It’s Conference Championship week! We’ve played 14 weeks – plus a Week 0 for some teams – and now it comes down to this. After Saturday is over, we will have a pretty clear picture of the 2025 College Football Playoffs and the 12 teams that will qualify for a shot at the 2026 College Football Championship.

The nine conferences that make up the Football Bowl Subdivision, or FBS, each have a championship game to determine its champion. Four of the five Group of 5 conferences will play on Friday night. The other Group of 5 conference and the remaining Power 4 conferences will all play on Saturday.

North Texas plays at Tulane on Friday. The American Athletic Conference is one of the few that play the championship game at the home of the regular season champion. It’s a huge deal for the Green Wave because they are the highest ranked Group of 5 team right now. With a win on Friday, Tulane can make the CFP.

As we have done all season, ScoresandStats NCAAF experts have checked the lines, the odds, and the trends. Let’s take a look at their picks for the best bets during conference championship weekend. And stay tuned to ScoresandStats as we help guide you through the Playoffs and bowl season.

Keep an eye on the latest College Football odds from the top online betting sites and monitor how the lines change throughout the week.

The Troy Trojans are the biggest favorites of the week with a -2400 moneyline and favored by 23 points. Texas Tech is the second largest favorite with a -13 spread and a -550 line against BYU. A handful of these Conference Championships are handicapped at small lines and tight outcomes. The Kennesaw State vs. Jacksonville State matchup for the Conference USA title has the largest Total of Week 15 at 60 points.

Make sure you check ScoresandStats top handicappers each week of the College Football season. They can help you understand how to approach some of these point spreads and game totals.

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College Football Week 15 Predictions

Let’s take a look at the featured College Football Week 15 games and make our NCAAF picks for each game.

Kennesaw State Owls @ Jacksonville State Gamecocks Odds

These are two of the younger football programs in the FBS. They have played a total of six times, with a handful of those games coming as members of the FCS. The two teams even met in an FCS playoff game back in 2017.

Jacksonville State has won three straight against the Owls, including a 35-26 win just a couple weeks ago in regular season play. Kennesaw State outgained Jacksonville but had four costly turnovers and lost. As a result, the Gamecocks get the advantage of playing at home for the Conference USA championship.

Kennesaw State Owls @ Jacksonville State Gamecocks Predictions

The Jacksonville State Gamecocks (8-4) and Kennesaw State Owls (9-3) will square off in an exciting rematch for the Conference USA Championship this Friday.

The storyline of this game is “revenge or repeat?” The Owls have won nine of their last 10 games. The only loss, of course, was to Jacksonville State. The books really like the Owls to get revenge.

The line opened with the Gamecocks as the home favorite, but early betting has seen the Owls get hammered. The result is a line flip that now has Kennesaw State as the 2.5-point favorite.

In that regular season game, Kennesaw State racked up 579 total yards on offense. Turnovers and a game-changing Hail Mary were the decisive factors. Both teams have potent attacks run led by first-year head coaches, so expect fireworks in this championship game.

The Owls defense ranks seventh in the conference against the run with an average of 172.6 yards per game. KSU faces a formidable battle against Jacksonville State’s rushing attack, which is ranked third nationally. The Gamecocks run for 262.5 yards per game.

Jacksonville State also has an 11-game home win streak and, don’t forget, the Gamecocks are the defending conference champs. QB Caden Creel has recorded 100+ passing and rushing yards in four straight games. He ran for 127 yards and two touchdowns and threw for 137 yards in the first match versus KSU.

JSU RB Cam Cook has tied a program record with seven straight 100-yard rushing games and leads the FBS in all-purpose yards (153.67 per game). He is the driving force behind the JSU attack with 1,581 running yards and 15 touchdowns.

With five one-possession victories this season, tied for the most in the FBS, Kennesaw State comes into the title game on a high note. They won last week by defeating Liberty in an exciting double-overtime match. That win earned the Owls a trip to the conference title game.

This season, QB Amari Odom had been outstanding (2,139 passing yards, 17 touchdowns), but in the defeat to JSU, he threw three of his six interceptions. KSU’s offense, which produced 579 yards in the opening game, can score points quickly.

