
Secondary lean: Under 6.5

ScoresAndStats Handicappers and Picks

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