NFL Previews 
MLB Previews 
NBA Previews 
NHL Previews 
Soccer Previews 
Game Preview: Kansas City Chiefs vs Buffalo Bills
The Kansas City Chiefs visit the Buffalo Bills on Sunday afternoon in a matchup that has defined the AFC landscape for much of the past five seasons. Kickoff from Highmark Stadium is set for 4:25 PM ET on CBS.
Both teams enter Week 9 in the middle of the AFC playoff race. Kansas City (5-3) sits seventh in the standings, while Buffalo (5-2) holds the fifth seed. Despite their position, both remain among the top contenders in the conference and for the Super Bowl. See full futures in the Super Bowl odds and predictions blog.
Follow Daily Best Bets and System Plays
Consistency Wins — Start Now
Opening Lines and Market Snapshot
- Spread: Chiefs -2.0 (-110) | Bills +2.0 (-111)
- Moneyline: Chiefs -131 | Bills +110
- Total: 52.5 (Over -108 | Under -111)
For updated movement and betting splits, visit the NFL odds board and compare live market data.
Kansas City Chiefs Outlook
The Chiefs are trending upward, winning five of their last six games after a slow start. Patrick Mahomes continues to lead one of the league’s most dynamic offenses, throwing for 299 yards and three touchdowns in a 28-7 win over Washington last week.
Kansas City ranks first in passing yards (2,099) and fourth in total offense, averaging 415.8 yards per game since Week 4. Travis Kelce remains Mahomes’ top target, while rookie receiver Rashee Rice has emerged as a reliable weapon in the slot.
Defensively, Kansas City has stabilized, ranking fourth in points allowed. They’ve held opponents under 20 points in four of their last six games.
Chiefs Injury Report
Deon Bush (S) – Out (Achilles)
Isiah Pacheco (RB) – Questionable (Knee)
Trey Smith (G) – Questionable (Back)
Janarius Robinson (DE) – Out (Foot)
Felix Anudike-Uzomah (DE) – Out (Hamstring)
Eric Scott Jr. (CB) – Out (Knee)
Josh Simmons (OT) – Questionable (Personal)
Buffalo Bills Outlook
The Bills dominated Carolina 40-9 last week behind James Cook’s 216-yard, two-touchdown rushing performance that earned him AFC Offensive Player of the Week. Josh Allen managed the offense efficiently with 163 passing yards and a touchdown, while Buffalo’s defense generated four turnovers.
Buffalo ranks second in scoring offense and fifth in takeaways, showing a balance that few AFC teams can match. Their defensive front — featuring Greg Rousseau and Ed Oliver — recorded seven sacks last week and could pressure Mahomes throughout.
Josh Allen has historically performed well against Kansas City in the regular season, owning a 4-1 mark with 24 total touchdowns across their last five matchups.
Bills Injury Report
Matt Milano (LB) – Questionable (Pectoral)
DaQuan Jones (DT) – Questionable (Calf)
Ed Oliver (DT) – Out (Bicep)
Gabe Davis (WR) – Out (Knee)
Taylor Rapp (S) – Out (Knee)
Tyler Bass (K) – Out (Groin)
Terrel Bernard (LB) – Questionable (Ankle)
Key Storylines
- Josh Allen and Patrick Mahomes meet for the 10th time since 2020, with Buffalo 4-1 in regular-season meetings and Kansas City 4-0 in the postseason.
- Kansas City’s passing attack ranks top-three in the NFL, while Buffalo’s pass rush has recorded 19 sacks over the past four games.
- The winner stays in striking distance of the AFC’s top seed as playoff positioning tightens.
Betting Trends
- Chiefs are 10-2 ATS as favorites since 2024.
- Bills are 7-1 straight up in their last eight home games.
- Over is 4-0 in Buffalo’s last four games with totals above 50.
- Chiefs are 3-0 SU in their last three overall.
Explore more team-specific numbers in the NFL expert betting guide.
Experience Premium Access Without Limits
Every Sport. Every Season. Every Pick.
Prediction
Both offenses are capable of big plays, but Buffalo’s defensive front gives them the edge at home. Expect another tight, high-scoring contest between Mahomes and Allen — and another chapter in one of the NFL’s most compelling rivalries.
Projected Score: Bills 30, Chiefs 27
Best Bet: Bills +2.0 (-111)
Total Lean: Over 52.5 (-108)
Scores and Stats Handicappers
Compare verified NFL experts, profits, and win percentages on the Scores and Stats Handicappers leaderboard. Follow top performers for premium Week 9 picks across all NFL matchups.
