NFL Predictions Today and Picks Against the Spread
NFL Predictions Today and Picks Against the Spread · Sunday 18 October
Panthers vs Eagles Best Pick, Prediction and Odds
Panthers 2-2 and Eagles 2-2. Here is where this game stands.
The game
The Panthers visit the Eagles on Sunday 18 October at 1:00 PM ET.
Last season finished with the Eagles at 11-6 and the Panthers at 8-9. They did not meet in the data we hold, which starts with the 2025 season.
This season so far
In Week 1 the Panthers lost to the Bears 37-59. In Week 2 the Panthers beat the Falcons 34-3 on the road. In Week 3 the Panthers lost to the Browns 18-21 on the road. In Week 4 the Panthers beat the Lions 32-26. In Week 1 the Eagles beat the Commanders 24-22. In Week 2 the Eagles beat the Titans 24-20 on the road. In Week 3 the Eagles lost to the Bears 7-27 on the road. In Week 4 the Eagles lost to the Rams 20-24.
The early line
The early line has the Eagles at -6.5, the median of 3 books. The total is 43.5 across 3 books.
These are look-ahead prices, read 13 Sep 17:10 UTC, and only 3 books were quoting the spread. With the bookmaker margin removed, the moneyline makes the Eagles 72.2% to win. Expect them to move once the weeks in between are played.
Carolina Panthers at Philadelphia Eagles, Sunday 18 October at 1:00 PM ET. Prices: US sportsbooks via Nucleus, read 13 Sep 17:10 UTC. 2025 results: Nucleus, checked game by game against ESPN. Every Week 6 game: NFL Week 6 odds and predictions.