KSU leads CUSA in team sacks (2.42/game) and ranks second in tackles for loss (6.6/game), demonstrating their potent defensive front as well. The Owls need to slow down JSU’s run game and force Creel to throw.

With the line flip, it seems now there is some value on the home underdog. Remember, JSU has 11 straight home wins. With a powerful run game and a slightly better defense, Gamecocks win another title.

Bet: JSU +114, JSU +2.5 (-110), Over 59.5 (-110)

Troy Trojans @ James Madison Dukes Odds

Troy and James Madison don’t have much history and the history they do have is from years ago when both were members of the FCS. You have to go back to the late 1990s to find two playoff games between these two opponents. They split those games.

The two met in 2023 in Troy. JMU won that game 16-14 and now the Sun Belt’s top two teams will play for the conference championship. Troy won the Sun Belt championship in 2022 and 2023. Marshall was last year’s champion.

Troy Trojans @ James Madison Dukes Predictions

The Sun Belt Championship kicks off conference championship action on Friday, December 5th, at 7:00 PM. James Madison is a huge favorite according to the early lines. The spread is now -23.5, and the total is sitting at 47.5 points. Troy is notorious for being a tough out in conference play, but the Dukes are riding a massive wave of momentum and are hoping to finish off a successful season.

It’s a huge game for the Dukes, who still have a shot at earning a College Football Playoff berth. A win, especially a big win, will only pad the Duke’s resume which currently shows an 11-1 record with the only loss to a pretty good Louisville team back in Week 2.

JMU is clearly better in almost every aspect of the game, according to the numbers. The Dukes are fifth in the country against the run and 10th in scoring defense. The offense is explosive. JMU has the ninth-best rushing offense in the country led by QB Alonza Barnett, a major dual threat. JMU averages 37.8 points per game, which is 10th in the nation.

Troy has had trouble scoring all season. The Trojans rank in the bottom 30 in rushing and average a very mediocre 25.2 points per game. Defense is what earned them this shot at the Sun Belt title. Troy held five of its last six opponents to 23 points or fewer. Holding JMU to 32 or less will be a chore. The Dukes scored 24 or more points in each of their last seven games.

JMU has won its last 12 games at home. With a chance to get into the CFP and with head coach Bob Chesney leaving to go to UCLA, the Dukes are going to play inspired.

Bet: ML pass, JMU -23.5 (-108), Over 47.5 (-105)

North Texas Mean Green @ Tulane Green Wave Odds

These two programs have met three times, two of which have come with both teams as members of the American Athletic Conference. Tulane has won all three games.

The Green Wave won last year in a shootout, 45-37. That game was played in Denton, Tex., home of the Mean Green. In 2023, Tulane won 35-28 at home.

Last year’s game total was 70.5 and the game did cash on the Over. This year, there hasn’t been much action on the total. It opened at 66 at most books and is up to 66.5.

North Texas Mean Green @ Tulane Green Wave Predictions

The Mean Green (11-1) will travel to play No. 24 Tulane (10-2) on Friday in the AAC Championship. This game is huge because the winner might potentially earn a spot in the College Football Playoffs.

The winner most likely gets a berth in the enlarged College Football Playoff, but it will depend upon how the rest of championship weekend shakes out. This game pits Tulane’s opportunistic, home-field-dominant defense against North Texas’s dynamic, high-octane offense.

It’s interesting that both head coaches in this game will be leaving for new schools. Jon Sumrall of Tulane is going to Florida, and Eric Morris of North Texas is leaving for Oklahoma State. The two coaches have committed to remaining through the title and any possible appearance in the CFP.

North Texas has the most prolific offense in the country. The Mean Green average 46.75 points per game. They lead the nation in total offense (511.8 ypg) and they are second in passing offense (325.7 ypg). QB Drew Mestemaker leads the FBS in passing with 3,836 yards. He also has 29 touchdown passes and just four interceptions. True freshman RB Caleb Hawkins leads the country with 26 total touchdowns.

