MLB Picks and Parlay for Friday, May 7th

It’s time to look at the MLB schedule for Friday, May 7, and build the perfect MLB parlay. All of the teams are in action on Friday, and that gives plenty of betting opportunities.

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Betting on baseball can be a challenge, but there are some matchups that stick out on Friday. These three games seem like a lock, and here are the top MLB parlay picks for the day.

Pittsburgh Pirates at Chicago Cubs Picks

Pirates vs. Cubs Betting Trends

Best Bet: Over 7.5 Runs

The first game to focus on takes place at Wrigley Field between the Chicago Cubs and Pittsburgh Pirates. This is already the 7th matchup of the season between the NL Central rivals.

Trevor Cahill takes the mound for Pittsburgh, and he will be opposed by Zach Davies of the Cubs. Both pitchers have an ERA of over 7.0, and that’s going to lead to a high-scoring affair.

The Cubs are the 6th-highest scoring team in baseball, and Pittsburgh has hit well against the Cubs. Wind always plays a factory at Wrigley Field, but these teams are going to score runs regardless.

Start off your MLB parlay by taking the OVER 7.5 total runs in this game between Pittsburgh and Chicago.

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Colorado Rockies vs. St. Louis Cardinals Picks

Rockies vs. Cardinals Betting Trends

Best Bet: Cardinals -1.5

The Cardinals and Rockies begin a weekend series on Friday night at Busch Stadium. Nolan Arenado faces his former team for the first time, and the Cardinals have been rolling of late.

Colorado will send Austin Gomber to the mound, and he was acquired from St. Louis in the Arenado deal. The young lefthander has struggled this season, and this isn’t going to be an easy test either.

St. Louis will have Jack Flaherty on the mound, and the ace of the staff is a perfect 5-0 this season. Colorado struggles to hit on the road, and Flaherty could carve up that lineup in this game.

The Cardinals do have some holes in their lineup, but they also have plenty of power in the middle. St. Louis should put up plenty of runs in this game, and Flaherty will take care of the rest.

The Rockies are just not a good road team, and they can’t keep this one close. Take the Cardinals -1.5 with your second pick in the parlay.

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Chicago White Sox -1.5 at Kansas City Royals Picks

White Sox vs. Royals Betting Trends

Best Bet: White Sox -1.5

The Royals host the White Sox in a clash of AL Central rivals on Friday night. This division is wide open this season, and both of these teams are near the top of the division.

Carlos Rodon starts for Chicago on Friday, and he is 4-0 with an 0.72 ERA to begin the season. The White Sox also have a great bullpen and can shut a game down with a lead.

Kansas City counters with Brad Keller, and things have not gone well for him this season. The Royals have been on a skid of late, and facing the White Sox won’t help.

Chicago is dealing with some injuries, but that lineup is still loaded with talent. Look for the White Sox to pull away in this game as Rodon and that offense lead the charge.

Take the White Sox -1.5 over the Royals to finish up your MLB parlay.

About the Author
Kyle Parker
Kyle Parker
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Kyle’s goal is to break down games and betting performances with sharp, experience-backed analysis built on over 25 years in the industry. As a longtime bookie, oddsmaker, and line mover, he brings a unique perspective to every recap—highlighting key trends, standout plays, and what bettors can learn moving forward.