Xavier Musketeers vs St. John’s Red Storm Picks and Predictions January 24th 2026

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St. John’s Red Storm heads to the Cintas Center to face the Xavier Musketeers on Saturday afternoon, with tipoff set for 1:30 PM ET in Cincinnati. This Big East matchup has clear betting implications, with the St. John’s Red Storm entering as the favorite and hoping to maintain momentum in a tight conference race. Xavier Musketeers, meanwhile, are in desperation mode—trying to defend their home floor and stay afloat in the middle of the standings. The Red Storm are laying -8.5 on the spread and -424 on the moneyline, while the Musketeers are priced at +310 to pull off the upset. The total has been bet up slightly and currently sits at 163.5, suggesting a fast-paced, high-scoring game. With St. John’s looking to extend its win streak and Xavier seeking a bounce-back spot, this game sets up with multiple angles for bettors to attack.

St. John’s vs Xavier Odds

Here are the current lines for Saturday’s matchup. Always shop the latest college basketball odds for the best price and monitor movement as tipoff approaches.

TeamMoneylineSpreadTotal
St. John’s-424-8.5 (-118)O 163.5 (-113)
Xavier+310+8.5 (-108)U 163.5 (-110)

St. John’s Betting Form

The St. John’s Red Storm are rolling. Pitino’s squad has won five of their last six, and they’ve covered in four of those. They’re getting it done by overwhelming opponents in transition, crashing the offensive glass, and forcing turnovers at a high rate. Their pace ranks among the top 25 in the nation, and they’re constantly looking to push after both makes and misses. That tempo fuels their offense, which relies on dribble drives and kick-outs to stretch the floor and create paint touches.

Defensively, they’re volatile. Their aggressive perimeter pressure creates chaos, but it can also lead to breakdowns if the first line doesn’t connect. They’ve been vulnerable to teams that move the ball well and can hit spot-up threes, but Xavier hasn’t been consistent enough from deep to scare you off. St. John’s also rebounds well defensively and ranks top-20 in offensive rebounding rate, which helps mask some of their erratic half-court sets.

Injury-wise, they’ve been healthy, but availability always matters—so keep an eye on the St. John’s injury report in case of any late-breaking news in the backcourt. They rely heavily on their guard depth to fuel tempo and handle pressure.

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Xavier Betting Form

The Xavier Musketeers are in a funk. They’ve dropped three of their last four and haven’t looked sharp, especially late in games. Still, they’ve been more competitive at home, where they’re 7–3 this season. At the Cintas Center, they’ve been able to slow games down, get into their sets, and let the crowd carry them through momentum swings. The problem is they haven’t been able to string stops together consistently.

Xavier plays at a slower pace and doesn’t shoot a high volume of threes, which hurts them when they fall behind. Their offense runs through ball screens and post touches, but the ball can get sticky. They’re not getting many easy buckets, and their free-throw rate has dropped in conference play. On the glass, they’re getting outworked, particularly on the defensive end where second-chance points have become a problem.

The rotation’s been a bit banged up lately, and depth has become a concern. A few key bench contributors have been in and out of the lineup, so you’ll want to monitor the Xavier injury report before locking in any action. Fatigue could be an issue if they fall behind early and have to chase.

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St. John’s vs Xavier Matchup Breakdown

Stylistically, this is a clash. St. John’s thrives on pace, rim pressure, and offensive rebounding. Xavier wants to slow the tempo, run sets, and control possession length. Whichever team dictates the rhythm early will likely set the tone for bettors on both side and total. But based on form, it’s hard to see Xavier flipping the tempo battle unless they completely dominate the glass and take care of the ball—two areas they’ve struggled with lately.

Shot profile favors the Red Storm. They take more rim attempts, get to the line more often, and convert in transition. Xavier takes more midrange looks and doesn’t get enough clean threes to stretch defenses. Turnovers are another major edge for St. John’s. They force nearly 16 per game and score efficiently off live-ball mistakes. If Xavier coughs it up early, this could snowball.

Late-game execution has been a weakness for Xavier, especially at the free-throw line. In close games, they’ve missed crucial front ends or split too many trips. St. John’s isn’t elite from the stripe either, but they generate so many more attempts that the volume usually covers the variance. That matters for spread bettors in the -8.5 range and Over bettors relying on late fouling.

If you want to sharpen your approach to matchups like this, our college basketball betting guide breaks down how tempo and shot profile can uncover spread and total edges in overlooked spots.

St. John’s vs Xavier Predictions and Best Bets

I lean St. John’s -8.5 here. They’re playing with confidence, have the better overall metrics, and can control this game with pressure and pace. Xavier may hang for a bit, but their scoring droughts and lack of rebounding make it hard to trust them to stay within the number, even at home. Unless the injury news breaks in their favor, it’s Red Storm or pass on the side.

As for the total, 163.5 is high but not crazy. St. John’s tempo and efficiency in transition can push this Over even if Xavier plays at a crawl. The key is whether Xavier can score enough to hold up their end. I lean Over slightly because of the expected foul game late and St. John’s pace, but it’s not the strongest angle.

If you’re looking for something secondary, consider the first-half Over. St. John’s tends to come out hot, and Xavier’s defensive adjustments usually don’t kick in until halftime.

Best Bet: St. John’s -8.5 (-118).

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