Tulane is led by QB Jake Retzlaff who has 2,717 passing yards and 561 more on the ground. Tulane needs to attack the North Texas run defense. The Mean Green rank 129th in the nation, giving up 208 rushing yards per game.

The Over has cashed in 9 of North Texas’ 12 games. The Mean Green have scored 50 or more in five of their last six. Tulane ranks 121st in pass defense and 84th in the red zone. Those are going to be problems for the home team.

Bet: North Texas -130, North Texas -2.5 (-112), Over 66.5 (-110)

UNLV Rebels @ Boise State Broncos Odds

UNLV and Boise State have met 15 times throughout the history of college football. The Broncos have 12 wins. They have won the last 10 straight meetings. That dates back to 1977.

Included in there are two meetings in this game, the Mountain West Conference championship. The two teams met at the end of the 2024 season. Boise won 21-7 and they also picked up a 44-20 win in the 2023 MWC title game.

UNLV Rebels @ Boise State Broncos Predictions

It’s a high-stakes rematch for the Mountain West Championship. As mentioned, the two teams have played for the title twice before. The Broncos have won both games and are favored to win this one.

Boise State gets the luxury of playing this game at home on the blue turf. Since 2022, the Broncos are 22-4 at home. It will take a superhuman effort to beat the Broncos in Boise. The big news is that QB Maddux Madsen will return to play in this game.

Madsen has been out for about a month and the Broncos offense struggled in losses to Fresno State and San Diego State. Madsen was around when Boise played UNLV on Oct. 18. The Broncos won that game 56-31. Madsen threw for four touchdowns and RB Dylan Riley had 201 yards and a touchdown.

UNLV’s offense is explosive too. The Rebels are 12th in the nation in scoring, averaging 37.2 points per game. UNLV’s offense ranks in the top 35 in both passing and rushing. Boise’s run defense is weak as is the UNLV run defense. The bottom line is that both teams should have some offensive success.

The line for this game opened at Boise State -1.5. It’s already been bet up to 4.5. Boise State’s home dominance and the return of their starting quarterback will lead them to yet another Mountain West title.

Bet: Boise State -185, Boise State -4.5, (-108), Under 58.5 (-105)

BYU Cougars @ Texas Tech Red Raiders Odds

Most will be focused on the recent meeting between these two schools. Texas Tech, of course, was a 29-7 winner over BYU back on Nov. 8. Now, we get the rematch.

These two programs have only played three times in college football history. One was last month, a second in 2023 and the third time was back before the U.S. entered World War II (1940). The Red Raiders hold a 2-1 advantage in the series.

BYU Cougars @ Texas Tech Red Raiders Predictions

This is for the Big 12 Championship and will be played Saturday at AT&T Stadium in Arlington, Texas. That gives the Red Raiders somewhat of an advantage as Texas Tech is located in Lubbock.

It’s very difficult to beat a team twice in one season, especially by margin. The Red Raiders are outstanding. There’s no question about that. Both these teams want this win because it means an automatic berth into the College Football Playoff.

The game will likely come down to defense. Which defense can stop the opponent? Texas Tech held BYU to just seven points in the first meeting. BYU actually held Texas Tech below its season average and, if not for a few costly turnovers, may have held the Red Raiders to even less.

The Red Raiders run defense is elite – first in the nation allowing 71.2 yards per game. BYU has one of the better ground games in the FBS. Can they run the football on the Red Raiders? In that game in November, they could not, managing just 67 yards.

The Red Raiders offense is equally impressive. They are third in the country in points per game with 43.2 per game. The run game is outstanding and the passing game, led by QB Behren Morton, is one of the nation’s best.

Don’t count out the Cougars defense though. They rank 14th in the nation in scoring defense, allowing just 17.7 points per game. The Cougars did hold Texas Tech below their season averages in that regular season game. BYU had three turnovers which was the difference.

With Kilani Sitake turning down Penn State and signing a huge contract extension, his team will be dialed in and play with nothing to lose. The Cougars should still receive a bid to the CFP even with a loss. They’ll let it all hang out on Saturday.

