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Week 13 of the 2025-26 NFL season is shaping up to be a crucial week down the stretch run of the regular season. Will some of these holiday games make our parlay card?
We came up short in Week 12 after the Philadelphia Eagles had a meltdown against the Dallas Cowboys. Philly was up 21 points and we were looking great for winning this four-leg parlay ticket. Then the 4th quarter came, and the Eagles blew it. That would’ve been a second straight parlay win if Philly didn’t lose.
In Week 11, we nailed a four-leg parlay card that doubled our investment. That ticket included the Ravens, Packers, Cowboys and Texans.
This week, we’re looking at a handful of matchups that feature large lines and an Underdog covering their spread. Of our Week 13 parlays picks, we have a few Super Bowl hopefuls on our list.
With that said, parity has made NFL betting tricky at times. Fortunately, NFL parlays are one way to maximize betting value when the boards seem difficult to decipher.
After looking at the Week 13 slate of games, we have a handful of NFL picks to add to our parlay card. Let’s take a closer look at the best NFL parlays for Week 13.
NFL Picks and Parlays
| Team | Odds | Payout Per Leg |
|---|---|---|
| Kansas City Chiefs | -185 | $54.05 |
| Philadelphia Eagles | -305 | $104.56 |
| Denver Broncos | -290 | $175.10 |
| Houston Texans +4.5 | -110 | $425.19 |
Once again, we are going with three NFL teams that are favored this week and one Underdog to cover its spread. Heading into Week 13, Favorites are 125-52-1, which is a 70.6% winning percentage. In Week 12, the Favorites went 10-4 SU.
Furthermore, two of these four picks are favored as road teams. Away Favorites are 51-24-1, which breaks down to a 67.1% winning percentage. Road Favorites went 3-2 in Week 12.
Over the last month, we’ve gone 13-3 in our NFL parlay picks, which led to a winning ticket (4-0) in Week 11 and three 3-1 records for Weeks 9, 10 and 12.
With that said, make sure you continue to monitor the NFL odds throughout the week as they could shift as we get closer to kickoff, which will impact your total payout for this parlay card. For more NFL advice and picks, check out the best handicapping membership in the industry.
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NFL Parlay Picks
The following is our best parlay NFL picks for Week 13:
NFL Parlay Pick 1: Kansas City Chiefs (-185) vs. Dallas Cowboys
The Kansas City Chiefs and Dallas Cowboys will meet on Thanksgiving Day, in what could be a shootout as these teams feature the two best passing attacks. For the Cowboys, this week’s game marks their 57th appearance on Turkey Day. It’s just the 10th time that KC has gobbled up a Thanksgiving appearance.
These franchises have played against each other 12 times. Surprisingly, it’s the Cowboys with the series lead as they have a 7-5 record against the Chiefs.
Kansas City won the last time these teams played against each other. That game took place in 2021, and KC won 19-9. However, that game was at Arrowhead. When playing at Dallas, the Cowboys have won the last five games versus the Chiefs.
With that said, I do like the Chiefs in this game to win outright. Dallas might pull off the backdoor cover of a 3.5-point spread but I prefer KC’s moneyline over any other wager in this game.
The Chiefs are 6-3 SU in their last nine overall games. Additionally, they are 9-2 SU in their last 11 games against the NFC.
This difference maker in this matchup is KC’s passing attack that averages 252.3 ypg. They will face the 30th ranked pass defense in Dallas that allows 257.7 ypg. Considering that KC’s Achilles heel is their offensive line under heavy pass rush, and the fact that Dallas doesn’t get much pressure on opposing QBs, I like for Mahomes to demolish Dallas and lead KC to a win.
NFL Parlay Pick 2: Philadelphia Eagles (-305) vs. Chicago Bears
The Philadelphia Eagles and Chicago Bears will meet on Black Friday in a battle of NFC division leaders. Sure, Philly let me down last week and killed our parlay card, but I believe they will bounce back at home over the Bears.
These two historic franchises have played against each other 47 times, and it’s the Bears that lead this rivalry with a 29-17-1 series record. However, that’s where the good news ends for Chicago against Philadelphia.
The Eagles are 6-0 SU and 5-1 ATS in their last six head-to-head meetings against the Bears. Furthermore, Philly is 12-4 SU in their last 16 matchups versus Chicago. And, if that weren’t enough trends to convince you where to lay your money, the Eagles are 5-2 SU in their last seven home games versus the Bears.
Chicago features a Top 10 offense, which shouldn’t surprise anyone considering that Ben Johnson is the architect behind this unit and that this part of the Bears’ team is loaded with talent. Unfortunately, is see Chicago struggling against a stingy and angry Eagles defense that collapsed at Dallas last weekend.
On the flip side, the Bears allow 138.1 rushing yards per game which is the 5th highest average in the league. Philly’s Saquon Barkley and Jalen Hurts should be able push the Eagles’ ground game close to this mark.
