Miami at Clemson Best Pick, Prediction and Odds

No. 6 Miami visits Clemson on Saturday 3 October, at Memorial Stadium (Clemson, SC), with kickoff at 12:00 AM ET. Miami is a 17.5-point favorite. Rankings are from the AP poll for week 4.

This is the early page for the game: what is already known. Our full prediction, with the call and the numbers behind it, goes up on this page before kickoff.

The two teams in 2026, through 23 September

Miami is 3-0 this season, 2-0 in the Atlantic Coast Conference. Most recently it beat Wake Forest 33-20 on the road on 18 September. It has scored 51.7 points a game and allowed 11.0.

Clemson is 2-1 this season, 1-0 in the Atlantic Coast Conference. Most recently it beat North Carolina 28-20 at home on 19 September. It has scored 20.0 points a game and allowed 26.0.

Last season

Miami went 13-3 in 2025, scoring 30.9 points a game and allowing 14.8. Its season ended with a loss against Indiana, 27-21.

Clemson went 7-6 in 2025, scoring 27.2 points a game and allowing 20.5. Its season ended with a loss against Penn State, 22-10.

The early line

At DraftKings, read 24 September 2026, Clemson is +17.5 after opening at +7. The total is 50.5. The moneylines price Clemson to win 13.7% of the time, with the margin removed.

Lines move through the week. The full prediction reads them again on the day it goes up.

The teams

The Miami Hurricanes and Clemson Tigers team pages hold both schedules and last season’s results. Every game this week is on our college football predictions page.

Miami at Clemson, Saturday 3 October, 12:00 AM ET, at Memorial Stadium (Clemson, SC). Results: ESPN, read 24 September 2026. Line: DraftKings via ESPN, read 2026-09-24 05:06 UTC. Rankings: 2026 NCAA Football Rankings – AP Poll Week 4.