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NFL Predictions Today and Picks Against the Spread · Sunday 18 October

Bills vs Raiders Best Pick, Prediction and Odds

NFL Predictions Today and Picks Against the SpreadSun 18 Oct

Bills 3-1 and Raiders 3-1. Here is where this game stands.

The game

The Bills visit the Raiders on Sunday 18 October at 4:25 PM ET.

Last season finished with the Raiders at 3-14 and the Bills at 12-5. They did not meet in the data we hold, which starts with the 2025 season.

This season so far

In Week 1 the Bills beat the Texans 36-31 on the road. In Week 2 the Bills beat the Lions 41-31. In Week 3 the Bills beat the Chargers 24-16. In Week 4 the Bills lost to the Patriots 26-29. In Week 1 the Raiders beat the Dolphins 27-13. In Week 2 the Raiders beat the Chargers 26-14 on the road. In Week 3 the Raiders beat the Saints 35-27 on the road. In Week 4 the Raiders lost to the Chiefs 27-30.

The early line

The early line has the Raiders at +6.5, the median of 2 books. The total is 47.5 across 2 books.

These are look-ahead prices, read 13 Sep 17:10 UTC, and only 2 books were quoting the spread. Expect them to move once the weeks in between are played.


Buffalo Bills at Las Vegas Raiders, Sunday 18 October at 4:25 PM ET. Prices: US sportsbooks via Nucleus, read 13 Sep 17:10 UTC. 2025 results: Nucleus, checked game by game against ESPN. Every Week 6 game: NFL Week 6 odds and predictions.