The Best NFL Parlay Picks For The Divisional Round

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The NFL Playoffs are in full swing and fans were treated to four thrilling Wild Card games last weekend. While the final two games were boring at best, they still helped us cash in on a winning parlay card for last weekend.

In the opening round of the Playoffs, we took the Los Angeles Rams, Buffalo Bills, New England Patriots and Houston Texans to win their games outright. And, we cashed out a $415 win for every $100 wagered.

The Rams and Bills had to come from behind to win their respective games. While the Patriots and Texans both won by double digits.

Now, we turn our attention to the Divisional Round matchups and we feel great about our NFL picks for this weekend’s parlay card. First, the Rams should be able to go into Chicago and expose the Bears’ inferior defense to get the win.

Next, we like Josh Allen to fly into Denver and take down the Broncos. Last, but not least, the NFC West battle between the 49ers and Seahawks should end with a Seattle victory.

Now, that we’re one step closer to the Super Bowl, we’re looking to continue our parlay success at the top sports betting sites. That means we’re very cautious about taking Underdogs for this weekend’s NFL parlay ticket. Yet, Buffalo and Superman (Josh Allen) are the exception.

With that said, NFL betting can be tricky at times. Fortunately, NFL parlays are one way to maximize betting value when the boards seem difficult to decipher. Let’s take a closer look at the best NFL parlays for the Divisional Round.

NFL Picks and Parlays

TeamOddsPayout Per Leg
Los Angeles Rams-200$50.00
Buffalo Bills-110$186.36
Seattle Seahawks-370$292.42                

This week, we’re taking two NFL teams that are favored and one underdog. Heading into the Divisional Round, Favorites are 180-97-1, which is a 65.0% winning rate. Favorites went 2-4 SU in the Wild Card Round.

Two of our Wild Card picks are road teams: Rams at Bears and Bills at Broncos. Away teams went 4-2 during Wild Card Weekend to improve their record to 129-48-1, which is a 46.4% winning rate.

The Seahawks are our lone home pick. Home Teams went 148-129-1 with a 53.2% winning rate on the season so far.

Lastly, we are also going with one Underdog this weekend with the Buffalo Bills. Dogs finished 97-180-1 on the year with a 35.0% winning rate.

Over the last few months, we’ve gone 33-12 in our NFL parlay picks, which led to winning tickets (4-0) in the Wild Card Round and Week 11, five 3-1 records for Weeks 9, 10, 12, 15, 16, and 18, and two 2-2 splits for Weeks 13 and 14. Week 17 saw a 3-2 finish on a larger parlay ticket.

As we head deeper into the Playoffs, we haven’t had a losing record with our parlay picks in any given week of action. And, cleaning up a $400+ parlay ticket to start the Playoffs has us feeling great heading into the Divisional Round.

With that said, make sure you continue to monitor the NFL odds throughout the week as they could shift as we get closer to kickoff, which will impact your total payout for this parlay card. For more NFL advice and picks, check out the best handicapping membership in the industry.

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NFL Parlay Picks

The following is our best parlay NFL picks for the Divisional Round:

NFL Parlay Pick #1: Los Angeles Rams (-200) vs. Chicago Bears

The Los Angeles Rams (13-5) and Chicago Bears (12-6) will close out the Divisional Round this weekend as they get the Sunday, January 18, primetime spot.

The Rams come into this matchup winning a shoot out in the Wild Card Round after beating the Panthers on the road by the score of 34-31. This LA offense is the best unit left in the Playoffs and they will certainly test Chicago’s inconsistent defense.

LA scores 30.7 ppg (1st) along with tallying 395.6 total ypg (1st), 126.0 rushing ypg (7th), and 269.6 passing ypg (1st). The Rams put up 34 points and 411 total yards against the Panthers last weekend. Matthew Stafford finished with 304 yards through the air. Puka Nacua tallied 111 yards and a TD on 10 receptions.

Chicago pulled off an incredible comeback last weekend against rival Packers. However, they did allow 27 points, 421 total yards, and Green Bay’s Jordan Love finished with 323 passing yards.

With that said, you have to love LA’s chances against this Chicago defense.

The Bears rank 27th against the run as they give up 132.6 ypg. They also rank 25th against the pass (232.5 ypg) and 25th in sack rage (5.85%). Chicago has relied heavily on forcing turnovers to make up for their leaky defense.

That will not happen this weekend. Look for Stafford and company to have a big game against Chicago’s defense. And, unlike last weekend where the Bears came back from an 18-point deficit, I don’t see that happening this Sunday.

The Rams are 14-6 ATS in their last 20 games and 7-1 ATS in their last eight January matchups. Chicago is 3-10 ATS in their last 13 January games. Furthermore, LA is 11-5 ATS as the favorite and 12-5 ATS during the regular season. Chicago was 7-6 ATS in Conference games.

Give me Stafford and this high-powered offense to steamroll the Bears and head to the NFC Championship game.

NFL Parlay Pick #2: Buffalo Bills (-110) vs. Denver Broncos

We go from the closing game of the weekend, to the Divisional Round opener between the Buffalo Bills (13-5) and Denver Broncos (14-3).

Last weekend, the Bills went into Jacksonville as the underdog and pulled off a big road win. They rode the cape of Josh Allen who threw for one TD and 273 yards on 28-of-35, tallied an 80% completion percentage, put up a 108.7 rating, and finished with two rushing touchdowns.