I also like Hurts to have success through the air, as well. Let’s not forget that Joe Flacco threw for 470 yards against the Bears defense last month. Jaxon Dart had 242 yards before getting hurt.
Take Philly to win at home!
NFL Parlay Pick 3: Denver Broncos (-290) vs. Washington Commanders
The Denver Broncos and Washington Commanders have played against each other 16 times including Super Bowl 22. The series is tied at eight wins apiece, but the Commanders hold the Super Bowl win over the Broncos.
These teams last played against each other in 2023, and the Commanders won 35 to 33. The last time they played in Washington was 2017, which the home team won 27-11. The Broncos are just 2-4 SU when playing at Washington. Additionally, they’re only 2-5 ATS in their last seven games versus the Commanders.
With that said, these two teams are coming into the Week 13 game heading in different directions. The Commanders’ season is over with. At 3-8, and without Jayden Daniels, Washington has nothing to play for as they have no hope of making the Playoffs.
Yet, for the 9-2 Broncos, they’re fighting for the AFC West title and the no.1 seed in the AFC. Currently, they hold the top spot over the Patriots.
Denver started the season off at 1-2 before railing off eight straight wins. Washington has lost six games in a row.
The Broncos are 7-0 SU in their last seven games against the NFC and have gone 5-1 ATS in their last six November games. Washington is 0-5 ATS in their last five November games. I like for Denver to not only win this game outright, but to cover the 6-point spread as well. This spread should be over a touchdown.
Without Daniels, Washington can’t throw the ball consistently. So, they will try to run it. That won’t work against the no.3 run defense that allows only 88.5 ypg. And, they also have the no.6 pass defense which will create problems all day long for Mariota and this Washington passing game.
On the flip side, the Commanders give up 26.9 ppg (28th), 387 total ypg (31st), 137.5 rushing ypg (27th), and 249.5 passing ypg (29th). Denver will do whatever they want against this inferior Washington defense. Take the Broncos to win by at least seven to 10 points.
NFL Parlay Pick 4: Houston Texans +4.5 (-110) vs. Indianapolis Colts
This rivalry has been very lopsided historically, as the Indianapolis Colts hold 33-13-1 series lead over the Houston Texans. However, the Texans have won four of the last five meetings including three consecutive victories.
With that in mind, I am bucking the trends for the Colts in this matchup. Sure, I think this team has a good shot at winning the game outright, as they are 8-0 SU in their last eight home games but I like Houston’s elite defense to keep this game within four points so that the Texans cover the spread.
CJ Stroud will start this game if he clears the concussion protocol. He’s trending in that direction which should give Houston a huge boost on offense.
However, this game is all about the Texans’ defense going up against a strong Indy offense. The three games that Indy has lost this season, were against teams with aggressive defenses who could get after the QB and win at the line of scrimmage. That’s exactly what Houston does, as well.
The Texans sacked Josh Allen eight times last week. They feature the 4th best sack rate in the league. Furthermore, they allow the second fewest points (16.5 ppg) and the fewest total yards per game (264.3 ypg).
They have a defense that ranks 5th against the run (92.2 ypg), which should bottle up the NFL’s no.4 rushing attack featuring Jonathan Taylor. The Chiefs did that to Indy last week and pulled off the OT win.
Lastly, the Texans have the no.3 pass defense at 172.1 ypg. They can rush with just four linemen and play man across the board. With their confidence at a season high, I like the Texans to cover the 4.5-point spread and possibly even beat the Colts outright.
NFL Parlay Total Payout
- Kansas City Chiefs (-185)
- Philadelphia Eagles (-305)
- Denver Broncos (-290)
- Houston Texans +4.5 (-110)
Patrick Mahomes leads the Kansas City offense that features the no.2 passing attack up against the NFL’s 30th ranked pass defense in the Cowboys. Enough said!
The Eagles will bounce back on Black Friday against the Bears. Philly is 15-1 SU in their last 16 home games. Furthermore, they’ve gone 6-0 SU and 5-1 ATS in their last six meetings against Chicago.
The Broncos have one of the best defenses in the NFL going up against a wounded Washington offense. On the flip side, the Commanders have one of the worst-ranked defenses going up against a hungry Denver offense. This game should be a blowout in favor of the Broncos.
Last, but not least, I really like this elite Houston defense to keep the Texans within 4.5 points against the Colts. The way that this unit has played all season long, including eight sacks on Josh Allen last week, is going to give Daniel Jones a ton of issues. CJ Stroud should return to give the Houston offense a boost, as well.
If you take all four legs of this NFL parlay card, then you would score a $425.19 payout. That’s over a 4x on your initial investment. Our favorite pick of the weekend is the Denver Broncos coming off a Bye Week and facing the lifeless Washington Commanders.
Remember, to wager on this parlay card, you will need to check out the best sports betting sites and take advantage of any optimal lines, which means some line shopping could be greatly beneficial.
If you are winning with these NFL parlay picks, then check out our College Football parlays of the week and double down on this weekend’s gridiron action.
