Carolina Panthers vs Los Angeles Rams Picks and Predictions November 30th 2025

Game Preview Los Angeles Rams @ Carolina Panthers

The Los Angeles Rams are the hottest team in the NFC, riding a six-game winning streak. They will visit the Carolina Panthers on Sunday, November 30, 2025, at Bank of America Stadium in Charlotte. The Panthers, currently at 6-6, look to stay in playoff contention, while the 9-2 Rams aim to maintain their dominance atop the NFC West.

Los Angeles has allowed a league-low 16.3 points per game, and Matthew Stafford leads the league with 30 touchdowns and only two interceptions. The Panthers, meanwhile, are dealing with key defensive injuries and have scored in single digits in three recent losses.

Odds and Key Information

Category	Detail
Matchup	Los Angeles Rams @ Carolina Panthers
Venue	Bank of America Stadium, Charlotte, NC
Date & Time	Sunday, November 30, 2025, 1:00 PM ET
TV Coverage	FOX
Rams Moneyline	-621
Panthers Moneyline	+457
Rams Spread	-10.5 (-107)
Panthers Spread	+10.5 (-113)
Total Over/Under	45.0 (-110/-110)

Los Angeles Rams Outlook

The Rams have won six straight games and lead the NFC West. Quarterback Matthew Stafford is playing at an MVP level, having thrown 30 touchdowns and just two interceptions. Davante Adams continues to dominate with nine touchdown receptions over the last five games, tying a franchise record.

Los Angeles also brings a tough defense, ranking seventh in opponent passing interceptions. With players like Puka Nacua and Kyren Williams contributing in both the air and ground game, the Rams are one of the most balanced teams in the NFL. Injuries are a factor, but the return of key players such as Tutu Atwell and Ahkello Witherspoon provides a boost.

Carolina Panthers Outlook

The Panthers dropped a tough 20-9 game to the 49ers and have lost back-to-back home games. Bryce Young is showing signs of progress but has thrown multiple interceptions in recent matchups. The rushing game, however, remains solid with Rico Dowdle ranking sixth in rushing yards.

Carolina’s defense is battling injuries, with Jaycee Horn in concussion protocol and multiple secondary players out or questionable. The Panthers will need to rely on young replacements in the secondary and avoid giving up big plays if they hope to slow down the Rams’ offense.

Key Matchup

Key Area	Edge
Quarterback Play	Rams (Matthew Stafford: 30 TDs, 2 INTs)
Defensive Takeaways	Rams (7th in INTs)
Rushing Attack	Panthers (Rico Dowdle: 871 rushing yards)
Receiving Threats	Rams (Adams, Nacua)
Injuries	Panthers (Major secondary issues)

Betting Trends

• Rams are 11-1 SU as favorites in their last 12 games.
• Rams are 6-0 SU in their last 6 games.
• Rams are 10-2 ATS as favorites in their last 12.
• Panthers are 5-0 ATS after a loss in their last 5.
• Panthers are 4-0 SU after a loss in their last 4.
• Panthers are 9-5 O/U as underdogs in their last 14.

The Lean

The Rams are favored by 10.5 points, and they’ve covered in 83% of recent games as favorites. Their offense is ranked top-10 in most categories, while their defense has kept opponents to a league-low 16.3 points per game. Our model projects a final score of Rams 31, Panthers 17, supporting the Rams to cover the -10.5 spread.

With the total set at 45.0, the projection of 48 points suggests a lean toward the over, especially considering Carolina’s tendency to hit the over as underdogs.

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