If you’re into NFL betting, the chances are good that you like stacking up your bets and going for it all with big NFL parlays. Hopefully you realize it’s a risky proposition, but I am right there with you in terms of it being fun and potentially very rewarding.

Provided you know your limits and try to piece together logical NFL parlay picks, this can lead to a lot of big wins. Of course, you want to target the best NFL Week 7 picks out there, ideally correlate your bets to some degree, avoid crazy risks, and also limit just how many legs you add to one bet slip.

Those are just a few rules to consider living by, and I’ll apply most of them to my top NFL parlay for week 7. Want even more help before placing your bets this week? Stop by our Week 7 NFL predictions to see what else we like for the latest batch of NFL games.

NFL Picks and Parlays

Monitor the NFL odds throughout the week. As the odds change, the parlay payouts will change as well. 

Team	Odds	Payout Per Leg
Panthers vs. Jets Over 42	-105	$95.24
New England Patriots	-330	$154.40
Chicago Bears	-235	$262.66
New York Giants	+7 (-110)	$592.35

Betting on the NFL can be a fickle thing, as you often can have two conflicting sides of an argument, and yet both sound pretty good. A good example is the Denver Broncos vs. New York Giants game, as I fully expect the Broncos to take care of business at home, but I think the G-Men are good enough to keep this game within a touchdown, too.

I like all of these other bets just as well, and when you combine them all, you’re looking at a $592 return for every $100 you risk. Obviously you still need four picks to hit together here, so if you don’t like 1-2 picks, feel free to cut them off of your parlay or simply attack these bets individually.

You can also aim a bit higher by including any of my Week 7 NFL underdog picks to give this parlay a boost, but I am shooting for a win with four bets I feel really good about. If you need some reasoning as to why I like each pick, read on.

Of course, I’m just one voice here, you can get extra NFL betting advice by leaning on the top handicappers today!

NFL Parlay Picks

The following is our best parlay NFL picks for Week 7: 

NFL Parlay Pick 1: Panthers vs. Jets Over 42 (-105)

The first leg of my week 7 NFL parlay is going to be the Carolina Panthers vs. New York Jets game hitting the Over. New York’s defense actually looked pretty darn good last week, as they played the Denver Broncos overseas and lost 13-11 in a truly ugly affair.

I’m not totally sold on their defense just yet, however, especially since it had been giving up quite a bit of production countless times over their previous five games. That could happen again in this spot, as the Carolina Panthers have looked better offensively in recent weeks.

On the flip side, Justin Fields can’t possibly get worse than what we saw out of him and this Jets offense in week six. They have a much softer matchup this time around, as Carolina gave up a good amount of points to the Dallas Cowboys last week and have not been consistent on the defensive side of the football.

All things told, both offenses do have some upside and neither defense is scary. This game total feels awfully low and I think we can get to at least 43 points in this spot.

NFL Parlay Pick 2: New England Patriots ML (-330)

Next up are the New England Patriots to get a nice road win against the Tennessee Titans. The Titans lucked into their lone win of the season two weeks ago, and that required some epic absurdity going their way.

Tennessee unsurprisingly struggled in week six, going right back to being a team that can’t consistently stop anyone, and has major issues scoring the ball on offense. Titans quarterback Cam Ward appropriately gave himself an F grade, and I don’t think many people would disagree with him.

As bad as the Titans are, I am a bit surprised the Pats are not bigger favorites. Two weeks ago they downed the previously undefeated Buffalo Bills, and last week they continued to look sharp in a win over the New Orleans Saints.

New England is one of the more shocking teams so far in 2025, but they are starting to look like the real deal. On top of that, there’s a fun narrative attached to this one, as former Titans head coach Mike Vrabel will be eager to beat the team that fired him not too long ago.

From top to bottom, the Patriots feel like a slam dunk here. I know their -330 moneyline doesn’t elevate this NFL parlay to extraordinary heights, but it does enough and should honestly be a lot thicker than it is.

NFL Parlay Pick 3: Chicago Bears ML (-235)

My third leg of this week’s NFL parlay is the Chicago Bears to be the next team to upend the New Orleans Saints. Much like Tennessee, the Saints did well to somehow win a game a couple of weeks ago, but it could be a while before they manage to do that again.

New Orleans is at home here and to be honest, quarterback Spencer Rattler has looked pretty good. Unfortunately, consistency is still not a strong suit of anyone on this team, while the Saints don’t pose much of a threat to opposing offenses, either.

There could be enough here for these two sides to engage in a shootout in the dome, but I have more faith in the Chicago Bears simply finding a way to get the win. They got off to a rough 0-2 start, but they haven’t lost since and are starting to round into form as week seven approaches.

Caleb Williams still tends to be pretty hit or miss, but when he’s on he looks like the real deal, and head coach Ben Johnson appears to know what he’s doing. On top of that, Chicago’s ground game exploded last week and their underrated defense could give the Saints serious problems in this one.

The Bears could be one of the sneakier NFL teams to make the playoffs this year, but for the time being, they’re a bit of a steal at their -235 moneyline in week seven.

NFL Parlay Pick 4: New York Giants +7 (-110)

Lastly, we have the New York Giants beating a 7-point spread on the road against the Denver Broncos. This is admittedly a little dicey, seeing as the Broncos are now 4-2 and have delivered some pretty nasty defensive performances lately.

While the Broncos are definitely the better team and at home, the Giants have injected new life into their offense by turning to rookie sensations Jaxson Dart and Cam Skattebo. These guys are still a bit raw, but they are immensely talented and have zero fear. It really wouldn’t be all that shocking to see them march into Denver and give the Broncos a serious fight.

After all, let’s not forget that Denver has gotten tripped up twice this year, while just last week they struggled on offense and barely beat a winless Jets squad.

New York is down a stud in Malik Nabers, but they have a strong pass rush that can get after Bo Nix, and their dynamic offense could move the ball and put up some points in this matchup. Denver is still a really good bet to get the win at home, but spotting the Giants seven points has me interested in them as a solo bet and as part of my week 7 NFL parlay picks.

NFL Parlay Total Payout

• Panthers vs. Jets Over 42 (-105)
• New England Patriots ML (-330)
• Chicago Bears ML (-235)
• New York Giants +7 (-110)

This is the complete NFL parlay for week 7, although you might be able to find better NFL odds for these games, depending on which sports betting sites you use.

No matter where you go to bet on the NFL, though, the prices should be somewhat similar. New York is still going to be roughly a touchdown underdog, and so on. I actually almost slid them into my week 7 NFL upset picks, but intentionally avoided any cross-over this week.

The G-Men are undeniably the riskiest bet on this slip, but you don’t need them to win. They have looked pretty good in recent weeks, with a blowout win over the Philadelphia Eagles showing everyone what they’re capable of recently. My favorite bet here is naturally the Pats to take care of business, in the event you want to hammer the best pick and run.

If you are loving these NFL parlay picks, then check out our College Football parlays of the week and double down on this weekend’s gridiron action.