Week 17 is shaping up to be one of the funnest slates of the 2025 NFL season, as key divisional clashes and playoff implications impact how we approach NFL player prop bets.

This is also a crucial week for the road to the Super Bowl, as playoff seeding comes into play and several teams are on their last leg as they try to force their way into the playoff conversation. This can make NFL betting a bit complicated, as motivation and playoff scenarios can be tough to gauge, but I tend to lean into the situations that simply make the most sense and exploit them.

My NFL picks have been on fire the last few weeks, as I got tripped up slightly (3-2) last week, but have gone 13-2 during that span. My hope is to get hot again for a crucial week, but if you want even more insight and advice, be sure to stop by our Week 17 NFL predictions.

Ready to rock? Let’s dive into my top NFL player prop bets and why I love them this week.

NFL Player Prop Odds

After going a perfect 10-0 with my NFL player prop bets over the past two weeks, we hit some snags in Week 16. That’s to be expected, but the good news is we still did well overall.

Josh Jacobs and Justin Jefferson failed to score, but those were also odd situations. Jacobs was about to score before fumbling, and then seemingly got benched. Jefferson may have had a chance to score but top quarterback J.J. McCarthy exited their game with a hand injury, too.

Luckily, we hit on JSN’s reception prop and also saw A.J. Brown and Ted McMillan both deliver. That’s a 3-2 run and considering the shenanigans with injuries, I will take the profit and move along.

Week 17 in the NFL comes at us fast, though, so we don’t have time to enjoy the wins. We don’t get a traditional Thursday Night Football setting, as there are three games on Christmas Day. I scanned the entire week of NFL betting action for the best NFL player props, and came away with the picks above.

You can take them at face value or read on for further analysis below. Want even more insight for week 17? Tap into what the top handicappers have to offer.

NFL Player Props Today

Here’s a breakdown of each prop, analyzing matchups, trends, and key factors to help you make informed NFL bets:

George Pickens – Over 6+ Receptions(-134)

Matchup: Dallas Cowboys @ Washington Commanders

Normally I’d be targeting a CeeDee Lamb prop bet, but I am going to pivot and roll with George Pickens to catch six or more passes. He did precisely that in the last game for the Dallas Cowboys and since he is presently sitting on 88 catches for the year, he and the team could be motivated to get him to the 100-catch milestone.

Nothing is guaranteed, but players and teams tend to be proactive about key milestones or records and Dallas probably wouldn’t mind having a 100-reception wide receiver for the year.

Pickens is within striking distance and he needs to average six catches per game over his final two contests. After bouncing back last week from a rough stretch, it looks like he’s back on track and should be motivated to finish the year strong.

On top of the reception milestone narrative, we know Dallas loves to throw the ball a ton and they get a very soft matchup against the Washington Commanders. The Commanders put up little resistance defensively, allowing the 11th most catches to wide receivers on the year.

Washington is simply bad at defending the pass, as they come into this one allowing the 9th most receiving yards to the position as well. Pickens should have the matchup and volume to easily get there and get us started off on the right foot on Christmas Day.

Tyler Shough – Over 210+ Passing Yards (-138)

Matchup: New Orleans Saints @ Tennessee Titans

It’s rarely fun to put a lot of trust (and money) in a rookie quarterback, but Tyler Shough appears to be quite good. He’s excelled lately and his strong play is a big reason for the New Orleans Saints getting hot to close out the year.

Shough has been on point lately, firing in at least one touchdown in five of his last seven games. He’s been even more reliable as a sheer yardage producer, too. He’s coming off a career-high 308-year passing day, and he’s safely topped this week’s prop line in five of his last six games.

In terms of role and talent, Shough is going to be in play to easily hit this prop bet. Helping him out, of course, is a friendly date with the Tennessee Titans, who are simply not very good. The Titans specifically struggle against the pass, though, as they are giving up the 10th most passing yards in 2025.

Shough can fail due to a lack of experience, but he has been straight up balling and the matchup looks fantastic. I am all for betting on him to get 210+ passing yards at these odds.

