New York Knicks vs Indiana Pacers Picks and Predictions March 17th 2026

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The New York Knicks return to Madison Square Garden tonight with a clear mission: maintain focus. Despite a three-game winning streak, the Knicks have survived major scares against lottery-bound teams recently, including an 18-point comeback against Utah and a narrow escape against a depleted Warriors squad. Now sitting in third place in the Eastern Conference with a 44-25 record, New York looks to complete the season series sweep against a team that was once their greatest postseason hurdle.

The Indiana Pacers, meanwhile, are enduring a historically difficult season. At 15-53, they hold the worst record in the NBA and are currently mired in a 13-game losing streak—tying a franchise record. The loss of Tyrese Haliburton to a torn Achilles in last year’s playoffs essentially derailed their 2026 campaign before it began. With an 7:30 PM ET tip-off on MSG, Indiana faces the daunting task of stopping their slide in one of the league’s most hostile environments.

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Indiana Pacers vs New York Knicks Odds

The oddsmakers aren’t expecting a close contest, installing New York as massive double-digit favorites. You can track any late-breaking movement on the latest NBA odds page.

TeamMoneylineSpreadTotal
Indiana Pacers+810+16.5 (-110)O 224.5 (-110)
New York Knicks-1350-16.5 (-110)U 224.5 (-110)

Indiana Pacers Betting Form

Indiana is currently in “evaluation mode,” as head coach Rick Carlisle recently put it. The injury report is a laundry list of key contributors, with Pascal Siakam (knee) and Andrew Nembhard (ankle) missing time recently. In their 134-123 loss to Milwaukee on Sunday, the Pacers were forced to start two-way player Jalen Slawson against Giannis Antetokounmpo. While Jarace Walker has shown flashes—putting up 14.3 PPG over his last 20 games—the lack of veteran stability has led to frequent second-half collapses.

The Pacers’ offense has struggled to find a secondary creator without Haliburton, and they’ve been particularly vulnerable on the glass. For a complete look at their betting trends and recent box scores, visit the Indiana Pacers stats and results page. To see who will actually suit up tonight, check the Indiana Pacers injury report.

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New York Knicks Betting Form

The Knicks are winning, but head coach Mike Brown isn’t satisfied. “We can play better,” Brown said following the 110-107 win over Golden State. New York’s 116.9 points per game ranks 10th in the league, but it’s their rebounding (+5.0 margin) that truly defines them. Karl-Anthony Towns (11.9 RPG) and Mitchell Robinson provide a physical presence that few teams can match. However, Jalen Brunson is currently questionable with right ankle soreness/injury management, which could shift the offensive burden to Landry Shamet and Mikal Bridges.

New York has been a dominant home team this year, but they have a tendency to “play down” to their competition lately. They allowed the Jazz to build an 18-point lead and let a Curry-less Warriors team within one point in the final minutes. You can monitor their home-court performance metrics at the New York Knicks schedule and stats page and stay updated on Brunson’s status via the New York Knicks injury report.

Indiana Pacers vs New York Knicks Matchup Breakdown

This matchup is a study in contrasts. The Knicks are elite on the boards (4th in the league), while the Pacers are essentially playing an experimental frontcourt due to injuries. If Mitchell Robinson and KAT can dominate the offensive glass, New York will likely generate enough second-chance points to put this game away early. Indiana’s only hope is to turn this into a high-variance shooting contest; they showed they could hang with Milwaukee for a half by shooting the lights out, but maintaining that efficiency for 48 minutes has been their Achilles’ heel.

Handicapping a 16.5-point spread requires looking at motivation. The Knicks are frustrated with their recent lack of focus and might use this “get right” game to make a statement. Conversely, if Brunson sits, the New York offense can become stagnant, potentially allowing Indiana to stay within the massive number. For more on situational betting like large home favorites, refer to our NBA betting guide.

Indiana Pacers vs New York Knicks Predictions and Best Bets

While a 16.5-point spread is massive for any NBA game, the Pacers are currently fielding what is effectively a G-League rotation in several key spots. New York is 2-1 against the Pacers this season, but those games were played when Indiana was significantly healthier. The Knicks’ coaching staff has been vocal about “figuring it out,” and I expect them to come out with defensive intensity to avoid another nail-biter.

Our computer models project a final score in the neighborhood of Knicks 124, Pacers 105. This suggests New York has enough firepower—even if Brunson’s minutes are limited—to cover the number. I also like the Over 224.5; the Pacers have given up 130+ points in their last outing, and New York’s secondary scorers like Shamet and Bridges are due for a high-volume night.

Best Bet: New York Knicks -16.5 (-110).

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