Oregon vs Ohio State Best Pick, Prediction and Odds

Oregon visits No. 11 Ohio State on Saturday 7 November, at Ohio Stadium in Columbus, with kickoff at 3:30 PM ET. Ohio State is a 7-point favorite. Rankings are from the AP poll for week 10.

This is the early page for the game: what is already known. Our full prediction, with the call and the numbers behind it, goes up on this page before kickoff.

The two teams in 2026, through 3 November

Oregon is 5-3 this season, 3-2 in the Big Ten Conference. Most recently it beat Northwestern 34-26 at home on 31 October. It has scored 33.2 points a game and allowed 21.4.

Ohio State is 6-2 this season, 4-1 in the Big Ten Conference. Most recently it lost to USC 30-18 on the road on 31 October. It has scored 36.6 points a game and allowed 15.5.

Last season

Oregon went 13-2 in 2025, scoring 36.9 points a game and allowing 17.9. Its season ended with a loss against Indiana, 56-22.

Ohio State went 12-2 in 2025, scoring 33.4 points a game and allowing 9.3. Its season ended with a loss against Miami, 24-14.

The early line

At DraftKings, read 3 November 2026, Ohio State is -7 after opening at -6. The total is 46.5. The moneylines price Ohio State to win 70.5% of the time, with the margin removed.

Lines move through the week. The full prediction reads them again on the day it goes up.

More college football

Our other college football predictions for the week are on the college football predictions page.

Oregon at Ohio State, Saturday 7 November, 3:30 PM ET, at Ohio Stadium in Columbus. Results: ESPN, read 3 November 2026. Line: DraftKings via ESPN, read 2026-11-03 06:55 UTC. Rankings: 2026 NCAA Football Rankings – AP Poll Week 10.