Bet: ML pass, BYU +12.5 (-105), Under 49.5 (-112)

Miami (OH) RedHawks @ Western Michigan Broncos Odds

These two have played each other quite a bit as members of the MAC. They’ve played 64 times in total. If you go back to the days of divisions in the MAC, remember that these two teams were in different divisions and, as a result, didn’t play each other every year.

They did meet in the regular season this year. Miami won at home on Oct. 25, 26-17. The RedHawks also won in 2023, beating the Broncos 34-21 in Kalamazoo, the site of this MAC championship game.

Prior to those two meetings, Western Michigan had won eight straight against the RedHawks. That dated back to 2006.

Miami (OH) RedHawks @ Western Michigan Broncos Predictions

This game will be played at Ford Field in Detroit, Mich., and will kick off at 12:00 p.m. ET. The RedHawks got into this game by virtue of a tiebreaker. It’s the third straight trip for Miami to the MAC title game. Western Michigan is making its first trip to the title game since 2016 when the Broncos beat Ohio 29-23 for the championship.

It should be a low-scoring game featuring a very strong WMU defense and a Miami team that likes to run the football. The RedHawks also had some issues at quarterback. Starter Dequan Finn left the program late in the season and Thomas Gostkowski stepped in to take over.

The Broncos allowed just 14.5 points per game in MAC games this season. Miami’s offense is mediocre at best, averaging 26.1 points per game. The RedHawks are also down to their fourth and fifth running backs.

Miami won that first game 26-17. They were a 2.5-point favorite. Now, they are a 2.5-point underdog on the road against the best defense in the MAC. The numbers don’t lie. This is a Western Michigan spot.

Bet: WMU -130, WMU -2.5 (-108), Under 43.5 (-112)

Georgia Bulldogs @ Alabama Crimson Tide Odds

Georgia and Alabama have been long-time SEC rivals. The two powers have played 75 times and the Crimson Tide own the series advantage 45-26-4. Alabama has won the last three meetings, including this season’s regular season game. The Tide won 24-21.

Georgia has just one win in the series since 2008. That win was a big one. The Bulldogs won the national championship at the end of the 2021 season.

Georgia Bulldogs @ Alabama Crimson Tide Predictions

This could very well be the most important game of the college football season. No. 3 Georgia takes on No. 9 Alabama at Mercedes-Benz Stadium in Atlanta. The Bulldogs get a little bit of an edge with the game close to their home in Athens.

Georgia is a 2.5-point favorite just like they were when the teams met in September. The game total in that one was set at 54. Now, we’re seeing 47.5. This should also be a close game just like the regular season matchup.

There is the revenge factor, but that’s been the case in many of these Georgia-Alabama games over the past decade. The Tide keep winning, but Alabama did end Georgia’s 33-game home winning streak in September.

Both these teams are outstanding. The defenses are both elite, which is reflected in the total. The big thing going for Georgia … head coach Kirby Smart. In rematches in the same season, Smart and Georgia are 3-0 SU. It’s hard to beat a team twice in one season, especially when that team is the Bulldogs. Over their last three games, the Georgia defense has allowed just 7.3 points per game

Alabama has a top-10 passing game and Ty Simpson is one of the best quarterbacks in the nation. The Bulldogs pass defense is very good, but has been susceptible to elite offenses. This should be a battle, but there’s a reason Georgia is favored again.

Bet: Georgia -135, Georgia -2.5 (-105), Under 47.5 (-105)

Indiana Hoosiers @ Ohio State Buckeyes Odds

Indiana used to be a joke in the Big Ten. They were the team you scheduled for homecoming. Not anymore.

The Hoosiers are ranked No. 2 in the nation and head coach Curt Cignetti has his team at 12-0, just like Ohio State. The Buckeyes, of course, rule this series. These two Big Ten schools have played 97 times.

Ohio State is 80-12-5 all-time. The Buckeyes have actually won 30 straight in the series. That includes last year’s 38-15 win against the Hoosiers in the regular season. The win in 2010 was vacated, but the Buckeyes did win that game on the field. The last time the Hoosiers didn’t lose to Ohio State was in 1990. The two teams played to a 27-27 tie. The Hoosiers last win came in 1988.