And he did this against one of the hottest teams in the NFL who featured a stout defense that was no.1 against the run. The reward for that victory, is a trip to the Broncos who have one of the best defenses in the NFL and are coming off a Bye Week due to earning the no.1 seed.

With that said, I like Buffalo’s chances more so this week than I did heading to the Jags. First, Denver’s offense isn’t as good as Jacksonville’s is. The Broncos are just 15th in rushing (118.7 ypg) which is Buffalo’s biggest weakness on defense. Additionally, they’re just 11th in passing (223.9 ypg) and Buffalo has the best pass defense in the league.

I would also like to point out that this Denver defense is great on paper, but has had some issues against top-notch teams over the second half of the season.

They allowed 24 points against the Packers in Week 15 and won 34-26. But that game was leaning towards Green Bay before Micah Parsons went out with a torn ACL. They followed that performance up with a 34-20 loss at home against the Jaguars who demolished the Broncos. Then they beat the Chiefs and Chargers who both didn’t have their franchise QBs.

Buffalo’s offense is better than any of the teams that Denver has faced since their Week 12 Bye. The Jaguars showed how to beat this team and I expect that to happen this weekend as well.

Buffalo has one of the best rushing attacks in the league, along with ranking in the Top 5 for scoring, total yards, 3rd down conversion, 4th down conversion, and red zone scoring.

But, above all else, they have Super Man at QB. If the Bills can get another performance from their defense like they did in Jacksonville, which they get back two starters that were out last week, then the Bills are going to shock Denver and their fans.

Buffalo is 4-1 SU in their last five against Denver, 8-1 ATS in their last nine versus the Broncos, and -1 ATS in their last five at Denver. They’re also 6-0 SU in their last six AFC games and 4-1 ATS in their last five January games. Denver is 2-4 ATS in their last six games, 1-7 ATS in their last eight Saturday games, and 3-4 ATS as a home favorite.

Take the Bills to win this game due to Allen putting on another legacy-defining performance.

NFL Parlay Pick #3: San Francisco 49ers vs. Seattle Seahawks (-370)

The Seattle Seahawks (14-3) will host the San Francisco 49ers (12-5) and an NFC West clash for a shot at going to the NFC Championship game.

These two teams played in Week 18 to close out the regular season with the divisional crown and the no.1 seed in the NFC on the line. The Seahawks were able to go into the Bay Area and pick up a definitive 13-3 win.

That allowed Seattle to enjoy a bye week for the Wild Card Round, while the 49ers had to go into Philly where they pulled off an impressive upset victory by the score of 23-19.

This weekend’s Playoff game will mark the 57th meeting between these two rivals. The Seahawks lead the rivalry with a 32-234 record. However, the 49ers are 7-2 SU in the last nine meetings.

They have played against each other twice in the Playoffs with Seattle winning the 2014 NFC Championship game and the 49ers winning a 2023 Wild Card matchup.

I expect the Seahawks to break that 1-1 postseason tie by wining this weekend at home. In fact, I expect a similar 13-3 performance as was the case in the final regular season weekend.

The Seahawks are riding their dominant defense that ranks no.2 in scoring (17.2 ppg), no.5 in yardage (285.6 ypg), no.3 against the run (91.6 ypg) and no.9 against the pass (193.9 ypg).

In the two meetings this year, Christian McCaffrey has averaged 46 rushing ypg, 53.5 receiving ypg, and zero touchdowns. The Seahawks have been his kryptonite in the 2025-26 season. I expect that to continue this weekend.

And, without George Kittle (injury), this 49ers offense lacks the passing firepower to overcome this stifling Seattle defense. Combine that with a limited CMC and the 49ers offense will struggle to score points. In their two meetings this year, the 49ers averaged 10 ppg versus Seattle.

On the flip side, the 49ers defense is a liability. I give this team credit for how well they played at Philly but the Seahawks aren’t as toxic as the Eagles are on the offensive side of the ball.

Seattle’s no.9 passing offense (228.1 ypg) should find success against the 49ers no.22 pass defense (228.2 ypg) who also rank dead last in sack rate. Sam Darnold will have plenty of time to throw the ball and lead the Seahawks to victory.

Seattle is 5-0 SU in last five home games, 6-1 SU as the home favorite, 11-2 SU following a win, and 4-1 SU with a rest advantage. The 49ers are 2-2 SU as the away underdog, 3-4 SU as an underdog, and 3-3 ATS in division games this year.

NFL Parlay Total Payout

  • Los Angeles Rams (-200)
  • Buffalo Bills (-110)
  • Seattle Seahawks (-370)

The Rams feature a high-octane offense that leads the NFL in many premier offensive categories like scoring, total yards and passing yards. They face an inferior Chicago team that gave up 27 points to the Packers last week and rank near the bottom of the league in pass defense.

The Bills will need Josh Allen to play like a super hero and I can see that happening. Denver has a top-notch defense but they have struggled against elite offenses in the second-half of the season like against the Packers and Jaguars. Allen will pull off the big road upset.

Lastly, the Seahawks will win at home over a feisty but outmanned 49ers team that’s missing George Kittle and doesn’t have the firepower to defeat this stingy defense on the road.

If you take all three legs of this NFL Playoff parlay card, then you would score a $292.42 payout. That’s a 3X on your investment.  

Remember, to wager on this parlay card, you will need to check out the best sports betting sites and take advantage of any optimal lines, which means some line shopping could be greatly beneficial.

If you are loving these NFL parlay picks, then check out our College Football parlays of the week and double down on this week’s gridiron action.