The 2022 MLB season is heating up, and there are plenty of games on the schedule on Wednesday, June 15th. A long list of games means that you will find some great betting options, including looking at underdogs.

Best MLB Bookies

Baseball is a sport in which underdogs are pretty common each day, and there are always going to be some good options to look at. Here are the best MLB moneyline underdog picks for Wednesday.

Tampa Bay Rays at New York Yankees

Rays vs. Yankees Prediction

Best Bet: Rays ML (+118)

The Tampa Bay Rays and New York Yankees will continue their three-game series when they meet up on Wednesday night. New York won the series opener by a score of 2-0, and game two should be another low-scoring affair also.

Shane McClanahan makes this start for the Rays, and he is 7-2 with a 1.87 ERA this season. Nestor Cortes starts for the Yankees, and he is 5-2 with a 1.96 ERA.

The Yankees have a clear edge when it comes to the offensive lineups, but the Rays are a team that knows how to deal with them. Tampa Bay just continues to find ways to win games and stay in the playoff race, and that will be the case here as well.

Since a low-scoring affair is expected in this game, this is a perfect opportunity to bet on the underdog Rays. Tampa Bay can pick up a clutch hit late and steal this win over the Yankees and end the long home winning streak for New York.

MLB Odds

San Diego Padres at Chicago Cubs

Padres vs. Cubs Prediction

Best Bet: Padres ML (+100)

The San Diego Padres are road underdogs against the Chicago Cubs, and this is a betting line that simply feels way off. San Diego has won each of the first two games of this series, and they have done so pretty convincingly.

Chicago will be sending rookie Caleb Kilian to the mound on Wednesday night, and this will be just his second start of his career. Kilian was sharp against the St. Louis Cardinals in his first start, but he will have to be nearly perfect in this game.

The Cubs are just doing little right at this time, and San Diego scored 12 straight runs in a blowout win on Tuesday night. San Diego is one of the best teams in baseball, and they should have little trouble winning this game.

MLB Picks

Los Angeles Angels at Los Angeles Dodgers

Angels vs. Dodgers Prediction

Best Bet: Angels ML (+166)

The Angels and Dodgers will once again meet up in Los Angeles after the NL team picked up a 2-0 win at home in the series opener. This would have been viewed as a great matchup back in May, but the Angels are now pretty big underdogs.

The Dodgers will have Tyler Anderson on the mound in this game, and he is a perfect 7-0 on the year. Anderson has been extremely impressive so far in 2022, but he is also due for a loss at some point.

The Angels will have Reid Detmers making this start, and he already has a no-hitter under his belt this season. That Angels lineup has really been struggling of late, but it will find a way to do some damage in this game.

Take the Angels +166 as they get some revenge on the Dodgers.