Indiana Hoosiers @ Ohio State Buckeyes Predictions

These are the two best teams in the country. They are both elite on offense and elite on defense. Indiana is second in the nation in scoring offense – 44.3 points per game. Ohio State is 13th (37.3).

The defenses rank No. 1 and 2 in scoring. Ohio State allows 7.8 points per game while the Hoosiers give up 10.9. Ohio State QB Julian Sayin is young, but he has matured through the season and he has a bevy of NFL-ready receivers like Jeremiah Smith to throw to.

Fernando Mendoza is the Heisman Trophy favorite and is a dual threat quarterback that can give even the best defenses fits. Elijah Sarratt is another NFL caliber receiver for the Hoosiers and the run game is ninth in the nation, averaging 229.8 yards per game.

It’s hard to bet against either team or head coach. So, we’ll follow the line movement. This line opened at Ohio State -6.5. It’s down to 4.5 and even as of this writing there are some 3.5s out there. We’ll back Cignetti and the Hoosiers. He wins. Google him.

Bet: Ohio State -194, Indiana +4.5 (-115), Over 47.5 (-115)

Duke Blue Devils @ Virginia Cavaliers Odds

These two ACC rivals have met 76 times. Virginia holds a 42-34 advantage in the series. That includes a 34-17 win over the Blue Devils in Durham back in November of this year. Virginia has won eight of the last nine meetings.

Duke’s only win over those last nine games came in 2022. The Blue Devils won at home 38-17.

Duke Blue Devils @ Virginia Cavaliers Predictions

For the first time in school history, Virginia ended alone at the top of the ACC standings. A win over Duke would mark their first ACC Championship. Duke, on the other hand, would like to cap off an historic run to the title game.

Interestingly, since 1906, Virginia has not faced the same opponent twice in a single season. That makes this title game an unprecedented rematch. The Cavaliers are on a high after defeating Duke in the regular season and winning four in a row on the road..

In that regular season meeting, Virginia outgained Duke 540 to 255. The Blue Devils were held to season lows in rushing and passing yards and were held well below their 34.6 points per game average.

Virginia also has an elite offense, scoring over 33 points per game, but it’s the defense that gets it done for the Cavaliers. They have kind of flown under the radar this season, but the Cavs are No. 24 in the nation in scoring defense allowing just 20 points per game.

That defense is the difference in this game on Saturday night. Duke was favored in that regular season game and now the team is playing in North Carolina and Virginia is still favored by 2.5.

Bet: Virginia -166, Virginia -3.5 (-110), Over 57.5 (-110)

College Football Week 15 Best Bets

Here are our favorite bets for Week 15 of the College Football season:

• Indiana Hoosiers +4.5 (-115) @ Ohio State Buckeyes
• North Texas Mean Green -2.5 (-112) @ Tulane Green Wave
• Troy Trojans @ James Madison Dukes-23.5 (-108)

This is it. These Conference Championship games are huge for many reasons. The biggest reason for most teams that will play this weekend is the College Football Playoff. Wins by North Texas and James Madison, for instance, could lead to a playoff berth.

Our experts love the North Texas offense. In a shootout, the Tulane offense just doesn’t have the same firepower of the Mean Green. North Texas leads the nation in scoring and they’ve hit 50-plus in five of their last six games.

James Madison is such a huge favorite for a reason. The line opened around -21 and don’t be surprised if it closes over -24. The Dukes are an offensive machine and the defense can stifle an underachieving Troy offense.

The Big Ten title game features the two best teams in the country. It should be a good one. After losing big to Ohio State last year, many thought the Hoosiers would come back in 2025 and not be as good as last year’s team. They were right. This year’s team is better. The line has moved in Indiana’s favor and we’ll back the Hoosiers plus the 4.5.

If you want to add all three of our NCAAF Week 15 best bets to a parlay card, then you could earn $579 on a $100 wager. That’s nearly a 6x ROI on your investment. If you love compiling parlay cards, then check out our best College Football parlays of the week. We also have our best NFL parlay picks, as well.