The #19 Vanderbilt Commodores travel to Columbia tonight for a high-stakes SEC showdown against the Missouri Tigers. Tip-off is set for 9:00 PM ET at Mizzou Arena, with the broadcast available on SEC Network. Vanderbilt (21-4) is currently one of the most resilient teams in the country, having won five of their last six games despite significant backcourt injuries. Missouri (17-8) remains a formidable opponent at home (13-4) and is desperate for a signature Quad 1 win to solidify their NCAA Tournament resume.
Vanderbilt vs Missouri Odds
Vanderbilt opens as a road favorite, a testament to their #14 nationally ranked scoring offense and consistent performance as a betting favorite (18-2 SU). For those looking for real-time shifts, check the latest college basketball odds.
| Team | Moneyline | Spread | Total |
| Vanderbilt | -190 | -4.5 (-105) | O 152.5 (-110) |
| Missouri | +151 | +4.5 (-121) | U 152.5 (-110) |
Vanderbilt Betting Form
Vanderbilt is coming off a statement 82-69 win over Texas A&M. Tyler Nickel has been the primary beneficiary of the team’s “next man up” mentality, fresh off a 25-point outing. The Vanderbilt Commodores stats and results highlight an elite offense that averages 88.4 points per game and ranks 13th nationally in points per possession.
The Vanderbilt injury report remains the biggest storyline. The Commodores have been without star guards Duke Miles (16.6 PPG) and Frankie Collins (11.2 PPG) for several weeks due to knee procedures. While Coach Mark Byington indicated that Duke Miles is “attacking his rehab” and could return soon, he remains questionable for tonight. In their absence, sophomore Tyler Tanner has emerged as a star, averaging 25.8 points over a recent five-game stretch. Vanderbilt’s ability to maintain a 10-2 road record despite these absences shows incredible tactical flexibility.
Missouri Betting Form
Missouri is looking to bounce back from an 85-68 loss to Texas. Mark Mitchell continues to lead the Tigers, averaging 17.2 points per game, while Jayden Stone (14.9 PPG) provides veteran stability in the backcourt. The Missouri Tigers schedule and stats show a team that shoots a solid 49.2% from the field and ranks 22nd in home two-point shooting percentage.
However, the Missouri injury report is also a factor. The Tigers have been playing without 6-foot-11 forward Jevon Porter (leg), who is listed as questionable/unlikely for tonight after missing 13 consecutive games. On a positive note, guard Sebastian Mack (7.0 PPG) is off the injury report and expected to play after a four-game absence. Missouri recently adjusted their starting lineup, moving T.O. Barrett and Trent Pierce into starting roles to provide more length and defensive versatility.
Vanderbilt vs Missouri Matchup Breakdown
This game features a significant contrast in pace. Vanderbilt plays at a lightning-fast tempo, ranking 33rd in the nation in possessions per game. Conversely, Missouri prefers a more deliberate approach (ranking 251st in pace). The outcome will largely depend on which team can dictate the rhythm; if Vanderbilt forces Missouri into a track meet, the Tigers may struggle to keep up with the Commodores’ 56.5% effective field goal percentage.
Missouri’s best path to a win is exploiting Vanderbilt’s thin rotation. With Vanderbilt potentially missing two of its best perimeter defenders, Missouri’s Mark Mitchell should have opportunities to attack the paint. However, the Tigers’ defense ranks 302nd in opponent three-point shooting (36.1%), which is a major red flag against a Vanderbilt team that shoots 37.5% from deep on the road.
Vanderbilt vs Missouri Predictions and Best Bets
While Mizzou Arena is a tough place to play, Vanderbilt has proven they can win short-handed on the road. Tyler Tanner and Tyler Nickel are playing with high confidence, and the Commodores’ offensive efficiency is simply too high for a Missouri defense that has struggled to guard the arc. The 4.5-point spread feels narrow for a team with Vanderbilt’s scoring ceiling.
Regarding the total, the line of 152.5 is a battle between Vanderbilt’s pace and Missouri’s slow-down tactics. Given Missouri’s defensive struggles and Vanderbilt’s tendency to push the ball, this game has a high probability of turning into a shootout.
Best Bet: Vanderbilt -4.5 (-105).
NCAAB Picks and Handicappers on ScoresAndStats
For more expert analysis on tonight’s SEC slate, you can view today’s college basketball picks. Our platform features some of the top sports handicappers with verified records in conference play.
Check the handicapper leaderboard to find the most profitable experts over the last 30 days. For those looking for a long-term strategy, you can buy premium NCAAB picks for full game breakdowns. As March approaches, don’t forget to track the college basketball championship odds to see where the Commodores stand in the title hunt.