Kenneth Walker III – Anytime TD Scorer (+115)

Matchup: Seattle Seahawks @ Carolina Panthers

I also rarely feel good about confiding in Kenneth Walker III, but he blew up last week, which gives me confidence to roll with him in what looks like a pretty winnable matchup.

The Seattle Seahawks have to go on the road to take down the Carolina Panthers in what admittedly could end up being a trap game. That said, they are going to want to do anything they can to exit week 17 with a win, as they have a very tenuous hold on the NFC West and the top seed in the NFC.

Due to that, Seattle would be wise to play the matchup more than usual, especially considering the Panthers are getting eaten up on the ground. On the year they are the 9th worst run defense in terms of yardage allowed to running backs, while they’ve also given up the 6th most rushing scores to the position.

Walker could always get vultured by teammate Zach Charbonnett, but he still has five rushing scores on the year. This is a matchup play with Seattle hopefully leaning into the most attackable part of Carolina’s defense, but I love it at plus money.

Jacoby Brissett – Over 230+ Passing Yards (-175)

Matchup: Arizona Cardinals @ Cincinnati Bengals

Brissett was on fire for most of the year, but finally had a down game last week. I fully expect him to bounce back, though, as he gets a mouth-watering matchup against a bad Cincinnati Bengals defense.

Cincy has been a friend to opposing passers all year, ranking 28th in passing yards allowed and 29th in passing scores given up as well. The matchup is sublime, plus Joe Burrow and co. look to finish the year on high note, so it’s pretty likely Brissett will have to play catch up in this one.

All the narratives lead to Brissett throwing a good amount, and that’s something we’ve grown accustomed to seeing out of him in this Arizona offense. It’s led him to 200+ passing yards in every single start he’s made in 2025, while he’s topped this exact yardage total in nine of 10 games.

There is very little working against Brissett hitting the mark here. This is the fattest line of my week 17 NFL player prop bets, but that’s because it also happens to be the safest bet of the lot.

Drake Maye – Over 2+ Passing Touchdowns (-153)

Matchup: New England Patriots @ New York Jets

Lastly, we can cash in on Drake Maye’s amazing second season in the NFL. He keeps churning out big numbers and the New England Patriots keep winning games. They came from behind to shock the Baltimore Ravens last week, where Maye put up two scores in heroic fashion.

One of those scores was an absolute dime in the clutch, while Maye has been on a heater all year long. He’s tossed at least one touchdown in 13 of 15 starts, and he enters week 17 with 25 touchdown passes to his name. Along the way he’s met this specific two-score mark 10 times, too.

Maye is definitely feeling it these days and this week he gets to face the rival New York Jets. The Jets, alternatively, are most definitely not “feeling it”, as they have fallen apart defensively lately. New York has given up the 10th most passing scores in 2025 and they just allowed two through the air to New Orleans.

The Pats are massive favorites to get the win this week, so it only makes sense that their main touchdown scorer would have a pretty big hand in making that happen.

Best NFL Player Prop Picks For Week 16

• George Pickens Over 6+ Receptions (-134)
• Tyler Shough Over 210+ Passing Yards (-138)
• Kenneth Walker III Anytime TD Scorer (+115)
• Jacoby Brissett Over 230+ Passing Yards (-175)
• Drake Maye Over 2+ Passing Touchdowns (-153)

That does it for my top NFL parlays for week 17. I am very high on each of these picks, but I do want to stress two things; make sure you get the best possible NFL odds for all of these props, and also don’t just blindly toss them all together in a big parlay.

Parlays can be fun and conversely you would have won big with my NFL player props in two of the last three weeks by doing that; but they’re inherently risky. If you must play parlays, try cutting down the parlay and mixing safer bets with the Walker anytime TD prop.

Overall, my favorite bet is for Jacoby Brissett to clear 230+ passing yards. Last week represented his first start of the year where he failed to do so. This week the matchup and game flow both demand he gets back on track.

The rest of these week 17 NFL player props still look great and are ones I’d individually vouch for.

For the NCAAF fans out there, you can also roll with our best College Football parlays of the week for more exciting football betting action.